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ACCOUNTS OF CHEMICAL RESEARCH (2014)
Native Top-Down Electrospray Ionization-Mass Spectrometry of 158 kDa Protein Complex by High-Resolution Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
Huilin Li et al.
ANALYTICAL CHEMISTRY (2014)
Affecting Protein Charge State Distributions in Nano-Electrospray Ionization via In-Spray Solution Mixing Using Theta Capillaries
Christine M. Fisher et al.
ANALYTICAL CHEMISTRY (2014)
Anions in Electrothermal Supercharging of Proteins with Electrospray Ionization Follow a Reverse Hofmeister Series
Catherine A. Cassou et al.
ANALYTICAL CHEMISTRY (2014)
Photodissociation mass spectrometry: new tools for characterization of biological molecules
Jennifer S. Brodbelt
CHEMICAL SOCIETY REVIEWS (2014)
Dynamic protein ligand interactions - insights from MS
Carla Schmidt et al.
FEBS JOURNAL (2014)
Characterization of Native Protein Complexes Using Ultraviolet Photodissociation Mass Spectrometry
John P. O'Brien et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Charge Reduction Stabilizes Intact Membrane Protein Complexes for Mass Spectrometry
Shahid Mehmood et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Measuring Positive Cooperativity Using the Direct ESI-MS Assay. Cholera Toxin B Subunit Homopentamer Binding to GM1 Pentasaccharide
Hong Lin et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2014)
Identifying Carbohydrate Ligands of a Norovirus P Particle using a Catch and Release Electrospray Ionization Mass Spectrometry Assay
Ling Han et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2014)
Effects of Cations on Protein and Peptide Charging in Electrospray Ionization from Aqueous Solutions
Anna C. Susa et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2014)
Screening Carbohydrate Libraries for Protein Interactions Using the Direct ESI-MS Assay. Applications to Libraries of Unknown Concentration
Elena N. Kitova et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2014)
Boundaries of Mass Resolution in Native Mass Spectrometry
Philip Lossl et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2014)
Membrane proteins bind lipids selectively to modulate their structure and function
Arthur Laganowsky et al.
NATURE (2014)
Structural basis for hijacking siderophore receptors by antimicrobial lasso peptides
Indran Mathavan et al.
NATURE CHEMICAL BIOLOGY (2014)
The power of ion mobility-mass spectrometry for structural characterization and the study of conformational dynamics
Francesco Lanucara et al.
NATURE CHEMISTRY (2014)
Application of the Exactive Plus EMR for automated protein-ligand screening by non-covalent mass spectrometry
Hannah J. Maple et al.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2014)
Allosteric modulation of protein oligomerization: an emerging approach to drug design
Ronen Gabizon et al.
FRONTIERS IN CHEMISTRY (2014)
Applications of Biophysics in High-Throughput Screening Hit Validation
Christine Clougherty Genick et al.
JOURNAL OF BIOMOLECULAR SCREENING (2014)
Plasmodium Gametocyte Inhibition Identified from a Natural-Product-Based Fragment Library
Hoan Vu et al.
ACS CHEMICAL BIOLOGY (2013)
Electrothermal Supercharging in Mass Spectrometry and Tandem Mass Spectrometry of Native Proteins
Catherine A. Cassou et al.
ANALYTICAL CHEMISTRY (2013)
Unraveling the Mechanism of Electrospray Ionization
Lars Konermann et al.
ANALYTICAL CHEMISTRY (2013)
Effects of Polarity on the Structures and Charge States of Native-Like Proteins and Protein Complexes in the Gas Phase
Samuel J. Allen et al.
ANALYTICAL CHEMISTRY (2013)
Measuring Protein-Ligand Interactions Using Liquid Sample Desorption Electrospray Ionization Mass Spectrometry
Pengyuan Liu et al.
ANALYTICAL CHEMISTRY (2013)
Effects of Ammonium Bicarbonate on the Electrospray Mass Spectra of Proteins: Evidence for Bubble-Induced Unfolding
Jason B. Hedges et al.
ANALYTICAL CHEMISTRY (2013)
Quantifying Protein Interactions with Isomeric Carbohydrate Ligands Using a Catch and Release Electrospray Ionization-Mass Spectrometry Assay
Amr El-Hawiet et al.
