Related references
Note: Only part of the references are listed.Targeting hypoxia in the tumor microenvironment: a potential strategy to improve cancer immunotherapy
Bin Wang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2021)
Selective autophagy of intracellular organelles: recent research advances
Wen Li et al.
THERANOSTICS (2021)
Tumor Immunology and Tumor Evolution: Intertwined Histories
Jerome Galon et al.
IMMUNITY (2020)
The significance of exosomes in the development and treatment of hepatocellular carcinoma
Xin Li et al.
MOLECULAR CANCER (2020)
Plasma-activated medium promotes autophagic cell death along with alteration of the mTOR pathway
Nobuhisa Yoshikawa et al.
SCIENTIFIC REPORTS (2020)
Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation
Leena P. Bharath et al.
CELL METABOLISM (2020)
A Randomized Phase II Preoperative Study of Autophagy Inhibition with High-Dose Hydroxychloroquine and Gemcitabine/Nab-Paclitaxel in Pancreatic Cancer Patients
Herbert J. Zeh et al.
CLINICAL CANCER RESEARCH (2020)
Autophagy promotes mammalian survival by suppressing oxidative stress and p53
Yang Yang et al.
GENES & DEVELOPMENT (2020)
ULK1 inhibition as a targeted therapeutic strategy for FLT3-ITD-mutated acute myeloid leukemia
Doh Yu Hwang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020)
Relevance of immune cell and tumor microenvironment imaging in the new era of immunotherapy
Filippo Galli et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020)
Multi-site-mediated entwining of the linear WIR-motif around WIPI β-propellers for autophagy
Jinqi Ren et al.
NATURE COMMUNICATIONS (2020)
mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges
Zhilin Zou et al.
CELL AND BIOSCIENCE (2020)
Therapeutic Targeting of Autophagy for Renal Cell Carcinoma Therapy
Trace M. Jones et al.
CANCERS (2020)
Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I
Keisuke Yamamoto et al.
NATURE (2020)
Molecular Insights Into Therapeutic Potential of Autophagy Modulation by Natural Products for Cancer Stem Cells
Md. Ataur Rahman et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
Notch Transduction in Non-Small Cell Lung Cancer
Amnah Sharif et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Dual targeting of NUAK1 and ULK1 using the multitargeted inhibitor MRT68921 exerts potent antitumor activities
Yiran Chen et al.
CELL DEATH & DISEASE (2020)
mTOR-mediated cancer drug resistance suppresses autophagy and generates a druggable metabolic vulnerability
Niklas Gremke et al.
NATURE COMMUNICATIONS (2020)
Antileukemic activity of the VPS34-IN1 inhibitor in acute myeloid leukemia
Godelieve Meunier et al.
ONCOGENESIS (2020)
Cep55 overexpression promotes genomic instability and tumorigenesis in mice
Debottam Sinha et al.
COMMUNICATIONS BIOLOGY (2020)
Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response
Laura Poillet-Perez et al.
NATURE CANCER (2020)
Lys05-A Promising Autophagy Inhibitor in the Radiosensitization Battle: Phosphoproteomic Perspective
Martin Ondrej et al.
CANCER GENOMICS & PROTEOMICS (2020)
Ovatodiolide suppresses nasopharyngeal cancer by targeting stem cell-like population, inducing apoptosis, inhibiting EMT and dysregulating JAK/STAT signaling pathway
Shao-Cheng Liu et al.
PHYTOMEDICINE (2019)
Autophagy inhibition specifically promotes epithelial-mesenchymal transition and invasion in RAS-mutated cancer cells
Yihua Wang et al.
AUTOPHAGY (2019)
Autophagy protein ATG5 regulates CD36 expression and anti-tumor MHC class II antigen presentation in dendritic cells
Dong Sun Oh et al.
AUTOPHAGY (2019)
Autophagy and cancer stem cells: molecular mechanisms and therapeutic applications
Francesca Nazio et al.
CELL DEATH AND DIFFERENTIATION (2019)
The relationship between autophagy and the immune system and its applications for tumor immunotherapy
Guan-Min Jiang et al.
MOLECULAR CANCER (2019)
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer
Kirsten L. Bryant et al.
NATURE MEDICINE (2019)
Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers
Conan G. Kinsey et al.
NATURE MEDICINE (2019)
Cathelicidin Suppresses Colon Cancer Metastasis via a P2RX7-Dependent Mechanism
Jiani Wang et al.
MOLECULAR THERAPY-ONCOLYTICS (2019)
Control of the Epithelial-to-Mesenchymal Transition and Cancer Metastasis by Autophagy-Dependent SNAI1 Degradation
Sahib Zada et al.
CELLS (2019)
FOXO3 directly regulates an autophagy network to functionally regulate proteostasis in adult neural stem cells
Amanda J. Audesse et al.
PLOS GENETICS (2019)
In Situ Manipulation of Dendritic Cells by an Autophagy-Regulative Nanoactivator Enables Effective Cancer Immunotherapy
Yi Wang et al.
ACS NANO (2019)
Autophagy manipulation as a strategy for efficient anticancer therapies: possible consequences
Mara Cirone et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
Targeting Autophagy in Cancer: Recent Advances and Future Directions
Ravi K. Amaravadi et al.
CANCER DISCOVERY (2019)
Hydroxychloroquine potentiates the anti-cancer effect of bevacizumab on glioblastoma via the inhibition of autophagy
Lin-qing Liu et al.
BIOMEDICINE & PHARMACOTHERAPY (2019)
A Potent Autophagy Inhibitor (Lys05) Enhances the Impact of Ionizing Radiation on Human Lung Cancer Cells H1299
Lucie Cechakova et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Resveratrol As A Natural Regulator Of Autophagy For Prevention And Treatment Of Cancer
Yuanyuan Tian et al.
ONCOTARGETS AND THERAPY (2019)
Biological Functions of Autophagy Genes: A Disease Perspective
Beth Levine et al.
