Related references
Note: Only part of the references are listed.UCSF ChimeraX: Structure visualization for researchers, educators, and developers
Eric F. Pettersen et al.
PROTEIN SCIENCE (2021)
International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function
Nicholas M. Barnes et al.
PHARMACOLOGICAL REVIEWS (2021)
Structural insights into the lipid and ligand regulation of serotonin receptors
Peiyu Xu et al.
NATURE (2021)
Conformational plasticity and dynamic interactions of the N-terminal domain of the chemokine receptor CXCR1
Shalmali Kharche et al.
PLOS COMPUTATIONAL BIOLOGY (2021)
A molecular sensor for cholesterol in the human serotonin1A receptor
G. Aditya Kumar et al.
SCIENCE ADVANCES (2021)
Statin-Induced Chronic Cholesterol Depletion Switches GPCR Endocytosis and Trafficking: Insights from the Serotonin1A Receptor
G. Aditya Kumar et al.
ACS CHEMICAL NEUROSCIENCE (2020)
Cholesterol interaction motifs in G protein-coupled receptors: Slippery hot spots?
Parijat Sarkar et al.
WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE (2020)
Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor
Kuglae Kim et al.
CELL (2020)
The discovery of a new antibody for BRIL-fused GPCR structure determination
Hikaru Miyagi et al.
SCIENTIFIC REPORTS (2020)
Structural Stringency and Optimal Nature of Cholesterol Requirement in the Function of the Serotonin1A Receptor
Parijat Sarkar et al.
JOURNAL OF MEMBRANE BIOLOGY (2020)
Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine
Kanako Terakado Kimura et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2019)
Extramembranous Regions in G Protein-Coupled Receptors: Cinderella in Receptor Biology?
Sreetama Pal et al.
JOURNAL OF MEMBRANE BIOLOGY (2019)
Cholesteryl Hemisuccinate Is Not a Good Replacement for Cholesterol in Lipid Nanodiscs
Bozena Augustyn et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2019)
New Binding Sites, New Opportunities for GPCR Drug Discovery
H. C. Stephen Chan et al.
TRENDS IN BIOCHEMICAL SCIENCES (2019)
5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology
Yao Peng et al.
CELL (2018)
G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?
Krishna Sriram et al.
MOLECULAR PHARMACOLOGY (2018)
Crystal structure of the human 5-HT1B serotonin receptor bound to an inverse agonist
Wanchao Yin et al.
CELL DISCOVERY (2018)
Cryo-EM structure of the serotonin 5-HT1B receptor coupled to heterotrimeric Go
Javier Garcia-Nafria et al.
NATURE (2018)
Structural determinants of 5-HT2B receptor activation and biased agonism
John D. McCorvy et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody
Andrii Ishchenko et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Membrane cholesterol oxidation in live cells enhances the function of serotonin1A receptors
Md. Jafurulla et al.
CHEMISTRY AND PHYSICS OF LIPIDS (2017)
G protein coupled receptor interactions with cholesterol deep in the membrane
Samuel Genheden et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2017)
Crystal Structure of an LSD-Bound Human Serotonin Receptor
Daniel Wacker et al.
CELL (2017)
The Functional Activity of the Human Serotonin 5-HT1A Receptor Is Controlled by Lipid Bilayer Composition
M. Gertrude Gutierrez et al.
BIOPHYSICAL JOURNAL (2016)
Molecular mechanisms of protein-cholesterol interactions in plasma membranes: Functional distinction between topological (tilted) and consensus (CARC/CRAC) domains
Jacques Fantini et al.
CHEMISTRY AND PHYSICS OF LIPIDS (2016)
Experimental determination and computational interpretation of biophysical properties of lipid bilayers enriched by cholesteryl hemisuccinate
Waldemar Kulig et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2015)
Methodological advances: the unsung heroes of the GPCR structural revolution
Eshan Ghosh et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)
A comprehensive review of the lipid cubic phase or in meso method for crystallizing membrane and soluble proteins and complexes
Martin Caffrey
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS (2015)
5-HT1A Receptor: An Old Target as a New Attractive Tool in Drug Discovery from Central Nervous System to Cancer
Ferdinando Fiorino et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
How well does cholesteryl hemisuccinate mimic cholesterol in saturated phospholipid bilayers?
Waldemar Kulig et al.
JOURNAL OF MOLECULAR MODELING (2014)
Atorvastatin evokes a serotonergic system-dependent antidepressant-like effect in mice
Fabiana K. Ludka et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2014)
Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator
Huixian Wu et al.
SCIENCE (2014)
Membrane Lipids in the Function of Serotonin and Adrenergic Receptors
Md. Jafurulla et al.
CURRENT MEDICINAL CHEMISTRY (2013)
Structural Basis for Molecular Recognition at Serotonin Receptors
Chong Wang et al.
SCIENCE (2013)
Structural Features for Functional Selectivity at Serotonin Receptors
Daniel Wacker et al.
SCIENCE (2013)
Serial Femtosecond Crystallography of G Protein-Coupled Receptors
Wei Liu et al.
SCIENCE (2013)
How cholesterol interacts with membrane proteins: an exploration of cholesterol-binding sites including CRAC, CARC, and tilted domains
Jacques Fantini et al.