ANALYTICAL CHEMISTRY (2013)
Quantifying Protein-Ligand Interactions by Direct Electrospray Ionization-MS Analysis: Evidence of Nonuniform Response Factors Induced by High Molecular Weight Molecules and Complexes
Hong Lin et al.
ANALYTICAL CHEMISTRY (2013)
Influence of Dimehylsulfoxide on Protein-Ligand Binding Affinities
Dragana Cubrilovic et al.
ANALYTICAL CHEMISTRY (2013)
From Protein Complexes to Subunit Backbone Fragments: A Multi-stage Approach to Native Mass Spectrometry
Mikhail E. Belov et al.
ANALYTICAL CHEMISTRY (2013)
Extending the Isotopically Resolved Mass Range of Orbitrap Mass Spectrometers
Jared B. Shaw et al.
ANALYTICAL CHEMISTRY (2013)
Activation State-Selective Kinase Inhibitor Assay Based on Ion Mobility-Mass Spectrometry
Jessica N. Rabuck et al.
ANALYTICAL CHEMISTRY (2013)
Orbitrap Mass Spectrometry
Roman A. Zubarev et al.
ANALYTICAL CHEMISTRY (2013)
Photodissociation and Dissociative Photoionization Mass Spectrometry of Proteins and Noncovalent Protein-Ligand Complexes
Francis Canon et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)
Fragment Screening by Native State Mass Spectrometry
Sally-Ann Poulsen
AUSTRALIAN JOURNAL OF CHEMISTRY (2013)
Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism
Douglas Marcotte et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
Evolving pharmacology of orphan GPCRs: IUPHAR Commentary
Anthony P. Davenport et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
Ion mobility-mass spectrometry of intact protein-ligand complexes for pharmaceutical drug discovery and development
Shuai Niu et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2013)
Molecular determinants of drug-receptor binding kinetics
Albert C. Pan et al.
DRUG DISCOVERY TODAY (2013)
Dramatically stabilizing multiprotein complex structure in the absence of bulk water using tuned Hofmeister salts
Linjie Han et al.
FARADAY DISCUSSIONS (2013)
Protein Structure in the Gas Phase: The Influence of Side-Chain Microsolvation
Stephan Warnke et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
From Solution to the Gas Phase: Stepwise Dehydration and Kinetic Trapping of Substance P Reveals the Origin of Peptide Conformations
Joshua A. Silveira et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Detergent Release Prolongs the Lifetime of Native-like Membrane Protein Conformations in the Gas-Phase
Antoni J. Borysik et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Dissociation Kinetics of the Streptavidin-Biotin Interaction Measured Using Direct Electrospray Ionization Mass Spectrometry Analysis
Lu Deng et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2013)
Mapping Protein-Ligand Interactions in the Gas Phase Using a Functional Group Replacement Strategy. Comparison of CID and BIRD Activation Methods
Lu Deng et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2013)
Dissociation of Multisubunit Protein-Ligand Complexes in the Gas Phase. Evidence for Ligand Migration
Yixuan Zhang et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2013)
Detergent-free mass spectrometry of membrane protein complexes
Jonathan T. S. Hopper et al.
NATURE METHODS (2013)
Mass spectrometry of intact membrane protein complexes
Arthur Laganowsky et al.
NATURE PROTOCOLS (2013)
Changing the shape of molecular ions: photoisomerization action spectroscopy in the gas phase
B. D. Adamson et al.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2013)
Mass spectrometry reveals synergistic effects of nucleotides, lipids, and drugs binding to a multidrug resistance efflux pump
Julien Marcoux et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Allosteric mechanisms can be distinguished using structural mass spectrometry
Andrey Dyachenko et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Intrinsically Disordered Protein Threads Through the Bacterial Outer-Membrane Porin OmpF
Nicholas G. Housden et al.
SCIENCE (2013)
Applications of a Catch and Release Electrospray Ionization Mass Spectrometry Assay for Carbohydrate Library Screening
Amr El-Hawiet et al.
ANALYTICAL CHEMISTRY (2012)
Quantifying Ligand Binding to Large Protein Complexes Using Electrospray Ionization Mass Spectrometry
Amr El-Hawiet et al.