CELL (2019)
Autophagy in cancer: moving from understanding mechanism to improving therapy responses in patients
Jean M. Mulcahy Levy et al.
CELL DEATH AND DIFFERENTIATION (2019)
Autophagosome maturation: An epic journey from the ER to lysosomes
Yan G. Zhao et al.
JOURNAL OF CELL BIOLOGY (2019)
Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the PI-PLCε-NF-B signaling pathway and VEGF-C/ Bcl-2 expression
Yunzhao Chen et al.
MOLECULAR CANCER (2019)
Targeting surface nucleolin induces autophagy-dependent cell death in pancreatic cancer via AMPK activation
Cheng Xu et al.
ONCOGENE (2019)
PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer
Vito W. Rebecca et al.
CANCER DISCOVERY (2019)
Metformin prevents cell tumorigenesis through autophagy- related cell death
Mauro De Santi et al.
SCIENTIFIC REPORTS (2019)
Neferine induces autophagy-dependent cell death in apoptosis-resistant cancers via ryanodine receptor and Ca2+-dependent mechanism
Betty Yuen Kwan Law et al.
SCIENTIFIC REPORTS (2019)
Plasma-activated medium triggers cell death and the presentation of immune activating danger signals in melanoma and pancreatic cancer cells
Amalie Azzariti et al.
SCIENTIFIC REPORTS (2019)
Targeting autophagy blocks melanoma growth by bringing natural killer cells to the tumor battlefield
Muhammad Zaeem Noman et al.
AUTOPHAGY (2018)
Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion
Mario Mauthe et al.
AUTOPHAGY (2018)
Pro-survival autophagy and cancer cell resistance to therapy
Chandan Kanta Das et al.
CANCER AND METASTASIS REVIEWS (2018)
Docetaxel-mediated autophagy promotes chemoresistance in castration-resistant prostate cancer cells by inhibiting STAT3
Fei Hu et al.
CANCER LETTERS (2018)
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
Lorenzo Galluzzi et al.
CELL DEATH AND DIFFERENTIATION (2018)
Autophagy Inhibition Mediates Apoptosis Sensitization in Cancer Therapy by Relieving FOXO3a Turnover
Brent E. Fitzwalter et al.
DEVELOPMENTAL CELL (2018)
Uncoupling effects of estrogen receptor on LKB1/AMPK interaction upon adiponectin exposure in breast cancer
Loredana Mauro et al.
FASEB JOURNAL (2018)
Matrine inhibiting pancreatic cells epithelial-mesenchymal transition and invasion through ROS/NF-κB/MMPs pathway
Minna Huang et al.
LIFE SCIENCES (2018)
The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168
Xiaoduo Xie et al.
NATURE CELL BIOLOGY (2018)
The coming of age of chaperone-mediated autophagy
Susmita Kaushik et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
Mechanism and medical implications of mammalian autophagy
Ivan Dikic et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells
Sarmistha Talukdar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and nonautonomous Mechanisms
Annan Yang et al.
CANCER DISCOVERY (2018)
Resveratrol ameliorates autophagic flux to promote functional recovery in rats after spinal cord injury
Peng Wang et al.
Oncotarget (2018)
Targeting Autophagy in the Tumor Microenvironment: New Challenges and Opportunities for Regulating Tumor Immunity
Bassam Janji et al.
FRONTIERS IN IMMUNOLOGY (2018)
Yap promotes hepatocellular carcinoma metastasis and mobilization via governing cofilin/F-actin/lamellipodium axis by regulation of JNK/Bnip3/SERCA/CaMKII pathways
Chen Shi et al.
REDOX BIOLOGY (2018)
Migration inhibition of water stress proteins from Nostoc commune Vauch. via activation of autophagy in DLD-1 cells
Songjia Guo et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)
Macroautophagy Regulates Nuclear NOTCH1 Activity Through Multiple p62 Binding Sites
Ting Zhang et al.
IUBMB LIFE (2018)
Autophagy induces transforming growth factor-β-dependent epithelial-mesenchymal transition in hepatocarcinoma cells through cAMP response element binding signalling
Shaobo Hu et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2018)
Autophagy orchestrates the regulatory program of tumor-associated myeloid-derived suppressor cells
Themis Alissafi et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Targeted Inhibition of ULK1 Promotes Apoptosis and Suppresses Tumor Growth and Metastasis in Neuroblastoma
Christopher M. Dower et al.
MOLECULAR CANCER THERAPEUTICS (2018)
Hyperphosphatemia Promotes Senescence of Myoblasts by Impairing Autophagy Through Ilk Overexpression, A Possible Mechanism Involved in Sarcopenia
Patricia Sosa et al.
AGING AND DISEASE (2018)
Overexpression of ULK1 Represents a Potential Diagnostic Marker for Clear Cell Renal Carcinoma and the Antitumor Effects of SBI-0206965
Jun Lu et al.
EBIOMEDICINE (2018)
Autophagy maintains tumour growth through circulating arginine
Laura Poillet-Perez et al.
NATURE (2018)
mTOR signalling and cellular metabolism are mutual determinants in cancer
Dirk Mossmann et al.
NATURE REVIEWS CANCER (2018)
A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress
Katie R. Martin et al.
ISCIENCE (2018)
Role of the immunosuppressive microenvironment in immunotherapy
Garth W. Tormoen et al.
ADVANCES IN RADIATION ONCOLOGY (2018)
How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression?
Brandon J. Aubrey et al.
CELL DEATH AND DIFFERENTIATION (2018)
Autophagy pathway: Cellular and molecular mechanisms
Li Yu et al.
AUTOPHAGY (2018)
Inflammatory signaling cascades and autophagy in cancer
Teresa Monkkonen et al.
AUTOPHAGY (2018)
Doxycycline inhibits the cancer stem cell phenotype and epithelial-to-mesenchymal transition in breast cancer
Le Zhang et al.
