Comparison of Dose Distribution Between VMAT-SBRT and Scanning Carbon-ion Radiotherapy for Early-stage NSCLC

Background/Aim: The purpose of this study was to compare the dose distribution between scanning carbon ion radiotherapy (sCIRT) and volumetric-modulated arc therapy with stereotactic body radiation therapy (VMATSBRT) for stage I non-small cell lung cancer (NSCLC). Patients and Methods: Fifteen patients with early-stage NSCLC who underwent sCIRT at Kanagawa Cancer Center between 2018-2020 were enrolled. Dose-volume histogram parameters of the planned target volume and normal organs for sCIRT and VMAT-SBRT were evaluated. Results: The homogeneity index of the target volume of sCIRT was significantly lower than that of VMAT-SBRT. The dose of sCIRT was significantly lower than that of VMAT-SBRT at low volumes in the lung, heart, spinal cord, and esophagus. Conclusion: The dose distribution of sCIRT for early-stage NSCLC was better than that of VMAT-SBRT.

Automated summary

In this study, scanning carbon ion radiotherapy (sCIRT) showed better dose distribution and lower dose compared to volumetric-modulated arc therapy with stereotactic body radiation therapy (VMAT-SBRT) for stage I non-small cell lung cancer patients.