ANALYTICAL CHEMISTRY (2012)
Exploring Key Parameters to Detect Subtle Ligand-Induced Protein Conformational Changes Using Traveling Wave Ion Mobility Mass Spectrometry
Cedric Atmanene et al.
ANALYTICAL CHEMISTRY (2012)
Electrothermal Supercharging of Proteins in Native Electrospray Ionization
Harry J. Sterling et al.
ANALYTICAL CHEMISTRY (2012)
Solution Additives that Desalt Protein Ions in Native Mass Spectrometry
Tawnya G. Flick et al.
ANALYTICAL CHEMISTRY (2012)
Protein Subunits Released by Surface Collisions of Noncovalent Complexes: Nativelike Compact Structures Revealed by Ion Mobility Mass Spectrometry
Mowei Zhou et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
Gas-phase protein assemblies: Unfolding landscapes and preserving native-like structures using noncovalent adducts
Joanna Freeke et al.
CHEMICAL PHYSICS LETTERS (2012)
Automated Protein-Ligand Interaction Screening by Mass Spectrometry
Hannah J. Maple et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Quantifying Protein-Ligand Binding Constants using Electrospray Ionization Mass Spectrometry: A Systematic Binding Affinity Study of a Series of Hydrophobically Modified Trypsin Inhibitors
Dragana Cubrilovic et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2012)
Ligand Migration in the Gaseous Insulin-CB7 Complex-A Cautionary Tale About the Use of ECD-MS for Ligand Binding Site Determination
Brittany L. Heath et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2012)
Do Charge State Signatures Guarantee Protein Conformations?
Zoe Hall et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2012)
Reliable Determinations of Protein-Ligand Interactions by Direct ESI-MS Measurements. Are We There Yet?
Elena N. Kitova et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2012)
High-sensitivity Orbitrap mass analysis of intact macromolecular assemblies
Rebecca J. Rose et al.
NATURE METHODS (2012)
Enabling Lead Discovery for Histone Lysine Demethylases by High-Throughput RapidFire Mass Spectrometry
Sue E. Hutchinson et al.
JOURNAL OF BIOMOLECULAR SCREENING (2012)
Quantifying Protein-Protein Interactions Within Noncovalent Complexes Using Electrospray Ionization Mass Spectrometry
Elisabetta Boeri Erba et al.
ANALYTICAL CHEMISTRY (2011)
Native Electrospray and Electron-Capture Dissociation FTICR Mass Spectrometry for Top-Down Studies of Protein Assemblies
Hao Zhang et al.
ANALYTICAL CHEMISTRY (2011)
Direct Ionization of Large Proteins and Protein Complexes by Desorption Electrospray Ionization-Mass Spectrometry
Carly N. Ferguson et al.
ANALYTICAL CHEMISTRY (2011)
Electrostatic Stabilization of a Native Protein Structure in the Gas Phase
Kathrin Breuker et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)
Ion Mobility Mass Spectrometry Studies of the Inhibition of Alpha Synuclein Amyloid Fibril Formation by (-)-Epigallocatechin-3-Gallate
Yanqin Liu et al.
AUSTRALIAN JOURNAL OF CHEMISTRY (2011)
Understanding and optimizing electrospray ionization techniques for proteomic analysis
Peter Liuni et al.
EXPERT REVIEW OF PROTEOMICS (2011)
Macromolecular NMR spectroscopy for the non-spectroscopist
Ann H. Kwan et al.
FEBS JOURNAL (2011)
Ions in Size-Selected Aqueous Nanodrops: Sequential Water Molecule Binding Energies and Effects of Water on Ion Fluorescence
William A. Donald et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Bound Anions Differentially Stabilize Multiprotein Complexes in the Absence of Bulk Solvent
Linjie Han et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Lysine-Specific Molecular Tweezers Are Broad-Spectrum Inhibitors of Assembly and Toxicity of Amyloid Proteins
Sharmistha Sinha et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Mapping a Noncovalent Protein-Peptide Interface by Top-Down FTICR Mass Spectrometry Using Electron Capture Dissociation
David J. Clarke et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2011)
Heme Binding in Gas-Phase Holo-Myoglobin Cations: Distal Becomes Proximal?
