Related references
Note: Only part of the references are listed.Neurobiology of ARID1B haploinsufficiency related to neurodevelopmental and psychiatric disorders
Jeffrey J. Moffat et al.
MOLECULAR PSYCHIATRY (2022)
Mechanisms of synaptic transmission dysregulation in the prefrontal cortex: pathophysiological implications
Zhen Yan et al.
MOLECULAR PSYCHIATRY (2022)
Consequences of NMDA receptor deficiency can be rescued in the adult brain
Catharine A. Mielnik et al.
MOLECULAR PSYCHIATRY (2021)
Long-term maturation of human cortical organoids matches key early postnatal transitions
Aaron Gordon et al.
NATURE NEUROSCIENCE (2021)
The molecular biology of FMRP: new insights into fragile X syndrome
Joel D. Richter et al.
NATURE REVIEWS NEUROSCIENCE (2021)
Antisense oligonucleotide therapy in a humanized mouse model of MECP2 duplication syndrome
Yingyao Shao et al.
SCIENCE TRANSLATIONAL MEDICINE (2021)
Synergistic inhibition of histone modifiers produces therapeutic effects in adult Shank3-deficient mice
Freddy Zhang et al.
TRANSLATIONAL PSYCHIATRY (2021)
Oxytocin, Neural Plasticity, and Social Behavior
Robert C. Froemke et al.
Annual Review of Neuroscience (2021)
PKC epsilon as a neonatal target to correct FXS-linked AMPA receptor translocation in the hippocampus, boost PVN oxytocin expression, and normalize adult behavior in Fmr1 knockout mice
Alexandra Marsillo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2021)
Engineered microRNA-based regulatory element permits safe high-dose miniMECP2 gene therapy in Rett mice
Sarah E. Sinnett et al.
BRAIN (2021)
Reciprocal control of translation and transcription in autism spectrum disorder
Francesco Longo et al.
EMBO REPORTS (2021)
The role of GABAergic signalling in neurodevelopmental disorders
Xin Tang et al.
NATURE REVIEWS NEUROSCIENCE (2021)
Tanc2-mediated mTOR inhibition balances mTORC1/2 signaling in the developing mouse brain and human neurons
Sun-Gyun Kim et al.
NATURE COMMUNICATIONS (2021)
Twenty Years of SynGAP Research: From Synapses to Cognition
Timothy R. Gamache et al.
JOURNAL OF NEUROSCIENCE (2020)
Awake functional MRI detects neural circuit dysfunction in a mouse model of autism
Tomokazu Tsurugizawa et al.
SCIENCE ADVANCES (2020)
CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors
Dan Wang et al.
CELL (2020)
Reactivation of FMR1 gene expression is a promising strategy for fragile X syndrome therapy
Ekaterina M. Shitik et al.
GENE THERAPY (2020)
Early correction of synaptic long-term depression improves abnormal anxiety-like behavior in adult GluN2B-C456Y-mutant mice
Wangyong Shin et al.
PLOS BIOLOGY (2020)
Early Restoration of Shank3 Expression in Shank3 Knock-Out Mice Prevents Core ASD-Like Behavioral Phenotypes
Thomas C. Jaramillo et al.
eNeuro (2020)
Advances in understanding of Rett syndrome and MECP2 duplication syndrome: prospects for future therapies
Alexander J. Sandweiss et al.
LANCET NEUROLOGY (2020)
Regulation of autism-relevant behaviors by cerebellar-prefrontal cortical circuits
Elyza Kelly et al.
NATURE NEUROSCIENCE (2020)
Critical period regulation across multiple timescales
Rebecca K. Reh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Neurodevelopmental Disorders: From Genetics to Functional Pathways
Ilaria Parenti et al.
TRENDS IN NEUROSCIENCES (2020)
Opportunities and limitations of genetically modified nonhuman primate models for neuroscience research
Guoping Feng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Looking at neurodevelopment through a big data lens
James Briscoe et al.