CELL CYCLE (2017)
Ginkgolic Acid Inhibits Invasion and Migration and TGF--Induced EMT of Lung Cancer Cells Through PI3K/Akt/mTOR Inactivation
Seung Ho Baek et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2017)
Autophagy Induction Results in Enhanced Anoikis Resistance in Models of Peritoneal Disease
James L. Chen et al.
MOLECULAR CANCER RESEARCH (2017)
Resveratrol inhibits IL-6-induced ovarian cancer cell migration through epigenetic up-regulation of autophagy
Alessandra Ferraresi et al.
MOLECULAR CARCINOGENESIS (2017)
Epithelial-mesenchymal transition in tumor metastasis
Kay T. Yeung et al.
MOLECULAR ONCOLOGY (2017)
Cadherin-6 promotes EMT and cancer metastasis by restraining autophagy
M. Gugnoni et al.
ONCOGENE (2017)
Signaling Cross Talk between TGF-beta/Smad and Other Signaling Pathways
Kunxin Luo
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)
Inhibition of PI3K/Akt/mTOR signaling in PI3KR2-overexpressing colon cancer stem cells reduces tumor growth due to apoptosis
Sugong Chen et al.
ONCOTARGET (2017)
Integrin signaling potentiates transforming growth factor-beta 1 (TGF-β1) dependent down-regulation of E-Cadherin expression - Important implications for epithelial to mesenchymal transition (EMT) in renal cell carcinoma
B. Feldkoren et al.
EXPERIMENTAL CELL RESEARCH (2017)
Inhibiting ROS-NF-κB-dependent autophagy enhanced brazilininduced apoptosis in head and neck squamous cell carcinoma
Zhi-Jing He et al.
FOOD AND CHEMICAL TOXICOLOGY (2017)
Regulation of Mitochondrial Structure and Dynamics by the Cytoskeleton and Mechanical Factors
Erzsebet Bartolak-Suki et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Regulation of autophagy and EMT by the interplay between p53 and RAS during cancer progression
Xiaofei Zhang et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2017)
TGF-β2 initiates autophagy via Smad and non-Smad pathway to promote glioma cells' invasion
Chao Zhang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2017)
Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways
Marisa Granato et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2017)
Melatonin reverses H2O2-induced senescence in SH-SY5Y cells by enhancing autophagy via sirtuin 1 deacetylation of the RelA/p65 subunit of NF-κB
Chutikorn Nopparat et al.
JOURNAL OF PINEAL RESEARCH (2017)
Cancerous perturbations within the ERK, PI3K/Akt, and Wnt/β-catenin signaling network constitutively activate inter-pathway positive feedback loops
Rahul Rao Padala et al.
MOLECULAR BIOSYSTEMS (2017)
Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function
Jun-ichi Sakamaki et al.
MOLECULAR CELL (2017)
Understanding the molecular mechanisms driving metastasis
Joan Massague et al.
MOLECULAR ONCOLOGY (2017)
Microenvironmental autophagy promotes tumour growth
Nadja S. Katheder et al.
NATURE (2017)
Autophagy suppresses Ras-driven epithelial tumourigenesis by limiting the accumulation of reactive oxygen species
J. Manent et al.
ONCOGENE (2017)
Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo
Lan Zhang et al.
CHEMICAL SCIENCE (2017)
Overaccumulation of p53-mediated autophagy protects against betulinic acid-induced apoptotic cell death in colorectal cancer cells
Sen Wang et al.
CELL DEATH & DISEASE (2017)
Calreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway
Weiwei Sheng et al.
CELL DEATH & DISEASE (2017)
MiR-23a promotes TGF-β1-induced EMT and tumor metastasis in breast cancer cells by directly targeting CDH1 and activating Wnt/β-catenin signaling
Fei Ma et al.
ONCOTARGET (2017)
Human steroid sulfatase induces Wnt/β-catenin signaling and epithelial-mesenchymal transition by upregulating Twist1 and HIF-1α in human prostate and cervical cancer cells
Sangyun Shin et al.
ONCOTARGET (2017)
NF-kappaB Is Involved in the Regulation of EMT Genes in Breast Cancer Cells
Bruno R. B. Pires et al.
PLOS ONE (2017)
Metformin transiently inhibits colorectal cancer cell proliferation as a result of either AMPK activation or increased ROS production
Angela Mogavero et al.
SCIENTIFIC REPORTS (2017)
被撤回的出版物: High Uric Acid-Induced Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells via the TLR4/NF-kB Signaling Pathway (Retracted article. See vol. 52, pg. 604, 2021)
Huifang Liu et al.
AMERICAN JOURNAL OF NEPHROLOGY (2017)
IL-6 promotes epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2/STAT3 signaling pathway
Jing Xiao et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2017)
M2 macrophages induce EMT through the TGF-/Smad2 signaling pathway
Liangying Zhu et al.
CELL BIOLOGY INTERNATIONAL (2017)
Targeting autophagy in cancer
Jean M. Mulcahy Levy et al.
NATURE REVIEWS CANCER (2017)
Bisindolylmaleimide alkaloid BMA-155Cl induces autophagy and apoptosis in human hepatocarcinoma HepG-2 cells through the NF-κB p65 pathway
Xiao Sun et al.
ACTA PHARMACOLOGICA SINICA (2017)
Inhibition of PI3K/AKT/mTOR signaling pathway promotes autophagy of articular chondrocytes and attenuates inflammatory response in rats with osteoarthritis
Jian-Feng Xue et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
Cleaning House: Selective Autophagy of Organelles
Allyson L. Anding et al.
DEVELOPMENTAL CELL (2017)
mTOR Signaling in Growth, Metabolism, and Disease
Robert A. Saxton et al.
CELL (2017)
Mosaic Disorders of the PI3K/PTEN/AKT/TSC/mTORC1 Signaling Pathway
Neera Nathan et al.
