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ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)
Peptide nucleic acids with a structurally biased backbone: Effects of conformational constraints and stereochemistry
Roberto Corradini et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2007)
Cell-permeable peptide nucleic acid designed to bind to the 5′-untranslated region of E-cadherin transcript induces potent and sequence-specific antisense effects
Anca Dragulescu-Andrasi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents
Said Abes et al.
JOURNAL OF CONTROLLED RELEASE (2006)
Structural diversity of target-specific homopyrimidine peptide nucleic acid-dsDNA complexes
Thomas Bentin et al.
NUCLEIC ACIDS RESEARCH (2006)
A simple γ-backbone modification preorganizes peptide nucleic acid into a helical structure
Anca Dragulescu-Andrasi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
Fluorescent PNA probes as hybridization labels for biological RNA
Kelly L. Robertson et al.
BIOCHEMISTRY (2006)
Hybridization of pyrrolidinyl peptide nucleic acids and DNA: Selectivity, base-pairing specificity, and direction of binding
T Vilaivan et al.
ORGANIC LETTERS (2006)
Enhanced delivery of cell-penetrating peptide-peptide nucleic acid conjugates by endosomal disruption
Takehiko Shiraishi et al.
NATURE PROTOCOLS (2006)
Synthesis of γ-substituted peptide nucleic acids: A new place to attach fluorophores without affecting DNA binding
EA Englund et al.
ORGANIC LETTERS (2005)
Conformationally constrained PNA analogues: Structural evolution toward DNA/RNA binding selectivity
VA Kumar et al.
ACCOUNTS OF CHEMICAL RESEARCH (2005)
(SR/RS)-cyclohexanyl PNAs: Conformationally preorganized PNA analogues with unprecedented preference for duplex formation with RNA
T Govindaraju et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Crystal structure of a partly self-complementary peptide nucleic acid (PNA) oligomer showing a duplex-triplex network
B Petersson et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Therapeutically promising PNA complementary to a regulatory sequence for c-myc: Pharmacokinetics in an animal model of human Burkitt's lymphoma
LC Boffa et al.
OLIGONUCLEOTIDES (2005)
A PNA-transportan conjugate targeted to the TAR region of the HIV-1 genome exhibits both antiviral and virucidal properties
B Chaubey et al.
VIROLOGY (2005)
Forced intercalation probes (FIT probes): Thiazole orange as a fluorescent base in peptide nucleic acids for homogeneous single-nucleotide-polymorphism detection
O Kohler et al.
CHEMBIOCHEM (2005)
Cell-penetrating peptide conjugates of peptide nucleic acids (PNA) as inhibitors of HIV-1 Tat-dependent trans-activation in cells
JJ Turner et al.
NUCLEIC ACIDS RESEARCH (2005)
Four base recognition by triplex-forming oligonucleotides at physiological pH
DA Rusling et al.
NUCLEIC ACIDS RESEARCH (2005)
Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA
A Dragulescu-Andrasi et al.
CHEMICAL COMMUNICATIONS (2005)
cis-cyclopentyl PNA (cpPNA) as constrained chiral PNA analogues:: stereochemical dependence of DNA/RNA hybridization
T Govindaraju et al.
CHEMICAL COMMUNICATIONS (2004)
Synthesis and evaluation of (1S,2R/1R,2S)-aminocyclohexylglycyl PNAs as conformationally preorganized PNA analogues for DNA/RNA recognition
T Govindaraju et al.
JOURNAL OF ORGANIC CHEMISTRY (2004)
Formation and stability of a Janus-Wedge type of DNA triplex
DL Chen et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
A peptide nucleic acid-neamine conjugate that targets and cleaves HIV-1 TAR RNA inhibits viral replication
E Riguet et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
(1S,2R/1R,2S)-cis-cyclopentyl PNAs (cpPNAs) as constrained PNA analogues:: Synthesis and evaluation of aeg-cpPNA chimera and stereopreferences in hybridization with DNA/RNA
T Govindaraju et al.
JOURNAL OF ORGANIC CHEMISTRY (2004)
(S,S)-trans-cyclopentane-constrained peptide nucleic acids.: A general backbone modification that improves binding affinity and sequence specificity
JK Pokorski et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Intracellular uptake and inhibition of gene expression by PNAs and PNA-peptide conjugates
K Kaihatsu et al.
BIOCHEMISTRY (2004)
A PNA4 quadruplex
Y Krishnan-Ghosh et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Identification and functional validation of PNAs that inhibit murine CD40 expression by redirection of splicing
AM Siwkowski et al.
