Journal
APPLIED INTELLIGENCE
Volume 52, Issue 6, Pages 6340-6353Publisher
SPRINGER
DOI: 10.1007/s10489-021-02691-x
Keywords
COVID-19; Automatic segmentation; Computed tomography; Domain adaptation; Adversarial training
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This paper presents an unsupervised domain adaptation based segmentation network method, which combines synthetic data and limited unlabeled real data to improve the segmentation performance of infection areas in COVID-19 CT images. Experimental results demonstrate that this method achieves state-of-the-art segmentation performance on COVID-19 CT images.
Automatic segmentation of infection areas in computed tomography (CT) images has proven to be an effective diagnostic approach for COVID-19. However, due to the limited number of pixel-level annotated medical images, accurate segmentation remains a major challenge. In this paper, we propose an unsupervised domain adaptation based segmentation network to improve the segmentation performance of the infection areas in COVID-19 CT images. In particular, we propose to utilize the synthetic data and limited unlabeled real COVID-19 CT images to jointly train the segmentation network. Furthermore, we develop a novel domain adaptation module, which is used to align the two domains and effectively improve the segmentation network's generalization capability to the real domain. Besides, we propose an unsupervised adversarial training scheme, which encourages the segmentation network to learn the domain-invariant feature, so that the robust feature can be used for segmentation. Experimental results demonstrate that our method can achieve state-of-the-art segmentation performance on COVID-19 CT images.
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