4.5 Review

Multidrug efflux pumps and their role in antibiotic and antiseptic resistance: a pharmacodynamic perspective

Related references

Note: Only part of the references are listed.
Review Microbiology

Optimization of a novel series of pyranopyridine RND efflux pump inhibitors

Zachary Aron et al.

CURRENT OPINION IN MICROBIOLOGY (2016)

Article Chemistry, Multidisciplinary

A new Pseudomonas quinolone signal (PQS) binding partner: MexG

James T. Hodgkinson et al.

CHEMICAL SCIENCE (2016)

Article Biochemistry & Molecular Biology

The pseudo-atomic structure of an RND-type tripartite multidrug efflux pump

Dijun Du et al.

BIOLOGICAL CHEMISTRY (2015)

Article Biochemistry & Molecular Biology

Structure-activity relationships of a novel pyranopyridine series of Gram-negative bacterial efflux pump inhibitors

Son T. Nguyen et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2015)

Review Microbiology

The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative Bacteria

Xian-Zhi Li et al.

CLINICAL MICROBIOLOGY REVIEWS (2015)

Article Multidisciplinary Sciences

Microspectrometric insights on the uptake of antibiotics at the single bacterial cell level

Bertrand Cinquin et al.

SCIENTIFIC REPORTS (2015)

Review Microbiology

Interaction of antibacterial compounds with RND efflux pumps in Pseudomonas aeruginosa

Juerg Dreier et al.

FRONTIERS IN MICROBIOLOGY (2015)

Article Microbiology

RND-type drug efflux pumps from Gram-negative bacteria: molecular mechanism and inhibition

Henrietta Venter et al.

FRONTIERS IN MICROBIOLOGY (2015)

Article Microbiology

Recent advances toward a molecular mechanism of efflux pump inhibition

Timothy J. Opperman et al.

FRONTIERS IN MICROBIOLOGY (2015)

Review Microbiology

Structural basis of RND-type multidrug exporters

Akihito Yamaguchi et al.

FRONTIERS IN MICROBIOLOGY (2015)

Review Microbiology

Molecular mechanisms of antibiotic resistance

Jessica M. A. Blair et al.

NATURE REVIEWS MICROBIOLOGY (2015)

Review Biophysics

Bacterial Multidrug Efflux Transporters

Jared A. Delmar et al.

ANNUAL REVIEW OF BIOPHYSICS, VOL 43 (2014)

Article Multidisciplinary Sciences

Structure of the AcrAB-TolC multidrug efflux pump

Dijun Du et al.

NATURE (2014)

Article Biochemistry & Molecular Biology

Search for new tools to combat Gram-negative resistant bacteria among amine derivatives of 5-arylidenehydantoin

Jadwiga Handzlik et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2013)

Review Chemistry, Medicinal

RND Efflux Pumps: Structural Information Translated into Function and Inhibition Mechanisms

Paolo Ruggerone et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2013)

Article Multidisciplinary Sciences

Multidrug binding properties of the AcrB efflux pump characterized by molecular dynamics simulations

Attilio V. Vargiu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Multidisciplinary Sciences

Conserved small protein associates with the multidrug efflux pump AcrB and differentially affects antibiotic resistance

Errett C. Hobbs et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Microbiology

Broad-specificity efflux pumps and their role in multidrug resistance of Gram-negative bacteria

Hiroshi Nikaido et al.

FEMS MICROBIOLOGY REVIEWS (2012)

Review Chemistry, Multidisciplinary

Quorum Sensing in Gram-Negative Bacteria: Small-Molecule Modulation of AHL and Al-2 Quorum Sensing Pathways

Warren R. J. D. Galloway et al.

CHEMICAL REVIEWS (2011)

Article Chemistry, Medicinal

Amine-alkyl derivatives of hydantoin: New tool to combat resistant bacteria

Jadwiga Handzlik et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2011)

Review Biochemistry & Molecular Biology

Strategies for bypassing the membrane barrier in multidrug resistant Gram-negative bacteria

Jean-Michel Bolla et al.

FEBS LETTERS (2011)

Article Critical Care Medicine

Managing antimicrobial resistance in intensive care units

Tejal N. Gandhi et al.

CRITICAL CARE MEDICINE (2010)

Review Chemistry, Medicinal

Efflux Pumps of Gram-Negative Bacteria, a New Target for New Molecules

Jean-Marie Pages et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2010)

Article Public, Environmental & Occupational Health

Progress and Challenges in Implementing the Research on ESKAPE Pathogens

Louis B. Rice

INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY (2010)

News Item Biotechnology & Applied Microbiology

The antibacterial lead discovery challenge

Dan Jones

NATURE REVIEWS DRUG DISCOVERY (2010)

Review Microbiology

Quorum sensing in bacterial virulence

L. Caetano M. Antunes et al.

MICROBIOLOGY-SGM (2010)

Article Multidisciplinary Sciences

Mechanism of recognition of compounds of diverse structures by the multidrug efflux pump AcrB of Escherichia coli

Yumiko Takatsuka et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Microbiology

Geraniol Restores Antibiotic Activities against Multidrug-Resistant Isolates from Gram-Negative Species

Vannina Lorenzi et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)

Review Biochemistry & Molecular Biology

Mechanisms of drug efflux and strategies to combat them: Challenging the efflux pump of Gram-negative bacteria

Jean-Marie Pages et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2009)

Article Immunology

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

Helen W. Boucher et al.