NUCLEIC ACIDS RESEARCH (2004)
Combined triplex/duplex invasion of double-stranded DNA by tail-clamp peptide nucleic acid
T Bentin et al.
BIOCHEMISTRY (2003)
Insights into peptide nucleic acid (PNA) structural features: The crystal structure of a D-lysine-based chiral PNA-DNA duplex
V Menchise et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
(1S,2R/1R,2S)-aminocyclohexyl glycyl thymine PNA:: Synthesis, monomer crystal structures, and DNA/RNA hybridization studies
T Govindaraju et al.
ORGANIC LETTERS (2003)
A cyclopentane conformational restraint for a peptide nucleic acid: Design, asymmetric synthesis, and improved binding affinity to DNA and RNA
MC Myers et al.
ORGANIC LETTERS (2003)
Novel binding and efficient cellular uptake of guanidine-based peptide nucleic acids (GPNA)
P Zhou et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
A targeted peptide nucleic acid to down-regulate mouse microsomal triglyceride transfer protein expression in hepatocytes
SMW van Rossenberg et al.
BIOCONJUGATE CHEMISTRY (2003)
High-affinity peptide nucleic acid oligomers containing tricyclic cytosine analogues
KG Rajeev et al.
ORGANIC LETTERS (2002)
Systemically delivered antisense oligomers upregulate gene expression in mouse tissues
P Sazani et al.
NATURE BIOTECHNOLOGY (2002)
1,8-Naphthyridin-2,7-(1,8H)-dione is an effective mimic of protonated cytosine in peptide nucleic acid triplex recognition systems
C Christensen et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2002)
A novel pyrrolidinyl PNA showing high sequence specificity and preferential binding to DNA over RNA
T Vilaivan et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
Substituted 1,8-naphthyridin-2(1H)-ones are superior to thymine in the recognition of adenine in duplex as well as triplex structures
AB Eldrup et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
Pharmacokinetics and tissue distribution of a peptide nucleic acid after intravenous administration
BM McMahon et al.
ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT (2002)
Cell-dependent differential cellular uptake of PNA, peptides, and PNA-peptide conjugates
U Koppelhus et al.
ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT (2002)
Hybridization of DNA and PNA molecular beacons to single-stranded and double-stranded DNA targets
H Kuhn et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
Rolling-circle amplification under topological constraints
H Kuhn et al.
NUCLEIC ACIDS RESEARCH (2002)
Design of a targeted peptide nucleic acid prodrug to inhibit hepatic human microsomal triglyceride transfer protein expression in hepatocytes
EAL Biessen et al.
BIOCONJUGATE CHEMISTRY (2002)
Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs
P Sazani et al.
NUCLEIC ACIDS RESEARCH (2001)
Incorporation of a novel nucleobase allows stable oligonucleotide-directed triple helix formation at the target sequence containing a purine•pyrimidine interruption
D Guianvarc'h et al.
CHEMICAL COMMUNICATIONS (2001)
Peptide nucleic acids are potent modulators of endogenous pre-mRNA splicing of the murine interleukin-5 receptor-α chain
JG Karras et al.
BIOCHEMISTRY (2001)
Liver cell specific targeting of peptide nucleic acid oligomers
X Zhang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2001)
A novel method for detecting HIV-1 by non-radioactive in situ hybridization:: application of a peptide nucleic acid probe and catalysed signal amplification
T Murakami et al.
JOURNAL OF PATHOLOGY (2001)
Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease
A Muratovska et al.
NUCLEIC ACIDS RESEARCH (2001)
Bactericidal antisense effects of peptide-PNA conjugates
L Good et al.
NATURE BIOTECHNOLOGY (2001)
Free-probe fluorescence of light-up probes
N Svanvik et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2001)
Inhibition of gene expression inside cells by peptide nucleic acids: Effect of mRNA target sequence, mismatched bases, and PNA length
DF Doyle et al.
BIOCHEMISTRY (2001)
Detection of PCR products in real time using light-up probes
N Svanvik et al.
ANALYTICAL BIOCHEMISTRY (2000)
Antisense PNA effects in Escherichia coli are limited by the outer-membrane LPS layer
L Good et al.
MICROBIOLOGY-SGM (2000)
Light-up probes: Thiazole orange-conjugated peptide nucleic acid for detection of target nucleic acid in homogeneous solution
N Svanvik et al.
ANALYTICAL BIOCHEMISTRY (2000)
Effects in live cells of a c-myc anti-gene PNA linked to a nuclear localization signal
G Cutrona et al.
NATURE BIOTECHNOLOGY (2000)
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