SCIENCE (2020)
Molecular mechanisms for targeted ASD treatments
Bernadette Basilico et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2020)
Critical period inhibition of NKCC1 rectifies synapse plasticity in the somatosensory cortex and restores adult tactile response maps in fragile X mice
Qionger He et al.
MOLECULAR PSYCHIATRY (2019)
Environmental enrichment, new neurons and the neurobiology of individuality
Gerd Kempermann
NATURE REVIEWS NEUROSCIENCE (2019)
A Synaptic Perspective of Fragile X Syndrome and Autism Spectrum Disorders
Claudia Bagni et al.
NEURON (2019)
Excitation-inhibition balance as a framework for investigating mechanisms in neuropsychiatric disorders
Vikaas S. Sohal et al.
MOLECULAR PSYCHIATRY (2019)
Single-cell genomics identifies cell type-specific molecular changes in autism
Dmitry Velmeshev et al.
SCIENCE (2019)
Sustained correction of associative learning deficits after brief, early treatment in a rat model of Fragile X Syndrome
Antonis Asiminas et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
Re-expression of SynGAP protein in adulthood improves translatable measures of brain function and behavior
Thomas K. Creson et al.
ELIFE (2019)
Pharmacological enhancement of KCC2 gene expression exerts therapeutic effects on human Rett syndrome neurons and Mecp2 mutant mice
Xin Tang et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
Disruptive mutations in TANC2 define a neurodevelopmental syndrome associated with psychiatric disorders
Hui Guo et al.
NATURE COMMUNICATIONS (2019)
Abnormal Striatal Development Underlies the Early Onset of Behavioral Deficits in Shank3B-/- Mice
Rui Tiago Peixoto et al.
CELL REPORTS (2019)
Early Correction of N-Methyl-D-Aspartate Receptor Function Improves Autistic-like Social Behaviors in Adult Shank2-/- Mice
Changuk Chung et al.
BIOLOGICAL PSYCHIATRY (2019)
The distinct methylation landscape of maturing neurons and its role in Rett syndrome pathogenesis
Laura A. Lavery et al.
CURRENT OPINION IN NEUROBIOLOGY (2019)
Discovering translational biomarkers in neurodevelopmental disorders
Mustafa Sahin et al.
NATURE REVIEWS DRUG DISCOVERY (2019)
Increased Excitation-Inhibition Ratio Stabilizes Synapse and Circuit Excitability in Four Autism Mouse Models
Michelle W. Antoine et al.
NEURON (2019)
Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome
Elizabeth M. Berry-Kravis et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Viral Strategies for Targeting the Central and Peripheral Nervous Systems
Claire N. Bedbrook et al.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 41 (2018)
Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene
X. Shawn Liu et al.
CELL (2018)
Disrupted circuits in mouse models of autism spectrum disorder and intellectual disability
Carla E. M. Golden et al.
CURRENT OPINION IN NEUROBIOLOGY (2018)
Abnormal mTOR Activation in Autism
Kellen D. Winden et al.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 41 (2018)
Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition
Luye Qin et al.
NATURE NEUROSCIENCE (2018)
Nanoparticle delivery of CRISPR into the brain rescues a mouse model of fragile X syndrome from exaggerated repetitive behaviours
Bumwhee Lee et al.
NATURE BIOMEDICAL ENGINEERING (2018)
The mouse as a model for neuropsychiatric drug development
James R. Howe et al.
CURRENT BIOLOGY (2018)
5-HT release in nucleus accumbens rescues social deficits in mouse autism model
Jessica J. Walsh et al.
NATURE (2018)
Sensitive Periods for Cerebellar-Mediated Autistic-like Behaviors
Peter T. Tsai et al.
CELL REPORTS (2018)
Metformin Administration During Early Postnatal Life Rescues Autistic-Like Behaviors in the BTBR T+Itpr3tf/J Mouse Model of Autism
Lian Wang et al.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2018)
De novo mutations and rare variants occurring in NMDA receptors
Wenshu XiangWei et al.