CLINICAL INFECTIOUS DISEASES (2009)

Review Microbiology

The clinical consequences of antimicrobial resistance

Louis B. Rice

CURRENT OPINION IN MICROBIOLOGY (2009)

Review Microbiology

Structure, function and inhibition of RND efflux pumps in Gram-negative bacteria: an update

Jessica M. A. Blair et al.

CURRENT OPINION IN MICROBIOLOGY (2009)

Review Multidisciplinary Sciences

Quorum sensing and social networking in the microbial world

Steve Atkinson et al.

JOURNAL OF THE ROYAL SOCIETY INTERFACE (2009)

Article Multidisciplinary Sciences

A coordinated network of transporters with overlapping specificities provides a robust survival strategy

Nir Tal et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Review Pharmacology & Pharmacy

Promising Therapy of XDR-TB/MDR-TB with Thioridazine an Inhibitor of Bacterial Efflux Pumps

L. Amaral et al.

CURRENT DRUG TARGETS (2008)

Review Pharmacology & Pharmacy

Membrane Permeability and Regulation of Drug Influx and Efflux in Enterobacterial Pathogens

Anne Davin-Regli et al.

CURRENT DRUG TARGETS (2008)

Article Infectious Diseases

Potential of old-generation antibiotics to address current need for new antibiotics

Matthew E. Falagas et al.

EXPERT REVIEW OF ANTI-INFECTIVE THERAPY (2008)

Article Infectious Diseases

Thioridazine and chlorpromazine inhibition of ethidium bromide efflux in Mycobacterium avium and Mycobacterium smegmatis

Liliana Rodrigues et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2008)

Article Infectious Diseases

Treatment of health-care-associated infections caused by Gram-negative bacteria: a consensus statement

Ian Chopra et al.

LANCET INFECTIOUS DISEASES (2008)

Review Microbiology

The porin and the permeating antibiotic: a selective diffusion barrier in Gram-negative bacteria

Jean-Marie Pages et al.

NATURE REVIEWS MICROBIOLOGY (2008)

Review Infectious Diseases

Measuring the impact of multidrug resistance in nosocomial infection

Stijn Blot et al.

CURRENT OPINION IN INFECTIOUS DISEASES (2007)

Article Infectious Diseases

Antibiotic efflux pumps in Gram-negative bacteria:: the inhibitor response strategy

Abdallah Mahamoud et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2007)

Review Infectious Diseases

Pandrug-resistant Gram-negative bacteria: the dawn of the post-antibiotic era?

Matthew E. Falagas et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2007)

Review Biochemistry & Molecular Biology

Molecular mechanisms of antibacterial multidrug resistance

Michael N. Alekshun et al.

Review Biotechnology & Applied Microbiology

Waltzing transporters and 'the dance macabre' between humans and bacteria

Olga Lomovskaya et al.

NATURE REVIEWS DRUG DISCOVERY (2007)

Article Multidisciplinary Sciences

Crystal structures of a multidrug transporter reveal a functionally rotating mechanism

Satoshi Murakami et al.

NATURE (2006)

Article Multidisciplinary Sciences

Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism

Markus A. Seeger et al.

SCIENCE (2006)

Review Microbiology

Multidrug-resistance efflux pumps - not just for resistance

Laura J. V. Piddock

NATURE REVIEWS MICROBIOLOGY (2006)

Review Pharmacology & Pharmacy

Practical applications and feasibility of efflux pump inhibitors in the clinic - A vision for applied use

O Lomovskaya et al.

BIOCHEMICAL PHARMACOLOGY (2006)

Review Infectious Diseases

Efflux-mediated antimicrobial resistance

K Poole

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2005)

Review Pharmacology & Pharmacy

Mechanisms of antimicrobial peptide action and resistance

MR Yeaman et al.

PHARMACOLOGICAL REVIEWS (2003)

Review Microbiology

Molecular basis of bacterial outer membrane permeability revisited

H Nikaido

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2003)

Article Multidisciplinary Sciences

Crystal structure of bacterial multidrug efflux transporter AcrB

S Murakami et al.

NATURE (2002)

Article Biotechnology & Applied Microbiology

Active efflux, a common mechanism for biocide and antibiotic resistance

SB Levy

JOURNAL OF APPLIED MICROBIOLOGY (2002)

Article Microbiology

AcrD of Escherichia coli is an aminoglycoside efflux pump

EY Rosenberg et al.

JOURNAL OF BACTERIOLOGY (2000)