Journal
CHEMICAL REVIEWS
Volume 122, Issue 2, Pages 2752-2906Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.chemrev.1c00332
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Funding
- European Union [840724]
- FETopen (FLIX) [862179]
- RIA-NMBP (FlowPhotoChem) [862453]
- Dutch Research Council (NWO) [18433]
- Marie Curie Actions (MSCA) [840724] Funding Source: Marie Curie Actions (MSCA)
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This paper provides a comprehensive overview of the exciting technological advances in the field of photoinduced chemical transformations, including flow chemistry, high-throughput experimentation, reactor design and scale-up, and the combination of photo- and electro-chemistry.
Photoinduced chemical transformations have received in recent years a tremendous amount of attention, providing a plethora of opportunities to synthetic organic chemists. However, performing a photochemical transformation can be quite a challenge because of various issues related to the delivery of photons. These challenges have barred the widespread adoption of photochemical steps in the chemical industry. However, in the past decade, several technological innovations have led to more reproducible, selective, and scalable photoinduced reactions. Herein, we provide a comprehensive overview of these exciting technological advances, including flow chemistry, high-throughput experimentation, reactor design and scale-up, and the combination of photo- and electro-chemistry.
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