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A. Chaves-Perez et al.
ONCOGENE (2013)
Curcumin reverses the epithelial-mesenchymal transition of pancreatic cancer cells by inhibiting the Hedgehog signaling pathway
Xiao-Dong Sun et al.
ONCOLOGY REPORTS (2013)
DCLK1 Regulates Pluripotency and Angiogenic Factors via microRNA-Dependent Mechanisms in Pancreatic Cancer
Sripathi M. Sureban et al.
PLOS ONE (2013)
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Anke Van den Broeck et al.
PLOS ONE (2013)
Activation of the sonic hedgehog signaling pathway occurs in the CD133 positive cells of mouse liver cancer Hepa 1-6 cells
Kuo-Shyang Jeng et al.
ONCOTARGETS AND THERAPY (2013)
Arsenic trioxide inhibits viability of pancreatic cancer stem cells in culture and in a xenograft model via binding to SHH-Gli
Jin-bin Han et al.
ONCOTARGETS AND THERAPY (2013)
Genistein decreases the breast cancer stem-like cell population through Hedgehog pathway
Panhong Fan et al.
STEM CELL RESEARCH & THERAPY (2013)
EZH2 Is Required for Breast and Pancreatic Cancer Stem Cell Maintenance and Can Be Used as a Functional Cancer Stem Cell Reporter
Lilian E. van Vlerken et al.
STEM CELLS TRANSLATIONAL MEDICINE (2013)
Cytoplasmic expression of LGR5 in pancreatic adenocarcinoma
Nobumasa Mizuno et al.
FRONTIERS IN PHYSIOLOGY (2013)
LGR5 is expressed by Ewing sarcoma and potentiates Wnt/beta-catenin signaling
Christopher A. Scannell et al.
FRONTIERS IN ONCOLOGY (2013)
Mechanisms of chemoresistance in cancer stem cells
Lissa Nurrul Abdullah et al.
CLINICAL AND TRANSLATIONAL MEDICINE (2013)
Human pancreatic adenocarcinoma contains a side population resistant to gemcitabine
Anke Van den Broeck et al.
BMC CANCER (2012)
Differential expression of microRNAs during melanoma progression: miR-200c, miR-205 and miR-211 are downregulated in melanoma and act as tumour suppressors
Y. Xu et al.
BRITISH JOURNAL OF CANCER (2012)
Metastatic Colonization Requires the Repression of the Epithelial-Mesenchymal Transition Inducer Prrx1
Oscar H. Ocana et al.
CANCER CELL (2012)
Hyaluronan Synthase HAS2 Promotes Tumor Progression in Bone by Stimulating the Interaction of Breast Cancer Stem-Like Cells with Macrophages and Stromal Cells
Hiroshi Okuda et al.
CANCER RESEARCH (2012)
Curcumin Analogue CDF Inhibits Pancreatic Tumor Growth by Switching on Suppressor microRNAs and Attenuating EZH2 Expression
Bin Bao et al.
CANCER RESEARCH (2012)
EMT and Dissemination Precede Pancreatic Tumor Formation
Andrew D. Rhim et al.
CELL (2012)
Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness
Enza Lonardo et al.
CELL CYCLE (2012)
Genistein Inhibits Cell Growth and Induces Apoptosis Through Up-regulation of miR-34a in Pancreatic Cancer Cells
Jun Xia et al.
CURRENT DRUG TARGETS (2012)
Pancreatic Carcinoma Cell Lines Reflect Frequency and Variability of Cancer Stem Cell Markers in Clinical Tissue
S. Buenger et al.
EUROPEAN SURGICAL RESEARCH (2012)
Stem cells as the root of pancreatic ductal adenocarcinoma
Anamaria Balic et al.
EXPERIMENTAL CELL RESEARCH (2012)
Identification of Pancreatic Cancer Stem Cells and Selective Toxicity of Chemotherapeutic Agents
Rama Adikrisna et al.