Atim A. Enyenihi et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2011)
Protein Conformation and Supercharging with DMSO from Aqueous Solution
Harry J. Sterling et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2011)
Electron Capture, Collision-Induced, and Electron Capture-Collision Induced Dissociation in Q-TOF
Valery G. Voinov et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2011)
Quantifying Protein-Fatty Acid Interactions Using Electrospray Ionization Mass Spectrometry
Lan Liu et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2011)
Ligand binding to distinct states diverts aggregation of an amyloid-forming protein
Lucy A. Woods et al.
NATURE CHEMICAL BIOLOGY (2011)
Gas-phase electrochemistry: Measuring absolute potentials and investigating ion and electron hydration
William A. Donald et al.
PURE AND APPLIED CHEMISTRY (2011)
Mass Spectrometry of Intact V-Type ATPases Reveals Bound Lipids and the Effects of Nucleotide Binding
Min Zhou et al.
SCIENCE (2011)
Multiple Soft Ionization of Gas-Phase Proteins and Swift Backbone Dissociation in Collisions with <= 99 eV Electrons
Roman A. Zubarev et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
A Method for Removing Effects of Nonspecific Binding on the Distribution of Binding Stoichiometries: Application to Mass Spectroscopy Data
Liat Shimon et al.
BIOPHYSICAL JOURNAL (2010)
Ion mobility mass spectrometry of proteins and protein assemblies
Charlotte Uetrecht et al.
CHEMICAL SOCIETY REVIEWS (2010)
Native MS: an 'ESI' way to support structure- and fragment-based drug discovery
Valerie Vivat Hannah et al.
FUTURE MEDICINAL CHEMISTRY (2010)
Evidence that Water Can Reduce the Kinetic Stability of Protein-Hydrophobic Ligand Interactions
Lan Liu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Weighing Photon Energies with Mass Spectrometry: Effects of Water on Ion Fluorescence
William A. Donald et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Probing the Hydrophobic Effect of Noncovalent Complexes by Mass Spectrometry
Claudia Bich et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2010)
Quantifying Labile Protein-Ligand Interactions Using Electrospray Ionization Mass Spectrometry
Amr El-Hawiet et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2010)
Effects of Buffer Loading for Electrospray Ionization Mass Spectrometry of a Noncovalent Protein Complex that Requires High Concentrations of Essential Salts
Harry J. Sterling et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2010)
Measuring the Extent and Width of Internal Energy Deposition in Ion Activation Using Nanocalorimetry
William A. Donald et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2010)
Nonspecific Interactions Between Proteins and Charged Biomolecules in Electrospray Ionization Mass Spectrometry
Nian Sun et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2010)
Elucidating the Site of Protein-ATP Binding by Top-Down Mass Spectrometry
Sheng Yin et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2010)
New Reagents for Increasing ESI Multiple Charging of Proteins and Protein Complexes
Shirley H. Lomeli et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2010)
Adding calorimetric data to decision making in lead discovery: a hot tip
John E. Ladbury et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Gas Phase Stabilization of Noncovalent Protein Complexes Formed by Electrospray Ionization
Dhanashri Bagal et al.
ANALYTICAL CHEMISTRY (2009)
Affinity Classification of Kinase Inhibitors by Mass Spectrometric Methods and Validation Using Standard IC50 Measurements
Matthias Conradin Jecklin et al.
ANALYTICAL CHEMISTRY (2009)
Solution-Phase Chelators for Suppressing Nonspecific Protein-Metal Interactions in Electrospray Mass Spectrometry
Jingxi Pan et al.
ANALYTICAL CHEMISTRY (2009)
Combined Charged Residue-Field Emission Model of Macromolecular Electrospray Ionization
Christopher J. Hogan et al.
ANALYTICAL CHEMISTRY (2009)
Ultraviolet Photodissociation: Developments towards Applications for Mass-Spectrometry-Based Proteomics
Tony Ly et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
Gas-Phase Unfolding and Disassembly Reveals Stability Differences in Ligand-Bound Multiprotein Complexes
Suk-Joon Hyung et al.
CHEMISTRY & BIOLOGY (2009)
Label-free determination of protein-ligand binding constants using mass spectrometry and validation using surface plasmon resonance and isothermal titration calorimetry
Matthias C. Jecklin et al.
