4.7 Article

Novel ARHGAP23-FER fusion in a metastatic spindle cell-predominant neoplasm with a myofibroblastic phenotype and a sustained metabolic response to lorlatinib

Journal

CANCER
Volume 127, Issue 22, Pages 4124-4130

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WILEY
DOI: 10.1002/cncr.33854

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A novel ARHGAP23-FER fusion was identified in a metastatic spindle-cell soft-tissue neoplasm, which exhibited a rapid and sustained metabolic response to the tyrosine kinase inhibitor lorlatinib.
A metastatic spindle-cell soft-tissue neoplasm was found to carry a novel ARHGAP23-FER fusion. The tumor showed a rapid and sustained metabolic response to tyrosine kinase inhibitor lorlatinib.

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