CURRENT OPINION IN PHYSIOLOGY (2018)
Clinical and biological progress over 50 years in Rett syndrome
Helen Leonard et al.
NATURE REVIEWS NEUROLOGY (2017)
The Role of the Immune System in Autism Spectrum Disorder
Amory Meltzer et al.
NEUROPSYCHOPHARMACOLOGY (2017)
Reversing behavioural abnormalities in mice exposed to maternal inflammation
Yeong Shin Yim et al.
NATURE (2017)
Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring
Sangdoo Kim et al.
NATURE (2017)
Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and developmental-disability biases
Holly A. F. Stessman et al.
NATURE GENETICS (2017)
Metformin ameliorates core deficits in a mouse model of fragile X syndrome
Ilse Gantois et al.
NATURE MEDICINE (2017)
Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior
Eui-Man Jung et al.
NATURE NEUROSCIENCE (2017)
SHANK proteins: roles at the synapse and in autism spectrum disorder
Patricia Monteiro et al.
NATURE REVIEWS NEUROSCIENCE (2017)
The BRAIN Initiative Cell Census Consortium: Lessons Learned toward Generating a Comprehensive Brain Cell Atlas
Joseph R. Ecker et al.
NEURON (2017)
Is functional brain connectivity atypical in autism? A systematic review of EEG and MEG studies
Christian O'Reilly et al.
PLOS ONE (2017)
Modulation of prefrontal cortex excitation/inhibition balance rescues social behavior in CNTNAP2-deficient mice
Aslihan Selimbeyoglu et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Vitamin D treatment during pregnancy prevents autism-related phenotypes in a mouse model of maternal immune activation
Stephanie Vuillermot et al.
MOLECULAR AUTISM (2017)
Environmental risk factors for autism: an evidence-based review of systematic reviews and meta-analyses
Amirhossein Modabbernia et al.
MOLECULAR AUTISM (2017)
Fragile X syndrome
Randi J. Hagerman et al.
NATURE REVIEWS DISEASE PRIMERS (2017)
Serotonin rebalances cortical tuning and behavior linked to autism symptoms in 15q11-13 CNV mice
Nobuhiro Nakai et al.
SCIENCE ADVANCES (2017)
Synaptic Neurexin Complexes: A Molecular Code for the Logic of Neural Circuits
Thomas C. Sudhof
CELL (2017)
Excitation/Inhibition Imbalance in Animal Models of Autism Spectrum Disorders
Eunee Lee et al.
BIOLOGICAL PSYCHIATRY (2017)
Maternal Immune Activation and Autism Spectrum Disorder: From Rodents to Nonhuman and Human Primates
Milo Careaga et al.
BIOLOGICAL PSYCHIATRY (2017)
Adult restoration of Shank3 expression rescues selective autistic-like phenotypes
Yuan Mei et al.
NATURE (2016)
CHD8 haploinsufficiency results in autistic-like phenotypes in mice
Yuta Katayama et al.
NATURE (2016)
Developmental timing and critical windows for the treatment of psychiatric disorders
Oscar Marin
NATURE MEDICINE (2016)
Early hyperactivity and precocious maturation of corticostriatal circuits in Shank3B-/- mice
Rui T. Peixoto et al.
NATURE NEUROSCIENCE (2016)
SHANK3 controls maturation of social reward circuits in the VTA
Sebastiano Bariselli et al.
NATURE NEUROSCIENCE (2016)
MONOGENIC MOUSE MODELS OF AUTISM SPECTRUM DISORDERS: COMMON MECHANISMS AND MISSING LINKS
S. W. Hulbert et al.
NEUROSCIENCE (2016)
Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons
Fei Yi et al.
SCIENCE (2016)
The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
Gloria B. Choi et al.
SCIENCE (2016)
Clinical trials for neurodevelopmental disorders: At a therapeutic frontier
Shafali S. Jeste et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Syngap1 Haploinsufficiency Damages a Postnatal Critical Period of Pyramidal Cell Structural Maturation Linked to Cortical Circuit Assembly
Massimiliano Aceti et al.