JOURNAL OF MOLECULAR RECOGNITION (2009)
Hydrophobic Protein-Ligand Interactions Preserved in the Gas Phase
Lan Liu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Electron Ionization Dissociation of Singly and Multiply Charged Peptides
Y. M. Eva Fung et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
How to Deal with Weak Interactions in Noncovalent Complexes Analyzed by Electrospray Mass Spectrometry: Cyclopeptidic Inhibitors of the Nuclear Receptor Coactivator 1-STAT6
David Touboul et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2009)
Dynamics of Ions of Intact Proteins in the Orbitrap Mass Analyzer
Alexander Makarov et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2009)
Collisional Activation of Protein Complexes: Picking Up the Pieces
Justin L. P. Benesch
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2009)
Collision Induced Unfolding of Protein Ions in the Gas Phase Studied by Ion Mobility-Mass Spectrometry: The Effect of Ligand Binding on Conformational Stability
Jonathan T. S. Hopper et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2009)
Direct Analysis of Liquid Samples by Desorption Electrospray Ionization-Mass Spectrometry (DESI-MS)
Zhixin Miao et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2009)
ELECTROSPRAY: FROM IONS IN SOLUTION TO IONS IN THE GAS PHASE, WHAT WE KNOW NOW
Paul Kebarle et al.
MASS SPECTROMETRY REVIEWS (2009)
ULTRAVIOLET PHOTOFRAGMENTATION OF BIOMOLECULAR IONS
James P. Reilly
MASS SPECTROMETRY REVIEWS (2009)
The major toxin from the Australian Common Brown Snake is a hexamer with unusual gas-phase dissociation properties
J. Andrew Aquilina
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2009)
Surface-induced dissociation of peptides and protein complexes in a quadrupole/Time-of-Flight mass spectrometer
Asiri S. Galhena et al.
ANALYTICAL CHEMISTRY (2008)
Mass Spectrometry for Studying the Interaction between Small Molecules and Proteins
Enrique Calvo et al.
Current Proteomics (2008)
Ion mobility-mass spectrometry
Abu B. Kanu et al.
JOURNAL OF MASS SPECTROMETRY (2008)
Elucidating the intermolecular interactions within a desolvated protein-ligand complex. An experimental and computational study
Elena N. Kitova et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Electron capture by a hydrated gaseous peptide: Effects of water on fragmentation and molecular survival
James S. Prell et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Mass spectrometry of protein-ligand complexes: Enhanced gas-phase stability of ribonuclease-nucleotide complexes
Sheng Yin et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2008)
Stepwise evolution of protein native structure with electrospray into the gas phase, 10-12 to 102 S
Kathrin Breuker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Extraction of ions from solutions under atmospheric pressure as a method for mass spectrometric analysis of bioorganic compounds
M. L. Alexandrov et al.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2008)
Micelles protect membrane complexes from solution to vacuum
Nelson P. Barrera et al.
SCIENCE (2008)
Direct screening of natural product extracts using mass spectrometry
Hoan Vu et al.
JOURNAL OF BIOMOLECULAR SCREENING (2008)
Stoichiometry and localization of the stator subunits E and G in Thermus thermophilus H+-ATPase/synthase
Olga Esteban et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The future of high-throughput screening
Lorenz M. Mayr et al.
JOURNAL OF BIOMOLECULAR SCREENING (2008)
Method for identifying nonspecific protein-protein interactions in nanoelectrospray ionization mass Spectrometry
Jiangxiao Sun et al.
ANALYTICAL CHEMISTRY (2007)
Protein complexes in the gas phase: Technology for structural genomics and proteomics
Justin L. P. Benesch et al.
CHEMICAL REVIEWS (2007)
Ligand-induced monomerization of Allochromatium vinosum cytochrome c' studied using native mass spectrometry and fluorescence resonance energy transfer
Toon H. Evers et al.
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2007)
Combined mass spectrometry and dynamic chemistry approach to identify metalloenzyme inhibitors
Benoft M. R. Lienard et al.
CHEMMEDCHEM (2007)
Method for stabilizing protein-ligand complexes in nanoelectrospray ionization mass spectrometry
Jiangxiao Sun et al.
ANALYTICAL CHEMISTRY (2007)
A novel surface-induced dissociation instrument for ion mobility-time-of-flight mass spectrometry
Wenjian Sun et al.