GASTROENTEROLOGY (2012)
Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics
Su-Ni Tang et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
Expression and role of nestin in human cervical intraepithelial neoplasia and cervical cancer
Atsuki Sato et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2012)
Inhibition of hedgehog signaling depresses self-renewal of pancreatic cancer stem cells and reverses chemoresistance
Feng-Ting Huang et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2012)
Aldehyde dehydrogenase 1A1 confers intrinsic and acquired resistance to gemcitabine in human pancreatic adenocarcinoma MIA PaCa-2 cells
Hong-Quan Duong et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2012)
CXCL12/CXCR4 Protein Signaling Axis Induces Sonic Hedgehog Expression in Pancreatic Cancer Cells via Extracellular Regulated Kinase- and Akt Kinase-mediated Activation of Nuclear Factor κB IMPLICATIONS FOR BIDIRECTIONAL TUMOR-STROMAL INTERACTIONS
Ajay P. Singh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Hyaluronan-CD44v3 Interaction with Oct4-Sox2-Nanog Promotes miR-302 Expression Leading to Self-renewal, Clonal Formation, and Cisplatin Resistance in Cancer Stem Cells from Head and Neck Squamous Cell Carcinoma
Lilly Y. W. Bourguignon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Early events in cell adhesion and polarity during epithelial-mesenchymal transition
Ruby Yun-Ju Huang et al.
JOURNAL OF CELL SCIENCE (2012)
Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells
Toni Celia-Terrassa et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
DNA Damage Repair Pathways in Cancer Stem Cells
Marcello Maugeri-Sacca et al.
MOLECULAR CANCER THERAPEUTICS (2012)
Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors
Austin Gurney et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Monoclonal Antibodies Against Lgr5 Identify Human Colorectal Cancer Stem Cells
Kristel Kemper et al.
STEM CELLS (2012)
Regulation of CD133 by HDAC6 Promotes β-Catenin Signaling to Suppress Cancer Cell Differentiation
Anthony B. Mak et al.
CELL REPORTS (2012)
Regulators of epithelial mesenchymal transition in pancreatic cancer
Shin Hamada et al.
FRONTIERS IN PHYSIOLOGY (2012)
Nestin is a novel target for suppressing pancreatic cancer cell migration, invasion and metastasis
Yoko Matsuda et al.
CANCER BIOLOGY & THERAPY (2011)
Intracellular CD24 Inhibits Cell Invasion by Posttranscriptional Regulation of BART through Interaction with G3BP
Keisuke Taniuchi et al.
CANCER RESEARCH (2011)
DCAMKL-1 Regulates Epithelial-Mesenchymal Transition in Human Pancreatic Cells through a miR-200a-Dependent Mechanism
Sripathi M. Sureban et al.
CANCER RESEARCH (2011)
Nodal/Activin Signaling Drives Self-Renewal and Tumorigenicity of Pancreatic Cancer Stem Cells and Provides a Target for Combined Drug Therapy
Enza Lonardo et al.
CELL STEM CELL (2011)
Epigenetic Modifications Basic Mechanisms and Role in Cardiovascular Disease
Diane E. Handy et al.
CIRCULATION (2011)
Evidence for Partial Epithelial-to-Mesenchymal Transition (pEMT) and Recruitment of Motile Blastoderm Edge Cells During Avian Epiboly
Matt A. Futterman et al.
DEVELOPMENTAL DYNAMICS (2011)
Genistein attenuates WNT signaling by up-regulating sFRP2 in a human colon cancer cell line
Yukun Zhang et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2011)
c-Met Is a Marker of Pancreatic Cancer Stem Cells and Therapeutic Target
Chenwei Li et al.
GASTROENTEROLOGY (2011)
Expression of CD44, CD24 and ESA in pancreatic adenocarcinoma cell lines varies with local microenvironment
Hong-Ji Wei et al.
HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL (2011)
Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium
Francois Gerbe et al.
JOURNAL OF CELL BIOLOGY (2011)
Significance of M2-Polarized Tumor-Associated Macrophage in Pancreatic Cancer
Hiroshi Kurahara et al.
JOURNAL OF SURGICAL RESEARCH (2011)
Sulforaphane Increases Drug-mediated Cytotoxicity Toward Cancer Stem-like Cells of Pancreas and Prostate
Georgios Kallifatidis et al.
MOLECULAR THERAPY (2011)
STEM CELLS Orphan receptors find a home
Walter Birchmeier
NATURE (2011)
Ep-CAM is a significant prognostic factor in pancreatic cancer patients by suppressing cell activity
H. Akita et al.
ONCOGENE (2011)
Differentially Expressed MicroRNAs in Pancreatic Cancer Stem Cells
Dawoon E. Jung et al.
PANCREAS (2011)
Transforming Growth Factor β1 Contributes to the Invasiveness of Pancreatic Ductal Adenocarcinoma Cells Through the Regulation of CD24 Expression
Yoshiki Kitaura et al.
