Journal
CELL METABOLISM
Volume 33, Issue 6, Pages 1069-1071Publisher
CELL PRESS
DOI: 10.1016/j.cmet.2021.05.011
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Funding
- NIH [AI40646, AI44828, AI23323, CA231620]
- ALSAC
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Jiao et al. discovered a novel mechanism of quality control where damaged mitochondria move to the plasma membrane and are left behind the trailing edge of migrating cells, which is essential for maintaining cellular and tissue homeostasis.
The repair and removal of damaged mitochondria is essential for sustaining cellular and tissue homeostasis. Now in Cell, Jiao et al. (2021) describe a novel mechanism of such quality control in which damaged mitochondria move to the plasma membrane where they are packaged'' and left behind the trailing edge of migrating cells.
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