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY (2007)
Symmetrical gas-phase dissociation of noncovalent protein complexes via surface collisions
Christopher M. Jones et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Direct observation of oligomeric species formed in the early stages of amyloid fibril formation using electrospray ionisation mass spectrometry
Andrew M. Smith et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Top-down ESI-ECD-FT-ICR mass spectrometry localizes noncovalent protein-ligand binding sites
Yongming Xie et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Aspects of native proteins are retained in vacuum
Brandon T. Ruotolo et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2006)
Dynamic combinatorial chemistry
Peter T. Corbett et al.
CHEMICAL REVIEWS (2006)
Opinion - Drug-target residence time and its implications for lead optimization
Robert A. Copeland et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
A deconvolution method for the separation of specific versus nonspecific interactions in noncovalent protein-ligand complexes analyzed by ESI-FT-ICR mass spectrometry
Thorsten Daubenfeld et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2006)
Direct screening of a dynamic combinatorial library using mass spectrometry
Sally-Ann Poulsen
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2006)
Applications of ESI-MS in drug discovery: interrogation of noncovalent complexes
Steven A. Hofstadler et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Method for distinguishing specific from nonspecific protein-ligand complexes in nanoelectrospray ionization mass spectrometry
Jiangxiao Sun et al.
ANALYTICAL CHEMISTRY (2006)
Temperature dependence and thermodynamics of Klenow polymerase binding to primed-template DNA
K Datta et al.
BIOPHYSICAL JOURNAL (2006)
Blackbody infrared radiative dissociation of nonspecific protein-carbohydrate complexes produced by nanoelectrospray ionization: The nature of the noncovalent interactions
WJ Wang et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2005)
Clear evidence of fluorescence resonance energy transfer in gas-phase ions
M Dashtiev et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2005)
Nonspecific protein-carbohydrate complexes produced by nanoelectrospray ionization. Factors influencing their formation and stability
WJ Wang et al.
ANALYTICAL CHEMISTRY (2005)
The role of electron capture dissociation in biomolecular analysis
HJ Cooper et al.
MASS SPECTROMETRY REVIEWS (2005)
The salt-dependence of a protein-ligand interaction: Ion-protein binding energetics
TT Waldron et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Decharging of globular proteins and protein complexes in electrospray
MI Catalina et al.
CHEMISTRY-A EUROPEAN JOURNAL (2005)
Determination of protein-ligand association thermochemistry using variable-temperature nanoelectrospray mass spectrometry
R Daneshfar et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Observation of an intact noncovalent homotrimer of detergent-solubilized rat microsomal glutathione transferase-1 by electrospray mass spectrometry
J Lengqvist et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Structural change in response to ligand binding
MG McCammon et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2004)
Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides derived from 4-isothiocyanato-benzolamide
A Cecchi et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)
Determination of ligand-protein dissociation constants by electrospray mass spectrometry-based diffusion measurements
SM Clark et al.
ANALYTICAL CHEMISTRY (2004)
Fragment-based drug discovery
DA Erlanson et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Drug binding revealed by tandem mass spectrometry of a protein-micelle complex
LL Ilag et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Mass spectrometry sampling under ambient conditions with desorption electrospray ionization
Z Takáts et al.
SCIENCE (2004)
Tandem mass spectrometry defines the stoichiometry and quaternary structural arrangement of tryptophan molecules in the multiprotein complex TRAP
MG McCammon et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Features of the ESI mechanism that affect the observation of multiply charged noncovalent protein complexes and the determination of the association constant by the titration method
M Peschke et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2004)
Bioactive recognition sites may not be energetically preferred in protein-carbohydrate complexes in the gas phase
WJ Wang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Influence of solution and gas phase processes on protein-carbohydrate binding affinities determined by nanoelectrospray Fourier transform ion cyclotron resonance mass spectrometry
WJ Wang et al.
ANALYTICAL CHEMISTRY (2003)
Use of a microchip device coupled with mass spectrometry for ligand screening of a multi-protein target
CA Keetch et al.
ANALYTICAL CHEMISTRY (2003)
Preparing protein microarrays by soft-landing of mass-selected ions
Z Ouyang et al.
SCIENCE (2003)
Quantitative determination of noncovalent binding interactions using automated nanoelectrospray mass spectrometry
S Zhang et al.
