Nanostructured Copper Surface Kills ESKAPE Pathogens and Viruses in Minutes

In the search for a fast contact-killing antimicrobial surface to break the transmission pathway of lethal pathogens, nanostructured copper surfaces were found to exhibit the desired antimicrobial properties. Compared with plain copper, these nanostructured copper surfaces with Cu(OH)(2) nano-sword or CuO nano-foam were found to completely eliminate pathogens at a fast rate, including clinically isolated drug resistant species. Additionally these nanostructured copper surfaces demonstrated potential antiviral properties when assessed against bacteriophages, as a viral surrogate, and murine hepatitis virus, a surrogate for SARS-CoV-2. The multiple modes of killing, physical killing and copper ion mediated killing contribute to the superior and fast kinetics of antimicrobial action against common microbes, and ESKAPE pathogens. Prototypes for air and water cleaning with current nanostructured copper surface have also been demonstrated.

Automated summary

Nanostructured copper surfaces show superior antimicrobial properties, rapidly eliminating pathogens including drug-resistant strains, and demonstrating potential antiviral effects. These surfaces employ multiple modes of killing, such as physical and copper ion mediated mechanisms, providing significant efficacy against a range of microbes and deadly pathogens.