Journal
CARBOHYDRATE POLYMERS
Volume 262, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2021.117962
Keywords
Polysaccharide; Triple helix conformation; Congo red; Biological activities; Structure-function relationship
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Funding
- National Natural Science Foundation of China [32072173]
- Project of Tianjin Science and Technology Program [19PTSYJC00040]
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This review specifically examines the formation mechanisms, structure-activity relationships, and analytical methods for triple-helix polysaccharides. The insights provided can be valuable for exploring the biological activities of polysaccharides and their applications in the food and pharmaceutical industries.
Triple helix conformation of polysaccharides is generally believed to be associated with their biological activities. However, the formation mechanisms and analytical methods for the triple helix polysaccharides, to our best knowledge, have not been systematically investigated. This article reviews specifically the literature on the formation and characterization of triple-helix polysaccharides. The formation mechanisms and related structuralconformation-bioactivity relationships are discussed; various analytical methods for characterizing triple-helix polysaccharides are summarized. This review devotes to a better understanding of the formation of polysaccharides based triple-helix structure and related analytical methods. These could provide some insights and inspirations for their applications in both food and pharmaceutical industries.
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