DERMATOLOGIC CLINICS (2017)
The Notch pathway in colorectal cancer
Kaitlyn E. Vinson et al.
INTERNATIONAL JOURNAL OF CANCER (2016)
Treatment of relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma with everolimus (RAD001) and alemtuzumab: a Phase I/II study
Clive S. Zent et al.
LEUKEMIA & LYMPHOMA (2016)
STAT3 integrates cooperative Ras and TGF-β signals that induce Snail expression
M. Saitoh et al.
ONCOGENE (2016)
Gsk-3β Controls Autophagy by Modulating LKB1-AMPK Pathway in Prostate Cancer Cells
Aijing Sun et al.
PROSTATE (2016)
Autophagy promotes ferroptosis by degradation of ferritin
Wen Hou et al.
AUTOPHAGY (2016)
PEBP1, a RAF kinase inhibitory protein, negatively regulates starvation-induced autophagy by direct interaction with LC3
Hae Sook Noh et al.
AUTOPHAGY (2016)
PI3K/Akt/mTOR and Ras/Raf/MEK/ERK signaling pathways inhibitors as anticancer agents: Structural and pharmacological perspectives
Vivek Asati et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
Inactivation of p53 in pterygium influence miR-200a expression resulting in ZEB1/ZEB2 up-regulation and EMT processing
Chueh-Wei Wu et al.
EXPERIMENTAL EYE RESEARCH (2016)
Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells
Jessie Yanxiang Guo et al.
GENES & DEVELOPMENT (2016)
Autophagy links β-catenin and Smad signaling to promote epithelial-mesenchymal transition via upregulation of integrin linked kinase
Min Pang et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2016)
Receptor for Activated C Kinase 1 (RACK1) Promotes Dishevelled Protein Degradation via Autophagy and Antagonizes Wnt Signaling
Minzhang Cheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Atg8 family LC3/GABARAP proteins are crucial for autophagosome-lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation
Thanh Ngoc Nguyen et al.
JOURNAL OF CELL BIOLOGY (2016)
ZEB1 drives epithelial-to-mesenchymal transition in lung cancer
Jill E. Larsen et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Cannabidiol Counteracts Amphetamine-Induced Neuronal and Behavioral Sensitization of the Mesolimbic Dopamine Pathway through a NovelmTOR/p70S6Kinase Signaling Pathway
Justine Renard et al.
JOURNAL OF NEUROSCIENCE (2016)
Autophagy Regulates Chromatin Ubiquitination in DNA Damage Response through Elimination of SQSTM1/p62
Yanan Wang et al.
MOLECULAR CELL (2016)
Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis
Jun Weil et al.
NATURE IMMUNOLOGY (2016)
The ATG conjugation systems are important for degradation of the inner autophagosomal membrane
Kotaro Tsuboyama et al.
SCIENCE (2016)
The 4E-BP-eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytes
Lomon So et al.
SCIENCE SIGNALING (2016)
Autophagy and epithelial-mesenchymal transition: an intricate interplay in cancer
Mila Gugnoni et al.
CELL DEATH & DISEASE (2016)
Inhibition of EHMT2/G9a epigenetically increases the transcription of Beclin-1 via an increase in ROS and activation of NF-κB
Sang Eun Park et al.
ONCOTARGET (2016)
Autophagy negatively regulates tumor cell proliferation through phosphorylation dependent degradation of the Notch1 intracellular domain
Ji-Seon Ahn et al.
ONCOTARGET (2016)
Lysophosphatidic acid stimulates epithelial to mesenchymal transition marker Slug/Snail2 in ovarian cancer cells via Gai2, Src, and HIF1α signaling nexus
Ji Hee Ha et al.
ONCOTARGET (2016)
Induction of epithelial-mesenchymal transition (EMT) by Beclin 1 knockdown via posttranscriptional upregulation of ZEB1 in thyroid cancer cells
Si Li et al.
ONCOTARGET (2016)
Nesfatin-1/Nucleobindin-2 enhances cell migration, invasion, and epithelial-mesenchymal transition via LKB1/AMPK/TORC1/ZEB1 pathways in colon cancer
Jung-Yu Kan et al.
ONCOTARGET (2016)
p53 in the DNA-Damage-Repair Process
Ashley B. Williams et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2016)
The 4E-BP-eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytes
Lomon So et al.
SCIENCE SIGNALING (2016)
Bafilomycin A1 induces caspase-independent cell death in hepatocellular carcinoma cells via targeting of autophagy and MAPK pathways
Yumei Yan et al.
SCIENTIFIC REPORTS (2016)
Ixabepilone: a new treatment option for the management of taxane-resistant metastatic breast cancer
Rebecca Goldstein et al.
Cancer Management and Research (2016)
Bafilomycin A1 disrupts autophagic flux by inhibiting both V-ATPase-dependent acidification and Ca-P60A/SERCA-dependent autophagosome-lysosome fusion
Caroline Mauvezin et al.
AUTOPHAGY (2015)
p53-mediated autophagic regulation: A prospective strategy for cancer therapy
Juanjuan Tang et al.
CANCER LETTERS (2015)
Autophagy, Metabolism, and Cancer
Eileen White et al.
CLINICAL CANCER RESEARCH (2015)
Modulation of Notch Signaling as a Therapeutic Approach for Liver Cancer
Guang Wu et al.
CURRENT GENE THERAPY (2015)
Function of human WIPI proteins in autophagosomal rejuvenation of endomembranes?
Amelie Johanna Mueller et al.
FEBS LETTERS (2015)
The Wnt Signaling Antagonist Dapper1 Accelerates Dishevelled2 Degradation via Promoting Its Ubiquitination and Aggregate-induced Autophagy
Benyu Ma et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
The role for autophagy in cancer
Eileen White
JOURNAL OF CLINICAL INVESTIGATION (2015)
Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates
Daniel F. Egan et al.
