Nano-magnetic-iron Oxides@choline Acetate as a Heterogeneous Catalyst for the Synthesis of 1,2,3-Triazoles

In this research, four cholines supported on core-shell iron oxides, Fe2O3@MgO@Ch center dot OAc (choline acetate), Fe2O3@MgO@Ch center dot OH (choline hydroxide), Fe3O4@Ch.OAc, Fe3O4@Ch center dot OH, were synthesized. The synthesized catalysts were tested in 1,2,3-triazoles synthesis by the reaction of nitromethane, aldehyde, and benzyl azide in EtOH as a green solvent. Among four synthesized heterogeneous catalysts, the Fe2O3@MgO@ch center dot OAc showed superior catalytic activity for the reaction and afforded the desired triazoles in good isolated yields under mild reaction conditions.

Automated summary

In this research, four choline-supported iron oxide catalysts were synthesized and tested in the synthesis of 1,2,3-triazoles. Among these catalysts, Fe2O3@MgO@ch center dot OAc showed superior catalytic activity and provided good isolated yields of the desired triazoles under mild reaction conditions.