Journal
BIOSENSORS & BIOELECTRONICS
Volume 182, Issue -, Pages -Publisher
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2021.113193
Keywords
Exhaled breath condensate; Biomarkers; Biosensors; Chemical sensors
Categories
Funding
- UEFISCDI [PN-III-P2-2.1-PED-2019-2746, 266PED]
- National Institutes of Health [R01 DK094932]
- Innovation Discretionary Fund (DFI) Award through the MSU Office of the Senior Vice President for Research and Innovation
- MSU Department of Medicine SEED Grant [GS100060-C5BHS]
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This mini-review introduces the reader to research on exhaled breath analysis for detecting abnormal chemical markers reflective of respiratory diseases. It discusses two main groups of sensing methods: mass spectrometry and (bio)sensors, with a focus on biosensor applications for EB and EBC analyses. The review concludes with recommendations for future development of EBC biomarker sensing in the near and long term.
This goal of this minireview is to introduce the reader to the area of research concerned with exhaled breath analysis for the purpose of detecting abnormal levels of physiologically-relevant chemical markers reflective of respiratory diseases. Two main two groups of sensing methods are reviewed: mass spectrometry and (bio)sensors. The discussion focuses on biosensor applications for EB and EBC analyses, which are presented in detail. The review finishes with conclusions and future perspectives, including recommendations for future near-term and long-term development of EBC biomarker sensing.
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