MOLECULAR CELL (2015)
Autophagy induction impairs migration and invasion by reversing EMT in glioblastoma cells
Myriam Catalano et al.
MOLECULAR ONCOLOGY (2015)
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
Xiaofeng Zheng et al.
NATURE (2015)
Autophagy mediates degradation of nuclear lamina
Zhixun Dou et al.
NATURE (2015)
Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism
RushikaM. Perera et al.
NATURE (2015)
Evaluation of the effects of a plasma activated medium on cancer cells
S. Mohades et al.
PHYSICS OF PLASMAS (2015)
MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells
Diego Ploper et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Autophagy Sustains Hematopoiesis Through Targeting Notch
Yan Cao et al.
STEM CELLS AND DEVELOPMENT (2015)
Metformin inhibits thyroid cancer cell growth, migration, and EMT through the mTOR pathway
Baiyu Han et al.
TUMOR BIOLOGY (2015)
Autophagy regulates hepatocyte identity and epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions promoting Snail degradation
G. Grassi et al.
CELL DEATH & DISEASE (2015)
A new role for the PI3K/Akt signaling pathway in the epithelial-mesenchymal transition
Wenting Xu et al.
CELL ADHESION & MIGRATION (2015)
Addition of rapamycin and hydroxychloroquine to metronomic chemotherapy as a second line treatment results in high salvage rates for refractory metastatic solid tumors: a pilot safety and effectiveness analysis in a small patient cohort
Kwan-Hwa Chi et al.
ONCOTARGET (2015)
Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells
Wenjie Qin et al.
ONCOTARGET (2015)
Intact LKB1 activity is required for survival of dormant ovarian cancer spheroids
Teresa Peart et al.
ONCOTARGET (2015)
Macroautophagy in endogenous processing of self- and pathogen-derived antigens for MHC class II presentation
Fernanda V. Duraes et al.
FRONTIERS IN IMMUNOLOGY (2015)
Current clinical regulation of PI3K/PTEN/Akt/mTOR signalling in treatment of human cancer
Hui Jun Lim et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2015)
AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation
Valentina Cianfanelli et al.
NATURE CELL BIOLOGY (2015)
Autophagy regulates tissue overgrowth in a context-dependent manner
E. Perez et al.
ONCOGENE (2015)
Metformin Inhibits Growth of Human Glioblastoma Cells and Enhances Therapeutic Response
Julie Sesen et al.
PLOS ONE (2015)
AMPK Inhibits the Stimulatory Effects of TGF-β on Smad2/3 Activity, Cell Migration, and Epithelial-to-Mesenchymal Transition
Hui Lin et al.
MOLECULAR PHARMACOLOGY (2015)
Chloroquine potentiates the anti-cancer effect of lidamycin on non-small cell lung cancer cells in vitro
Fang Liu et al.
ACTA PHARMACOLOGICA SINICA (2014)
An Overview of Autophagy: Morphology, Mechanism, and Regulation
Katherine R. Parzych et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Autophagic degradation of GZMB/granzyme B
Elodie Viry et al.
AUTOPHAGY (2014)
Q6, a novel hypoxia-targeted drug, regulates hypoxia-inducible factor signaling via an autophagy-dependent mechanism in hepatocellular carcinoma
Xiao-Wen Liu et al.
AUTOPHAGY (2014)
Phase I clinical trial and pharmacodynamic evaluation of combination hydroxychloroquine and doxorubicin treatment in pet dogs treated for spontaneously occurring lymphoma
Rebecca A. Barnard et al.
AUTOPHAGY (2014)
Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity
Michelle Cicchini et al.
AUTOPHAGY (2014)
Inhibition of autophagy attenuates pancreatic cancer growth independent of TP53/TRP53 status
Annan Yang et al.
AUTOPHAGY (2014)
Combined autophagy and HDAC inhibition A phase I safety, tolerability, pharmacokinetic, and pharmacodynamic analysis of hydroxychloroquine in combination with the HDAC inhibitor vorinostat in patients with advanced solid tumors
Devalingam Mahalingam et al.
AUTOPHAGY (2014)
A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme
Myrna R. Rosenfeld et al.
AUTOPHAGY (2014)
Neferine, an alkaloid from lotus seed embryo, inhibits human lung cancer cell growth by MAPK activation and cell cycle arrest
Paramasivan Poornima et al.
BIOFACTORS (2014)
Tumor Vessel Normalization by Chloroquine Independent of Autophagy
Hannelore Maes et al.
CANCER CELL (2014)
Autophagy eliminates cytoplasmic β-catenin and NICD to promote the cardiac differentiation of P19CL6 cells
Zhuqing Jia et al.
CELLULAR SIGNALLING (2014)
Hydroxychloroquine Inhibits Autophagy to Potentiate Antiestrogen Responsiveness in ER+ Breast Cancer
Katherine L. Cook et al.
CLINICAL CANCER RESEARCH (2014)
Tumor-Associated Macrophages: From Mechanisms to Therapy
Roy Noy et al.
IMMUNITY (2014)
Inhibition of mTOR pathway attenuates migration and invasion of gallbladder cancer via EMT inhibition
Huajie Zong et al.
MOLECULAR BIOLOGY REPORTS (2014)
Mutational Landscape of the Essential Autophagy Gene BECN1 in Human Cancers
Saurabh V. Laddha et al.
MOLECULAR CANCER RESEARCH (2014)
Autophagy variation within a cell population determines cell fate through selective degradation of Fap-1
Jacob M. Gump et al.
NATURE CELL BIOLOGY (2014)
Autophagy is essential for effector CD8+ T cell survival and memory formation
Xiaojin Xu et al.
NATURE IMMUNOLOGY (2014)
Chloroquine enhances temozolomide cytotoxicity in malignant gliomas by blocking autophagy
Encouse B. Golden et al.