BIOLOGICAL PSYCHIATRY (2015)
Genetic Epidemiology and Insights into Interactive Genetic and Environmental Effects in Autism Spectrum Disorders
Young Shin Kim et al.
BIOLOGICAL PSYCHIATRY (2015)
NMDA receptor dysfunction in autism spectrum disorders
Eun-Jae Lee et al.
CURRENT OPINION IN PHARMACOLOGY (2015)
Shank synaptic scaffold proteins: keys to understanding the pathogenesis of autism and other synaptic disorders
Carlo Sala et al.
JOURNAL OF NEUROCHEMISTRY (2015)
Neurological and neuropsychiatric aspects of tuberous sclerosis complex
Paolo Curatolo et al.
LANCET NEUROLOGY (2015)
Reversal of phenotypes in MECP2 duplication mice using genetic rescue or antisense oligonucleotides
Yehezkel Sztainberg et al.
NATURE (2015)
Therapeutic genome editing: prospects and challenges
David Benjamin Turitz Cox et al.
NATURE MEDICINE (2015)
From the genetic architecture to synaptic plasticity in autism spectrum disorder
Thomas Bourgeron
NATURE REVIEWS NEUROSCIENCE (2015)
Excitatory/Inhibitory Balance and Circuit Homeostasis in Autism Spectrum Disorders
Sacha B. Nelson et al.
NEURON (2015)
Genes, circuits, and precision therapies for autism and related neurodevelopmental disorders
Mustafa Sahin et al.
SCIENCE (2015)
Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism
Olga Penagarikano et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Neuromodulation of excitatory synaptogenesis in striatal development
Yevgenia Kozorovitskiy et al.
eLife (2015)
Mutations and Modeling of the Chromatin Remodeler CHD8 Define an Emerging Autism Etiology
Rebecca A. Barnard et al.
FRONTIERS IN NEUROSCIENCE (2015)
Early Social Enrichment Rescues Adult Behavioral and Brain Abnormalities in a Mouse Model of Fragile X Syndrome
Diego Oddi et al.
NEUROPSYCHOPHARMACOLOGY (2015)
Rescue of behavioral and EEG deficits in male and female Mecp2-deficient mice by delayed Mecp2 gene reactivation
Min Lang et al.
HUMAN MOLECULAR GENETICS (2014)
The Developmental Switch in GABA Polarity Is Delayed in Fragile X Mice
Qionger He et al.
JOURNAL OF NEUROSCIENCE (2014)
Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality
Tzyy-Nan Huang et al.
NATURE NEUROSCIENCE (2014)
Oxytocin-Mediated GABA Inhibition During Delivery Attenuates Autism Pathogenesis in Rodent Offspring
Roman Tyzio et al.
SCIENCE (2014)
Transcriptional and functional complexity of Shank3 provides a molecular framework to understand the phenotypic heterogeneity of SHANK3 causing autism and Shank3 mutant mice
Xiaoming Wang et al.
MOLECULAR AUTISM (2014)
Gene x environment interactions in autism spectrum disorders: role of epigenetic mechanisms
Sylvie Tordjman et al.
FRONTIERS IN PSYCHIATRY (2014)
SYNGAP1 Links the Maturation Rate of Excitatory Synapses to the Duration of Critical-Period Synaptic Plasticity
James P. Clement et al.
JOURNAL OF NEUROSCIENCE (2013)
Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin
Guel Doelen et al.
NATURE (2013)
Activity-dependent neuronal signalling and autism spectrum disorder
Daniel H. Ebert et al.
NATURE (2013)
mTOR complexes in neurodevelopmental and neuropsychiatric disorders
Mauro Costa-Mattioli et al.
NATURE NEUROSCIENCE (2013)
Modeling Autism by SHANK Gene Mutations in Mice
Yong-hui Jiang et al.
NEURON (2013)
Morphological and functional reversal of phenotypes in a mouse model of Rett syndrome
Lianne Robinson et al.