PANCREAS (2011)
Increased Expression of DNA Repair Genes in Invasive Human Pancreatic Cancer Cells
Lesley A. Mathews et al.
PANCREAS (2011)
Hypoxia Induces Tumor Aggressiveness and the Expansion of CD133-Positive Cells in a Hypoxia-Inducible Factor-1 alpha-Dependent Manner in Pancreatic Cancer Cells
Okito Hashimoto et al.
PATHOBIOLOGY (2011)
Resveratrol Inhibits Pancreatic Cancer Stem Cell Characteristics in Human and KrasG12D Transgenic Mice by Inhibiting Pluripotency Maintaining Factors and Epithelial-Mesenchymal Transition
Sharmila Shankar et al.
PLOS ONE (2011)
Expression of Nestin by Neural Cells in the Adult Rat and Human Brain
Michael L. Hendrickson et al.
PLOS ONE (2011)
ALDH Activity Selectively Defines an Enhanced Tumor-Initiating Cell Population Relative to CD133 Expression in Human Pancreatic Adenocarcinoma
Michael P. Kim et al.
PLOS ONE (2011)
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
Michelle C. Mendoza et al.
TRENDS IN BIOCHEMICAL SCIENCES (2011)
Nestin in gastrointestinal and other cancers: Effects on cells and tumor angiogenesis
Toshiyuki Ishiwata et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2011)
Can mesenchymal cells undergo collective cell migration? The case of the neural crest
Eric Theveneau et al.
CELL ADHESION & MIGRATION (2011)
Enhanced Cell Migration and Invasion of CD133+ Pancreatic Cancer Cells Cocultured With Pancreatic Stromal Cells
Taiki Moriyama et al.
CANCER (2010)
EpCAM in carcinogenesis: the good, the bad or the ugly
Bernardina T. F. van der Gun et al.
CARCINOGENESIS (2010)
Bmi-1 Is a Crucial Regulator of Prostate Stem Cell Self-Renewal and Malignant Transformation
Rita U. Lukacs et al.
CELL STEM CELL (2010)
Characterization of CD24 expression in intraductal papillary mucinous neoplasms and ductal carcinoma of the pancreas
Naoki Ikenaga et al.
HUMAN PATHOLOGY (2010)
Inhibition of Notch Signaling in Glioblastoma Targets Cancer Stem Cells via an Endothelial Cell Intermediate
Koos E. Hovinga et al.
STEM CELLS (2010)
Review: Targeting the Hedgehog pathway in cancer
Sachin Gupta et al.
Therapeutic Advances in Medical Oncology (2010)
Role of Chemokine Network in the Development and Progression of Ovarian Cancer: A Potential Novel Pharmacological Target
Federica Barbieri et al.
JOURNAL OF ONCOLOGY (2010)
Low-Level Expression of MicroRNAs let-7d and miR-205 Are Prognostic Markers of Head and Neck Squamous Cell Carcinoma
Geoffrey Childs et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Aldehyde dehydrogenase 1 is a putative marker for cancer stem cells in head and neck squamous cancer
Yu-Chih Chen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
High expression of CXCR4 may predict poor survival in resected pancreatic adenocarcinoma
R. Marechal et al.
BRITISH JOURNAL OF CANCER (2009)
Acquisition of Epithelial-Mesenchymal Transition Phenotype of Gemcitabine-Resistant Pancreatic Cancer Cells Is Linked with Activation of the Notch Signaling Pathway
Zhiwei Wang et al.
CANCER RESEARCH (2009)
Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer
Thiruvengadam Arumugam et al.
CANCER RESEARCH (2009)
Characterization and functional analysis of a slow cycling stem cell-like subpopulation in pancreas adenocarcinoma
Jennifer L. Dembinski et al.
CLINICAL & EXPERIMENTAL METASTASIS (2009)
Prominin-1/CD133 Marks Stem Cells and Early Progenitors in Mouse Small Intestine
Hugo J. Snippert et al.
GASTROENTEROLOGY (2009)
CD44-positive cells are responsible for gemcitabine resistance in pancreatic cancer cells
Sung Pil Hong et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
Association of reactive oxygen species levels and radioresistance in cancer stem cells
Maximilian Diehn et al.
NATURE (2009)
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
Ulrich Wellner et al.
NATURE CELL BIOLOGY (2009)
MicroRNA miR-34 Inhibits Human Pancreatic Cancer Tumor-Initiating Cells
Qing Ji et al.