NEUROSURGICAL FOCUS (2014)
Resveratrol Triggers Protective Autophagy Through the Ceramide/Akt/mTOR Pathway in Melanoma B16 Cells
Meng Wang et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2014)
FOXM1 Regulated by ERK Pathway Mediates TGF-β1-Induced EMT in NSCLC
Fei-Fei Kong et al.
ONCOLOGY RESEARCH (2014)
Regulation of cell proliferation and migration by p62 through stabilization of Twist1
Lei Qiang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Mutation analysis of key genes in RAS/RAF and PI3K/PTEN pathways in Chinese patients with hepatocellular carcinoma
Wenmin Hou et al.
ONCOLOGY LETTERS (2014)
Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut
Maia Chanrion et al.
NATURE COMMUNICATIONS (2014)
A dual role for autophagy in a murine model of lung cancer
Shuan Rao et al.
NATURE COMMUNICATIONS (2014)
Autophagy Is Critical for Pancreatic Tumor Growth and Progression in Tumors with p53 Alterations
Annan Yang et al.
CANCER DISCOVERY (2014)
ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-κB-dependent activation of Snail
Magdalena A. Cichon et al.
ONCOTARGET (2014)
Role of aberrant PI3K pathway activation in gallbladder tumorigenesis
Andrea Lunardi et al.
ONCOTARGET (2014)
Autophagy is a critical regulator of memory CD8+ T cell formation
Daniel J. Puleston et al.
ELIFE (2014)
Autophagy induced by p53-reactivating molecules protects pancreatic cancer cells from apoptosis
Claudia Fiorini et al.
APOPTOSIS (2013)
TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy
Pauline Isakson et al.
AUTOPHAGY (2013)
Crosstalk between apoptosis, necrosis and autophagy
Vassiliki Nikoletopoulou et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Autophagy Plays a Critical Role in the Degradation of Active RHOA, the Control of Cell Cytokinesis, and Genomic Stability
Amine Belaid et al.
CANCER RESEARCH (2013)
The Notch signaling pathway as a mediator of tumor survival
Kathleen M. Capaccione et al.
CARCINOGENESIS (2013)
Autophagy promotes hepatocellular carcinoma cell invasion through activation of epithelialmesenchymal transition
Jun Li et al.
CARCINOGENESIS (2013)
Autophagy-Mediated Tumor Promotion
Jessie Yanxiang Guo et al.
CELL (2013)
Knockdown of β-catenin controls both apoptotic and autophagic cell death through LKB1/AMPK signaling in head and neck squamous cell carcinoma cell lines
Hyo Won Chang et al.
CELLULAR SIGNALLING (2013)
Phase I Study of Panobinostat plus Everolimus in Patients with Relapsed or Refractory Lymphoma
Yasuhiro Oki et al.
CLINICAL CANCER RESEARCH (2013)
The Role of Snail in EMT and Tumorigenesis
Yifan Wang et al.
CURRENT CANCER DRUG TARGETS (2013)
TGF-beta signaling and epithelial-mesenchymal transition in cancer progression
Yoko Katsuno et al.
CURRENT OPINION IN ONCOLOGY (2013)
Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses
Daniela Kenzelmann Broz et al.
GENES & DEVELOPMENT (2013)
TIM-4 Glycoprotein-Mediated Degradation of Dying Tumor Cells by Autophagy Leads to Reduced Antigen Presentation and Increased Immune Tolerance
Muhammad Baghdadi et al.
IMMUNITY (2013)
The role of membrane-trafficking small GTPases in the regulation of autophagy
Carla F. Bento et al.
JOURNAL OF CELL SCIENCE (2013)
p53 status determines the role of autophagy in pancreatic tumour development
Mathias T. Rosenfeldt et al.
NATURE (2013)
Autophagosomes form at ER-mitochondria contact sites
Maho Hamasaki et al.
NATURE (2013)
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
Ryan C. Russell et al.
NATURE CELL BIOLOGY (2013)
The autophagosome: origins unknown, biogenesis complex
Christopher A. Lamb et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells
C. Gong et al.
ONCOGENE (2013)
Mutant p53 gain-of-function induces epithelial-mesenchymal transition through modulation of the miR-130b-ZEB1 axis
P. Dong et al.
ONCOGENE (2013)
Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment
X. Sui et al.
CELL DEATH & DISEASE (2013)
Autophagy Sustains Mitochondrial Glutamine Metabolism and Growth of BrafV600E-Driven Lung Tumors
Anne M. Strohecker et al.
CANCER DISCOVERY (2013)
PI3K/Akt Signaling Interacts With Wnt/β-Catenin Signaling But Does Not Induce An Accumulation of β-Catenin In The Nucleus Of Acute Lymphoblastic Leukemia Cell Lines
Tina-Susann Langhammer et al.
BLOOD (2013)
AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets
Ken Inoki et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 52 (2012)
Low expression of Beclin 1, associated with high Bcl-xL, predicts a malignant phenotype and poor prognosis of gastric cancer
Wei-Hua Zhou et al.
AUTOPHAGY (2012)
The roles of BECN1 and autophagy in cancer are context dependent
Chang Gong et al.
AUTOPHAGY (2012)
A novel method for autophagy detection in primary cells Impaired levels of macroautophagy in immunosenescent T cells
Kanchan Phadwal et al.
AUTOPHAGY (2012)
Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy
Paola Maycotte et al.
AUTOPHAGY (2012)
The lack of autophagy triggers precocious activation of Notch signaling during Drosophila oogenesis
Julia M. I. Barth et al.
BMC DEVELOPMENTAL BIOLOGY (2012)
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
Douglas Hanahan et al.
CANCER CELL (2012)
Phase I study of bevacizumab, everolimus, and panobinostat (LBH-589) in advanced solid tumors
John H. Strickler et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2012)
DEDD Interacts with PI3KC3 to Activate Autophagy and Attenuate Epithelial-Mesenchymal Transition in Human Breast Cancer
Qi Lv et al.