FRONTIERS IN PHYSIOLOGY (2013)
Identification of Cholesterol Binding Sites in the Serotonin1A Receptor
Durba Sengupta et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2012)
Why GPCRs behave differently in cubic and lamellar lipidic mesophases
George Khelashvili et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions
Wei Liu et al.
SCIENCE (2012)
Identification of cholesterol recognition amino acid consensus (CRAC) motif in G-protein coupled receptors
Md. Jafurulla et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Functional characterization of putative cholesterol binding sequence (CRAC) in human type-1 cannabinoid receptor
Sergio Oddi et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Organization and Dynamics of Membrane Probes and Proteins Utilizing the Red Edge Excitation Shift
Sourav Haldar et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2011)
Disclosure of cholesterol recognition motifs in transmembrane domains of the human nicotinic acetylcholine receptor
Carlos J. Baier et al.
SCIENTIFIC REPORTS (2011)
Chronic Cholesterol Depletion Using Statin Impairs the Function and Dynamics of Human Serotonin1A Receptors
Sandeep Shrivastava et al.
BIOCHEMISTRY (2010)
Are specific nonannular cholesterol binding sites present in G-protein coupled receptors?
Yamuna Devi Paila et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)
The function of G-protein coupled receptors and membrane cholesterol: specific or general interaction?
Yamuna Devi Paila et al.
GLYCOCONJUGATE JOURNAL (2009)
Signaling by the human serotonin1A receptor is impaired in cellular model of Smith-Lemli-Opitz Syndrome
Yamuna Devi Paila et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2008)
Serotonin receptors
David E. Nichols et al.
CHEMICAL REVIEWS (2008)
5-HT1A receptor, an old target for new therapeutic agents
Enza Lacivita et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2008)
Cholesterol reduction attenuates 5-HT1A receptor-mediated signaling in human primary neuronal cultures
Benita Sjogren et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2008)
A specific cholesterol binding site is established by the 2.8 Å structure of the human β2-adrenergic receptor
Michael A. Hanson et al.
STRUCTURE (2008)
High-resolution crystal structure of an engineered human β2-adrenergic G protein-coupled receptor
Vadim Cherezov et al.
SCIENCE (2007)
GPCR engineering yields high-resolution structural insights into β2-adrenergic receptor function
Daniel M. Rosenbaum et al.
SCIENCE (2007)
A monoclonal antibody for G protein-coupled receptor crystallography
Peter W. Day et al.
NATURE METHODS (2007)
Lipid-protein interactions, regulation and dysfunction of brain cholesterol
Amitabha Chattopadhyay et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Cholesterol depletion induces dynamic confinement of the G-protein coupled serotonin1A receptor in the plasma membrane of living cells
Thomas J. Pucadyil et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2007)
Serotonin and psychostimulant addiction:: Focus on 5-HT1A-receptors
Christian P. Mueller et al.
PROGRESS IN NEUROBIOLOGY (2007)
Use of cyclodextrins to manipulate plasma membrane cholesterol content: Evidence, misconceptions and control strategies
Raphael Zidovetzki et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2007)
Role of cholesterol in the function and organization of G-protein coupled receptors
Thomas J. Pucadyil et al.
PROGRESS IN LIPID RESEARCH (2006)
Cholesterol and the interaction of proteins with membrane domains
Richard M. Epand
PROGRESS IN LIPID RESEARCH (2006)
Lipid-protein interactions in double-layered two-dimensional AQPO crystals
T Gonen et al.
NATURE (2005)
Cholesterol modulates the antagonist-binding function of hippocampal serotonin1A receptors
TJ Pucadyil et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2005)
Membrane cholesterol oxidation inhibits ligand binding function of hippocampal serotonin1A receptors
TJ Pucadyil et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
The serotonin1A receptor:: A representative member of the serotonin receptor family
TJ Pucadyil et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2005)
The cholesterol-complexing agent digitonin modulates ligand binding of the bovine hippocampal serotonin1A receptor
YD Paila et al.
MOLECULAR MEMBRANE BIOLOGY (2005)
Caveolin scaffolding region and cholesterol-rich domains in membranes
RM Epand et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Calmodulin interacts with the third intracellular loop of the serotonin 5-hydroxytryptamine1A receptor at two distinct sites -: Putative role in receptor phosphorylation by protein kinase C
JH Turner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The sterol-binding antibiotic nystatin differentially modulates ligand binding of the bovine hippocampal serotonin1A receptor
TJ Pucadyil et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
How lipids affect the activities of integral membrane proteins
AG Lee
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2004)
Cholesterol modulates ligand binding and G-protein coupling to serotonin 1A receptors from bovine hippocampus
TJ Pucadyil et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2004)
Lipid-protein interactions in biological membranes: a structural perspective
AG Lee
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2003)
Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice
JA Gingrich et al.
PSYCHOPHARMACOLOGY (2001)
Cholesterol metabolism in the brain
JM Dietschy et al.
CURRENT OPINION IN LIPIDOLOGY (2001)
Crystal structure of rhodopsin: A G protein-coupled receptor
K Palczewski et al.
SCIENCE (2000)