PLOS ONE (2009)
Cancer-Stellate Cell Interactions Perpetuate the Hypoxia-Fibrosis Cycle in Pancreatic Ductal Adenocarcinoma
Mert M. Erkan et al.
NEOPLASIA (2009)
CD133 expression is correlated with lymph node metastasis and vascular endothelial growth factor-C expression in pancreatic cancer
S. Maeda et al.
BRITISH JOURNAL OF CANCER (2008)
The epithelial-mesenchymal transition generates cells with properties of stem cells
Sendurai A. Mani et al.
CELL (2008)
A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
Ulrike Burk et al.
EMBO REPORTS (2008)
Pancreatic cancer stem cells
Cheong J. Lee et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
Cutaneous cancer stem cell maintenance is dependent on β-catenin signalling
Ilaria Malanchi et al.
NATURE (2008)
The mir-200 family and mir-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
Philip A. Gregory et al.
NATURE CELL BIOLOGY (2008)
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
Ittai Ben-Porath et al.
NATURE GENETICS (2008)
Ep-CAM expression in pancreatic and ampullary carcinomas: frequency and prognostic relevance
D. Fong et al.
JOURNAL OF CLINICAL PATHOLOGY (2008)
Hypoxia up-regulates hypoxia-inducible factor-1α transcription by involving phosphatidylinositol 3-kinase and nuclear factor κB in pulmonary artery smooth muscle cells
Rachida S. BelAiba et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Snail1a and Snail1b cooperate in the anterior migration of the axial mesendoderm in the zebrafish embryo
Maria J. Blanco et al.
DEVELOPMENT (2007)
Identification of stem cells in small intestine and colon by marker gene Lgr5
Nick Barker et al.
NATURE (2007)
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
Patrick C. Hermann et al.
CELL STEM CELL (2007)
Immunohistochemical analysis of nestin and c-kit and their significance in pancreatic tumors
Nobuyuki Ohike et al.
PATHOLOGY INTERNATIONAL (2007)
Nestin expression in the kidney with an obstructed ureter
T. Sakairi et al.
KIDNEY INTERNATIONAL (2007)
Isolation of mouse pancreatic ductal progenitor cells expressing CD133 and c-Met by flow cytornetric cell sorting
Yuji Oshima et al.
GASTROENTEROLOGY (2007)
Identification of pancreatic cancer stem cells
Chenwei Li et al.
CANCER RESEARCH (2007)
MicroRNA-cancer connection: The beginning of a new tale
George Adrian Calin et al.
CANCER RESEARCH (2006)
GLI transcription factors: Mediators of oncogenic Hedgehog signalling
M Kasper et al.
EUROPEAN JOURNAL OF CANCER (2006)
CD24 expression causes the acquisition of multiple cellular properties associated with tumor growth and metastasis
P Baumann et al.
CANCER RESEARCH (2005)
Opinion - Migrating cancer stem cells - an integrated concept of malignant tumour progression
T Brabletz et al.
NATURE REVIEWS CANCER (2005)
Transcriptional regulatory networks in lipid metabolism control ABCA1 expression
G Schmitz et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2005)
Loss of Ep-CAM (CO17-1A) expression predicts survival in patients with gastric cancer
I Songun et al.
BRITISH JOURNAL OF CANCER (2005)
The carcinoma-associated antigen EpCAM upregulates c-myc and induces cell proliferation
M Münz et al.
ONCOGENE (2004)
Frequent EpCam protein expression in human carcinomas
PT Went et al.
HUMAN PATHOLOGY (2004)
Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions
K Ohuchida et al.
CANCER RESEARCH (2004)
Capillary electrophoretic determination of theanine, caffeine, and catechins in fresh tea leaves and oolong tea and their effects on rat neurosphere adhesion and migration
CN Chen et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2003)
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
SP Thayer et al.
NATURE (2003)
A role for Wnt signalling in self-renewal of haematopoietic stem cells
T Reya et al.
NATURE (2003)
The epithelial cell adhesion molecule (Ep-CAM) as a morphoregulatory molecule is a tool in surgical pathology
MJ Winter et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
Epithelial-mesenchymal transitions in tumour progression
JP Thiery
NATURE REVIEWS CANCER (2002)
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T Reya et al.
NATURE (2001)
Ep-CAM overexpression in breast cancer as a predictor of survival
G Gastl et al.
LANCET (2000)
The transcription factor Snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
A Cano et al.
NATURE CELL BIOLOGY (2000)