CANCER RESEARCH (2012)
Tumor Microenvironment Complexity: Emerging Roles in Cancer Therapy
Melody A. Swartz et al.
CANCER RESEARCH (2012)
The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes
Eisuke Itakura et al.
CELL (2012)
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Scott J. Dixon et al.
CELL (2012)
Wnt/β-Catenin Signaling and Disease
Hans Clevers et al.
CELL (2012)
Metabolic remodeling of the tumor microenvironment Migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth
Valentina Carito et al.
CELL CYCLE (2012)
The translational landscape of mTOR signalling steers cancer initiation and metastasis
Andrew C. Hsieh et al.
NATURE (2012)
Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency
Quentin McAfee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Deconvoluting the context-dependent role for autophagy in cancer
Eileen White
NATURE REVIEWS CANCER (2012)
The Role of Atg Proteins in Autophagosome Formation
Noboru Mizushima et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
Quercetin induces protective autophagy in gastric cancer cells Involvement of Akt-mTOR- and hypoxia-induced factor 1α-mediated signaling
Kui Wang et al.
AUTOPHAGY (2011)
Role of Autophagy in Cancer Prevention
Hsin-Yi Chen et al.
CANCER PREVENTION RESEARCH (2011)
Autophagic Survival in Resistance to Histone Deacetylase Inhibitors: Novel Strategies to Treat Malignant Peripheral Nerve Sheath Tumors
Gonzalo Lopez et al.
CANCER RESEARCH (2011)
GABARAPL1 Negatively Regulates Wnt/beta-catenin Signaling by Mediating Dvl2 Degradation through the Autophagy Pathway
Yanquan Zhang et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2011)
Pancreatic cancers require autophagy for tumor growth
Shenghong Yang et al.
GENES & DEVELOPMENT (2011)
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
Jessie Yanxiang Guo et al.
GENES & DEVELOPMENT (2011)
Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways
Michela Palmieri et al.
HUMAN MOLECULAR GENETICS (2011)
Kinetics Comparisons of Mammalian Atg4 Homologues Indicate Selective Preferences toward Diverse Atg8 Substrates
Min Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2
Taewan Kim et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
A Role for Autophagic Protein Beclin 1 Early in Lymphocyte Development
Ivica Arsov et al.
JOURNAL OF IMMUNOLOGY (2011)
Arsenic trioxide induces autophagy and apoptosis in human glioma cells in vitro and in vivo through downregulation of survivin
Hui-Wen Chiu et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2011)
Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity
Tse-Chun Kuo et al.
NATURE CELL BIOLOGY (2011)
p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs
Chun-Ju Chang et al.
NATURE CELL BIOLOGY (2011)
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
Joungmok Kim et al.
NATURE CELL BIOLOGY (2011)
Targeting cancer stem cells by inhibiting Wnt, notch, and Hedgehog pathways
Naoko Takebe et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2011)
mTOR: from growth signal integration to cancer, diabetes and ageing
Roberto Zoncu et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice
Mickael Michaud et al.
SCIENCE (2011)
TFEB Links Autophagy to Lysosomal Biogenesis
Carmine Settembre et al.
SCIENCE (2011)
Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging
Douglas R. Green et al.
SCIENCE (2011)
A Perspective on Cancer Cell Metastasis
Christine L. Chaffer et al.
SCIENCE (2011)
Atg8: an autophagy-related ubiquitin-like protein family
Tomer Shpilka et al.
GENOME BIOLOGY (2011)
The Tor and cAMP-dependent protein kinase signaling pathways coordinately control autophagy in Saccharomyces cerevisiae
Joseph S. Stephan et al.
AUTOPHAGY (2010)
Regulation of autophagy by transforming growth factor-β (TGFβ) signaling
Hiroshi I. Suzuki et al.
AUTOPHAGY (2010)
Genetic and epigenetic silencing of the beclin 1 gene in sporadic breast tumors
Zidong Li et al.
BMC CANCER (2010)
Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells
Kazuhito Sasaki et al.
BMC CANCER (2010)
NF-κB promotes epithelial-mesenchynmal transition, migration and invasion of pancreatic carcinoma cells
Harald J. Maier et al.
CANCER LETTERS (2010)
Quantitative In vivo Imaging of the Effects of Inhibiting Integrin Signaling via Src and FAK on Cancer Cell Movement: Effects on E-cadherin Dynamics
Marta Canel et al.
CANCER RESEARCH (2010)
Dishevelled-DEP domain interacting protein (DDIP) inhibits Wnt signaling by promoting TCF4 degradation and disrupting the TCF4/β-catenin complex
Haiwei Zhang et al.
CELLULAR SIGNALLING (2010)
TOR-dependent control of autophagy: biting the hand that feeds
Thomas P. Neufeld
CURRENT OPINION IN CELL BIOLOGY (2010)
Autophagy regulation by p53
Maria Chiara Maiuri et al.
CURRENT OPINION IN CELL BIOLOGY (2010)
Mammalian autophagy: core molecular machinery and signaling regulation
Zhifen Yang et al.
CURRENT OPINION IN CELL BIOLOGY (2010)
PKA phosphorylates and inactivates AMPKα to promote efficient lipolysis
Nabil Djouder et al.
EMBO JOURNAL (2010)
Regulation of autophagy by phosphatidylinositol 3-phosphate
Chloe Burman et al.
FEBS LETTERS (2010)
Regulation of the autophagy protein LC3 by phosphorylation
Salvatore J. Cherra et al.
JOURNAL OF CELL BIOLOGY (2010)
Combinational Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor Proteins VAMP8 and Vti1b Mediate Fusion of Antimicrobial and Canonical Autophagosomes with Lysosomes
Nobumichi Furuta et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
cAMP-Dependent Activation of Mammalian Target of Rapamycin (mTOR) in Thyroid Cells. Implication in Mitogenesis and Activation of CDK4
Sara Blancquaert et al.
