4.4 Review

How to express the antioxidant properties of substances properly?

Journal

CHEMICAL PAPERS
Volume 75, Issue 12, Pages 6157-6167

Publisher

SPRINGER INT PUBL AG
DOI: 10.1007/s11696-021-01799-1

Keywords

Antioxidant properties; IC50; Inhibition percent; AE parameter; Standard antioxidant

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This paper reviews the common ways of expressing antioxidant activities, highlighting the issue of incompatible and unreasonable interpretation of results. It emphasizes the importance of studying antioxidant properties in various fields, especially in the advancement of medicine for the detection and treatment of serious diseases in the future.
Oxidative stress, associated with an imbalance between the oxidants (reactive oxygen species) and the antioxidants in the body, contributes to the development of many diseases. The body's fight against reactive oxygen species is supported by antioxidants. Nowadays, there are too many analytical methods, but there is no one universal technique for assessing antioxidant properties. Moreover, the applied different ways of expressing the results lead to their incompatibility and unreasonable interpretation. The paper is a literature review concerning the most frequent ways of antioxidant activities expression and for an easy and universal method of the obtained results discussion. This paper is an attempt to point out their disadvantages and advantages. The manuscript can support the searching interpretation of the obtained results which will be a good tool for the development of a number of fields, especially medicine what can help in the future detection and treatment of many serious diseases. Graphic abstract

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