The deep population history of northern East Asia from the Late Pleistocene to the Holocene

Northern East Asia was inhabited by modern humans as early as 40 thousand years ago (ka), as demonstrated by the Tianyuan individual. Using genome-wide data obtained from 25 individuals dated to 33.6-3.4 ka from the Amur region, we show that Tianyuan-related ancestry was widespread in northern East Asia before the Last Glacial Maximum (LGM). At the close of the LGM stadial, the earliest northern East Asian appeared in the Amur region, and this population is basal to ancient northern East Asians. Human populations in the Amur region have maintained genetic continuity from 14 ka, and these early inhabitants represent the closest East Asian source known for Ancient Paleo-Siberians. We also observed that EDAR V370A was likely to have been elevated to high frequency after the LGM, suggesting the possible timing for its selection. This study provides a deep look into the population dynamics of northern East Asia.

Automated summary

Modern humans have been living in Northern East Asia as early as 40,000 years ago, as demonstrated by the Tianyuan individual. The genetic continuity of human populations in the Amur region has been maintained since 14ka, representing the closest East Asian source known for Ancient Paleo-Siberians. This study provides insights into the population dynamics of Northern East Asia.