MOLECULAR ENDOCRINOLOGY (2010)
Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation
Chan Gao et al.
NATURE CELL BIOLOGY (2010)
Transforming growth factor-β-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression
M. K. Wendt et al.
ONCOGENE (2010)
Regulation Mechanisms and Signaling Pathways of Autophagy
Congcong He et al.
ANNUAL REVIEW OF GENETICS (2009)
TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways
Claudio Marcelo Fader et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
Stabilization of Snail by NF-κB Is Required for Inflammation-Induced Cell Migration and Invasion
Yadi Wu et al.
CANCER CELL (2009)
Autophagy Suppresses Tumorigenesis through Elimination of p62
Robin Mathew et al.
CELL (2009)
The Double-Edged Sword of Autophagy Modulation in Cancer
Eileen White et al.
CLINICAL CANCER RESEARCH (2009)
Stat3 Is Involved in Angiotensin II-Induced Expression of MMP2 in Gastric Cancer Cells
Wei Huang et al.
DIGESTIVE DISEASES AND SCIENCES (2009)
Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: Association with MMP-9
Jing-song Chen et al.
HEPATOLOGY RESEARCH (2009)
Nutrient-dependent mTORC1 Association with the ULK1-Atg13-FIP200 Complex Required for Autophagy
Nao Hosokawa et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
Chang Hwa Jung et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Transforming growth factor-beta signaling in epithelial-mesenchymal transition and progression of cancer
Kohei Miyazono
PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES (2009)
The Tor and PKA signaling pathways independently target the Atg1/Atg13 protein kinase complex to control autophagy
Joseph S. Stephan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
The epithelial-mesenchymal transition generates cells with properties of stem cells
Sendurai A. Mani et al.
CELL (2008)
The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function
Keisuke Obara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
Taichi Hara et al.
JOURNAL OF CELL BIOLOGY (2008)
AMPK phosphorylation of raptor mediates a metabolic checkpoint
Dana M. Gwinn et al.
MOLECULAR CELL (2008)
Autophagy fights disease through cellular self-digestion
Noboru Mizushima et al.
NATURE (2008)
p53: The Janus of autophagy?
Beth Levine et al.
NATURE CELL BIOLOGY (2008)
Regulation of autophagy by cytoplasmic p53
Ezgi Tasdemir et al.
NATURE CELL BIOLOGY (2008)
Sorafenib in advanced hepatocellular carcinoma
Josep M. Llovet et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
The autophagy effector Beclin 1: a novel BH3-only protein
S. Sinha et al.
ONCOGENE (2008)
Autophagy: from phenomenology to molecular understanding in less than a decade
Daniel J. Klionsky
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Autophagosome formation: Core machinery and adaptations
Zhiping Xie et al.
NATURE CELL BIOLOGY (2007)
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
Yoshinori Takahashi et al.
NATURE CELL BIOLOGY (2007)
Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression
Hui-Wen Lo et al.
CANCER RESEARCH (2007)
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy
D. Grahame Hardie
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Nelfinavir, a lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo
JoellJ. Gills et al.
CLINICAL CANCER RESEARCH (2007)
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis
Vassiliki Karantza-Wadsworth et al.
GENES & DEVELOPMENT (2007)
Snail, ZEB and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
Hector Peinado et al.
NATURE REVIEWS CANCER (2007)
Autophagy suppresses tumor progression by limiting chromosomal instability
Robin Mathew et al.
GENES & DEVELOPMENT (2007)
Metastasis: recent discoveries and novel treatment strategies
Suzanne A. Eccles et al.
LANCET (2007)
A critical role for the autophagy gene Atg5 in T cell survival and proliferation
Heather H. Pua et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
AMP-activated protein kinase and the regulation of autophagic proteolysis
Daniel Meley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Depletion of type IA regulatory subunit (RIα) of protein kinase A (PKA) in mammalian cells and tissues activates mTOR and causes autophagic deficiency
Manos Mavrakis et al.
HUMAN MOLECULAR GENETICS (2006)
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
Chengyu Liang et al.
NATURE CELL BIOLOGY (2006)
ILK over-expression in human colon cancer progression correlates with activation of beta-catenin, down-regulation of E-cadherin and activation of the Akt-FKHR pathway
V Bravou et al.
JOURNAL OF PATHOLOGY (2006)
DNA damage-induced cell death by apoptosis
Wynand P. Roos et al.
TRENDS IN MOLECULAR MEDICINE (2006)
Molecular requirements for epithelial-mesenchymal transition during tumor progression
MA Huber et al.
CURRENT OPINION IN CELL BIOLOGY (2005)
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
S Pattingre et al.
CELL (2005)
Autophagy promotes MHC class II presentation of peptides from intracellular source proteins
J Dengjel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis
TX Xie et al.
ONCOGENE (2004)
Activation of the Erk pathway is required for TGF-β1-induced EMT in vitro
X Lu et al.
NEOPLASIA (2004)
The role of autophagy during the early neonatal starvation period
A Kuma et al.
NATURE (2004)
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
MG Gutierrez et al.
CELL (2004)
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
LA Timmerman et al.
GENES & DEVELOPMENT (2004)
TGF beta and Wnt pathway cross-talk
L Attisano et al.
CANCER AND METASTASIS REVIEWS (2004)
The Ras/cAMP-dependent protein kinase signaling pathway regulates an early step of the autophagy process in Saccharomyces cerevisiae
YV Budovskaya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
ZY Yue et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
TSC2 mediates cellular energy response to control cell growth and survival
K Inoki et al.
CELL (2003)
The snail superfamily of zinc-finger transcription factors
MA Nieto
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway
S Arico et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway
T Kirisako et al.
JOURNAL OF CELL BIOLOGY (2000)
The transcription factor Snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
A Cano et al.
NATURE CELL BIOLOGY (2000)
The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells
E Batlle et al.
NATURE CELL BIOLOGY (2000)
Share Paper
