4.5 Review

Cell-to-cell contact-mediated regulation of tumor behavior in the tumor microenvironment

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

Emerging trends in chromatin remodeler plasticity in mesenchymal stromal cell function

Sayan Chakraborty et al.

Summary: The integration of epigenetic regulation with transcriptional and cell signaling machinery plays a crucial role in determining tissue resident adult pluripotent mesenchymal stem/stromal cell (MSC) activity, lineage commitment, and immunomodulation. Histone modifying enzymes and chromatin remodeling complexes are central features influencing gene regulation and tissue identity establishment in MSCs. Modulation of transcription factor expression gradient and flexibility of chromatin architecture are exciting approaches to regulate MSC activity.

FASEB JOURNAL (2021)

Review Cell Biology

Cancer-Associated Fibroblasts Suppress Cancer Development: The Other Side of the Coin

Zhanhuai Wang et al.

Summary: Cancer-associated fibroblasts (CAFs) are heterogeneous cells in the tumor microenvironment that can both promote and inhibit tumor development. The activation state of CAFs can vary, leading to different roles in early-stage and advanced-stage cancer. Understanding the diverse functions and origins of CAFs is crucial for developing precise cancer therapies.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Article Oncology

Stomatin-Mediated Inhibition of the Akt Signaling Axis Suppresses Tumor Growth

Nor Idayu A. Rahman et al.

Summary: Stromal-induced stomatin expression in prostate cancer cells suppresses tumor growth by inhibiting the Akt signaling axis, with clinical relevance shown in decreased stomatin levels in high Gleason score prostate cancer samples and higher recurrence rates post-operation.

CANCER RESEARCH (2021)

Review Oncology

Flotillin membrane domains in cancer

Cecile Gauthier-Rouviere et al.

CANCER AND METASTASIS REVIEWS (2020)

Review Oncology

Tunneling Nanotubes and Tumor Microtubes in Cancer

Cora Roehlecke et al.

CANCERS (2020)

Review Biochemistry & Molecular Biology

Cytokines and Chemokines as Mediators of Prostate Cancer Metastasis

Timothy O. Adekoya et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Chemistry, Medicinal

SFPH proteins as therapeutic targets for a myriad of diseases

Dong Wang et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2020)

Article Urology & Nephrology

African American Specific Gene Panel Predictive of Poor Prostate Cancer Outcome

Michelle I. Echevarria et al.

JOURNAL OF UROLOGY (2019)

Review Biochemistry & Molecular Biology

Connexins in cancer: bridging the gap to the clinic

Trond Aasen et al.

ONCOGENE (2019)

Article Oncology

Stomatin plays a suppressor role in non-small cell lung cancer metastasis

Huaying An et al.

CHINESE JOURNAL OF CANCER RESEARCH (2019)

Review Biochemistry & Molecular Biology

Fibroblasts in the Tumor Microenvironment: Shield or Spear?

Twana Alkasalias et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Biochemistry & Molecular Biology

Epithelial membrane protein 1 promotes tumor metastasis by enhancing cell migration via copine-III and Rac1

Mohammad Khusni B. Ahmat Amin et al.

ONCOGENE (2018)

Review Oncology

Notch Signaling in the Tumor Microenvironment

Olivier Meurette et al.

CANCER CELL (2018)

Article Cardiac & Cardiovascular Systems

Cadherin-11 as a regulator of valve myofibroblast mechanobiology

Meghan A. Bowler et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2018)

Review Biochemistry & Molecular Biology

Vasculogenic mimicry signaling revisited: focus on non-vascular VE-cadherin

Daniel Delgado-Bellido et al.

MOLECULAR CANCER (2017)

Article Multidisciplinary Sciences

Stomatin modulates the activity of the Anion Exchanger 1 (AE1, SLC4A1)

Sandrine Genetet et al.

SCIENTIFIC REPORTS (2017)

Review Immunology

Immune regulation by glucocorticoids

Derek W. Cain et al.

