Yarrowia lipolytica, health benefits for animals

The yeast Yarrowia lipolytica has been industrially adopted for docosahexaenoic acid and eicosapentaenoic acid production under good manufacturing practices over 2 decades. In recent years, it has claimed attention for novel biotechnological applications, such as a functional feed additive for animals. Studies have demonstrated that this yeast is safe and has probiotic and nutritional properties for mammals, birds, fish, crustaceans, and molluscs. Animals fed Y. lipolytica enhanced productive and immune parameters, as well as modulated microbiome, fatty acid composition, and biochemical profiles. Additionally, some Y. lipolytica-derived compounds have improved productive performance, immune status, and disease resistance in animals. Therefore, the aim of this review is to identify and discuss research advances on the potential use of this yeast for animals of economic interest. Challenges, opportunities, and trends were identified and envisioned in the near future for this industrially produced yeast.

Automated summary

Yarrowia lipolytica has been industrially used for over two decades to produce docosahexaenoic acid and eicosapentaenoic acid, and is now gaining attention for its potential use as a functional feed additive for animals. Studies have shown that this yeast is safe, has probiotic and nutritional properties, and can enhance productive and immune parameters in various animals. Additionally, compounds derived from Y. lipolytica have shown improvements in productive performance, immune status, and disease resistance in animals, indicating promising opportunities for its future applications in the animal industry.