4.5 Article

Hydrogean Peroxide Inducible Acid-Activatable Prodrug for Targeted Cancer Treatment

Related references

Note: Only part of the references are listed.
Review Chemistry, Multidisciplinary

The Use of Alternative Strategies for Enhanced Nanoparticle Delivery to Solid Tumors

Mukaddes Izci et al.

Summary: Research has shown that despite efforts to utilize the EPR effect for enhanced delivery of nanomaterials to solid tumors, the results are still poor. Furthermore, some studies question the role of the EPR effect, suggesting that nanomaterials may enter tumors through active mechanisms rather than through endothelial gaps.

CHEMICAL REVIEWS (2021)

Review Cell Biology

The redox language in neurodegenerative diseases: oxidative post-translational modifications by hydrogen peroxide

Yew Mun Lee et al.

Summary: Cellular ROS can drive important biological signaling pathways through redox signaling, with mitochondria and mitochondrial H2O2 potentially implicated in the pathogenesis of neurodegenerative diseases.

CELL DEATH & DISEASE (2021)

Article Chemistry, Multidisciplinary

Real-Time Evaluation of Hydrogen Peroxide Injuries in Pulmonary Fibrosis Mice Models with a Mitochondria-Targeted Near-Infrared Fluorescent Probe

Xinyu Song et al.

Summary: The study focused on the molecular mechanism of oxidative stress in pulmonary fibrosis, and designed a mitochondria-targeted fluorescent probe for detecting H2O2 levels. The probe showed excellent fluorescence performance and biocompatibility in living cells and mouse models. It can be utilized for studying pulmonary fibrosis and modulating H2O2 levels to slow down disease progression.

ACS SENSORS (2021)

Review Nanoscience & Nanotechnology

Targeted drug delivery strategies for precision medicines

Mandana T. Manzari et al.

Summary: Precision medicine offers personalized treatment strategies for individual patients, especially in the field of cancer therapy. While there have been some clinical successes, challenges such as drug toxicities and resistance still hinder the full potential of precision medicine. Advanced drug delivery materials and approaches provide opportunities to improve therapeutic outcomes and overcome pharmacological issues in cancer treatment.

NATURE REVIEWS MATERIALS (2021)

Article Chemistry, Organic

A Mild Method for Making MIDA Boronates

Aidan M. Kelly et al.

ORGANIC LETTERS (2020)

Review Gastroenterology & Hepatology

Evaluation of liver tumour response by imaging

Jules Gregory et al.

JHEP REPORTS (2020)

Article Chemistry, Multidisciplinary

Halohydroxylation of alkenyl MIDA boronates: switchable stereoselectivity induced by B(MIDA) substituent

Yao-Fu Zeng et al.

CHEMICAL COMMUNICATIONS (2020)

Article Nanoscience & Nanotechnology

Light-Activatable Prodrug and AIEgen Copolymer Nanoparticle for Dual-Drug Monitoring and Combination Therapy

Peng Wu et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

Review Chemistry, Multidisciplinary

Fluorescent probes for the simultaneous detection of multiple analytes in biology

Jacek L. Kolanowski et al.

CHEMICAL SOCIETY REVIEWS (2018)

Review Materials Science, Biomaterials

Leveraging H2O2 Levels for Biomedical Applications

Jinqiang Wang et al.

ADVANCED BIOSYSTEMS (2017)

Review Biochemistry & Molecular Biology

Next generation NIR fluorophores for tumor imaging and fluorescence-guided surgery: A review

Ashanul Hague et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2017)

Article Chemistry, Organic

Building Block Approach for the Synthesis of Sulfoximines

Anne-Dorothee Steinkamp et al.

ORGANIC LETTERS (2016)

Article Biochemistry & Molecular Biology

Reversible Cysteine Oxidation in Hydrogen Peroxide Sensing and Signal Transduction

Sarela Garcia-Santamarina et al.

BIOCHEMISTRY (2014)

Review Chemistry, Multidisciplinary

Selection of boron reagents for Suzuki-Miyaura coupling

Alastair J. J. Lennox et al.

CHEMICAL SOCIETY REVIEWS (2014)

Article Chemistry, Multidisciplinary

A Palette of Fluorescent Probes with Varying Emission Colors for Imaging Hydrogen Peroxide Signaling in Living Cells

Bryan C. Dickinson et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

Article Biochemistry & Molecular Biology

Molecular imaging of hydrogen peroxide produced for cell signaling

Evan W. Miller et al.

NATURE CHEMICAL BIOLOGY (2007)