NATURE REVIEWS IMMUNOLOGY (2017)

Article Biochemistry & Molecular Biology

Astrocytes promote glioma invasion via the gap junction protein connexin43

W. C. Sin et al.

ONCOGENE (2016)

Article Multidisciplinary Sciences

Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer

Qing Chen et al.

NATURE (2016)

Article Biochemistry & Molecular Biology

Enhanced Adhesion of Stromal Cells to Invasive Cancer Cells Regulated by Cadherin 11

Kathleen M. McAndrews et al.

ACS CHEMICAL BIOLOGY (2015)

Article Hematology

Gap Junction Coupling Is Required for Tumor Cell Migration Through Lymphatic Endothelium

Natalie O. Karpinich et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2015)

Article Multidisciplinary Sciences

Brain tumour cells interconnect to a functional and resistant network

Matthias Osswald et al.

NATURE (2015)

Article Biochemistry & Molecular Biology

Connexin 43 Suppresses Tumor Angiogenesis by Down-Regulation of Vascular Endothelial Growth Factor via Hypoxic-Induced Factor-1α

Wei-Kuang Wang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)

Article Biochemistry & Molecular Biology

Exosome Transfer from Stromal to Breast Cancer Cells Regulates Therapy Resistance Pathways

Mirjam C. Boelens et al.

Review Oncology

Targeting PI3K/Akt/mTOR signaling in cancer

Camillo Porta et al.

FRONTIERS IN ONCOLOGY (2014)

Article Biochemistry & Molecular Biology

Stomatin interacts with GLUT1/SLC2A1, band 3/SLC4A1, and aquaporin-1 in human erythrocyte membrane domains

Stefanie Rungaldier et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2013)

Article Biochemistry & Molecular Biology

A stomatin dimer modulates the activity of acid-sensing ion channels

Janko Brand et al.

EMBO JOURNAL (2012)

Review Cell Biology

Stomatin-domain proteins

Liudmilla Lapatsina et al.

EUROPEAN JOURNAL OF CELL BIOLOGY (2012)

Article Cell Biology

The tumor microenvironment at a glance

Frances R. Balkwill et al.

JOURNAL OF CELL SCIENCE (2012)

Article Anatomy & Morphology

Epithelial Membrane Protein 1 Inhibits Human Spinal Chondrocyte Differentiation

Zhi-Yong Li et al.

ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY (2011)

Review Biochemistry & Molecular Biology

Hallmarks of Cancer: The Next Generation

Douglas Hanahan et al.

Article Biochemistry & Molecular Biology

Copine-III interacts with ErbB2 and promotes tumor cell migration

C. Heinrich et al.

ONCOGENE (2010)

Article Cell Biology

Bacteria-Induced Gap Junctions in Tumors Favor Antigen Cross-Presentation and Antitumor Immunity

Fabiana Saccheri et al.

SCIENCE TRANSLATIONAL MEDICINE (2010)

Review Oncology

Eph receptors and ephrins in cancer: bidirectional signalling and beyond

Elena B. Pasquale

NATURE REVIEWS CANCER (2010)

Review Biochemistry & Molecular Biology

Molecular components of the adherens junction

Carien M. Niessen et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2008)

Review Biochemistry & Molecular Biology

Eph-ephrin bidirectional signaling in physiology and disease

Elena B. Pasquale

Review Biochemistry & Molecular Biology

Microenvironmental regulation of E-cadherin-mediated adherens junctions

Klaudia Giehl et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2008)

Review Cell Biology

Nectins and nectin-like molecules: roles in contact inhibition of cell movement and proliferation

Yoshimi Takai et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)

Review Cell Biology

The SPFH domain-containing proteins: more than lipid raft markers

Duncan T. Browman et al.

TRENDS IN CELL BIOLOGY (2007)

Article Genetics & Heredity

Anatomic demarcation by positional variation in fibroblast gene expression programs

John L. Rinn et al.

PLOS GENETICS (2006)

Article Biochemistry & Molecular Biology

Epithelial membrane proteins induce membrane blebbing and interact with the P2X7 receptor C terminus

HL Wilson et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1

N Fujita et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)