Journal
AUTOIMMUNITY REVIEWS
Volume 20, Issue 9, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.autrev.2021.102883
Keywords
COVID-19; Chronic fatigue; Cytokine storm; Inflammatory arthritis; Long COVID; Systemic Lupus Erythematous; Vasculitis; Vasculopathy; Viral arthritis
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COVID-19 infection can lead to various rheumatological complications such as inflammatory arthritis, SLE and renal disease, vasculitis, rhabdomyolysis, and myositis. Evidence of large vessel vasculitis has also been reported in 'long COVID' patients.
Introduction: COVID-19 has caused unprecedented hardships in the 21st century with more than 150 million infections. Various immunological phenomena have been described during the course of the infection, and this infection has also triggered autoimmunity. Rheumatological illnesses have been described following resolution of the acute infection; hence we sought to conduct a review of the rheumatological complications of COVID-19. Methods: We conducted a literature search for articles relating to sequelae of COVID-19 from Jan 2020 to 30th April 2021. Results: We found a number of reports of inflammatory arthritis after SARS-CoV-2 infection. SLE and renal disease have been described, and vasculitis also appears to be a common complication. Rhabdomyolysis and myositis has also been reported in a number of patients. We also found some evidence of large vessel vasculitis in 'long COVID' patients. Conclusions: This review highlights a number of important complications such as inflammatory arthritis, lupuslike disease, myostis and vasculitis following SARS-CoV-2 infection.
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