BRAIN (2012)
Pathogenic SYNGAP1 Mutations Impair Cognitive Development by Disrupting Maturation of Dendritic Spine Synapses
James P. Clement et al.
CELL (2012)
Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function
Hyejung Won et al.
NATURE (2012)
Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice
Peter T. Tsai et al.
NATURE (2012)
Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome
Rodney C. Samaco et al.
NATURE GENETICS (2012)
Serotonin in the Modulation of Neural Plasticity and Networks: Implications for Neurodevelopmental Disorders
Klaus-Peter Lesch et al.
NEURON (2012)
Shared Synaptic Pathophysiology in Syndromic and Nonsyndromic Rodent Models of Autism
Stephane J. Baudouin et al.
SCIENCE (2012)
The Role of MeCP2 in the Brain
Jacky Guy et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
Neocortical excitation/inhibition balance in information processing and social dysfunction
Ofer Yizhar et al.
NATURE (2011)
Shank3 mutant mice display autistic-like behaviours and striatal dysfunction
Joao Peca et al.
NATURE (2011)
In utero exposure to cocaine delays postnatal synaptic maturation of glutamatergic transmission in the VTA
Camilla Bellone et al.
NATURE NEUROSCIENCE (2011)
Adult Neural Function Requires MeCP2
Christopher M. McGraw et al.
SCIENCE (2011)
The Postsynaptic Organization of Synapses
Morgan Sheng et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)
Regulation of Dendritic Spines, Spatial Memory, and Embryonic Development by the TANC Family of PSD-95-Interacting Proteins
Seungnam Han et al.
JOURNAL OF NEUROSCIENCE (2010)
Critical Period Plasticity Is Disrupted in the Barrel Cortex of Fmr1 Knockout Mice
Emily G. Harlow et al.
NEURON (2010)
Decreased Exploratory Activity in a Mouse Model of 15q Duplication Syndrome; Implications for Disturbance of Serotonin Signaling
Kota Tamada et al.
PLOS ONE (2010)
mTOR signaling: At the crossroads of plasticity, memory and disease
Charles A. Hoeffer et al.
TRENDS IN NEUROSCIENCES (2010)
Abnormal Behavior in a Chromosome-Engineered Mouse Model for Human 15q11-13 Duplication Seen in Autism
Jin Nakatani et al.
CELL (2009)
Circuit and plasticity defects in the developing somatosensory cortex of Fmr1 knock-out mice
Ingrid Bureau et al.
JOURNAL OF NEUROSCIENCE (2008)
Neuroligins and neurexins link synaptic function to cognitive disease
Thomas C. Sudhof
NATURE (2008)
Early behavioral intervention, brain plasticity, and the prevention of autism spectrum disorder
Geraldine Dawson
DEVELOPMENT AND PSYCHOPATHOLOGY (2008)
GABA: A pioneer transmitter that excites immature neurons and generates primitive oscillations
Yehezkel Ben-Ari et al.
PHYSIOLOGICAL REVIEWS (2007)
Reversal of neurological defects in a mouse model of Rett syndrome
Jacky Guy et al.
SCIENCE (2007)
Maternal oxytocin triggers a transient inhibitory switch in GABA signaling in the fetal brain during delivery
Roman Tyzio et al.
SCIENCE (2006)
Searching for ways out of the autism maze: genetic, epigenetic and environmental clues
Antonio M. Persico et al.
TRENDS IN NEUROSCIENCES (2006)
Environmental enrichment reverses behavioral alterations in rats prenatally exposed to valproic acid: Issues for a therapeutic approach in autism
T Schneider et al.
NEUROPSYCHOPHARMACOLOGY (2006)
Mild overexpression of MeCP2 causes a progressive neurological disorder in mice
AL Collins et al.
HUMAN MOLECULAR GENETICS (2004)
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
J Guy et al.
NATURE GENETICS (2001)
Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
RZ Chen et al.
NATURE GENETICS (2001)
Share Paper