ANALYTICAL CHEMISTRY (2003)
Effect of buffer cations and of H3O+ on the charge states of native proteins.: Significance to determinations of stability constants of protein complexes
UH Verkerk et al.
JOURNAL OF MASS SPECTROMETRY (2003)
Thermal dissociation of multimeric protein complexes by using nanoelectrospray mass spectrometry
JLP Benesch et al.
ANALYTICAL CHEMISTRY (2003)
Measurement of dissociation constants of inhibitors binding to Src SH2 domain protein by non-covalent electrospray ionization mass spectrometry
SWA Bligh et al.
JOURNAL OF MOLECULAR RECOGNITION (2003)
Influence of response factors on determining equilibrium association constants of non-covalent complexes by electrospray ionization mass spectrometry
V Gabelica et al.
JOURNAL OF MASS SPECTROMETRY (2003)
Mass spectrometric determination of association constants of adenylate kinase with two noncovalent inhibitors
JM Daniel et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2003)
Using nondenaturing mass spectrometry to detect fortuitous ligands in orphan nuclear receptors
N Potier et al.
PROTEIN SCIENCE (2003)
Origin of asymmetric charge partitioning in the dissociation of gas-phase protein homodimers
JC Jurchen et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Coulomb fission -: Rayleigh jets from levitated microdroplets
D Duft et al.
NATURE (2003)
Native electron capture dissociation for the structural characterization of noncovalent interactions in native cytochrome c
K Breuker et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
Retention of bioactive ligand conformation in a gaseous protein-trisaccharide complex
EN Kitova et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
Fourier transform-ion cyclotron resonance mass spectrometric resolution, identification, and screening of non-covalent complexes of Hck Src homology 2 domain receptor and ligands from a 324-member peptide combinatorial library
M Wigger et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2002)
Thermal dissociation of protein-oligosaccharide complexes in the gas phase: Mapping the intrinsic intermolecular interactions
EN Kitova et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
A tandem mass spectrometer for improved transmission and analysis of large macromolecular assemblies
F Sobott et al.
ANALYTICAL CHEMISTRY (2002)
High-throughput crystallography for lead discovery in drug design
TL Blundell et al.
NATURE REVIEWS DRUG DISCOVERY (2002)
Electron capture dissociation of weakly bound polypeptide polycationic complexes
KF Haselmann et al.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2002)
Towards an understanding of the mechanism of electron-capture dissociation: a historical perspective and modern ideas
RA Zubarev et al.
EUROPEAN JOURNAL OF MASS SPECTROMETRY (2002)
Optimization of a matrix-assisted laser desorption ionization-ion mobility-surface-induced dissociation-orthogonal-time-of-flight mass spectrometer:: simultaneous acquisition of multiple correlated MS1 and MS2 spectra
EG Stone et al.
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY (2001)
Monitoring structural changes of proteins in an ion trap over ∼10-200 ms:: Unfolding transitions in cytochrome c ions
ER Badman et al.
ANALYTICAL CHEMISTRY (2001)
Gas-phase dissociation of hemoglobin
C Versluis et al.
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY (2001)
Stabilization of gas-phase noncovalent macromolecular complexes in electrospray mass spectrometry using aqueous triethylammonium bicarbonate buffer
D Lemaire et al.
ANALYTICAL CHEMISTRY (2001)
Mass spectrometry as a novel approach to probe cooperativity in multimeric enzymatic systems
H Rogniaux et al.
ANALYTICAL BIOCHEMISTRY (2001)
Supercharged protein and peptide lone formed by electrospray ionization
AT Iavarone et al.
ANALYTICAL CHEMISTRY (2001)
The effect of the source pressure on the abundance of ions of noncovalent protein assemblies in an electrospray ionization orthogonal time-of-flight instrument
N Tahallah et al.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY (2001)
HIV-1 protease inhibitors: Enthalpic versus entropic optimization of the binding affinity
A Velazquez-Campoy et al.
BIOCHEMISTRY (2000)
The Protein Data Bank
HM Berman et al.
NUCLEIC ACIDS RESEARCH (2000)
A fully integrated monolithic microchip electrospray device for mass spectrometry
GA Schultz et al.
ANALYTICAL CHEMISTRY (2000)