Journal
EUROSURVEILLANCE
Volume 21, Issue 26, Pages 2-6Publisher
EUR CENTRE DIS PREVENTION & CONTROL
DOI: 10.2807/1560-7917.ES.2016.21.26.30270
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Funding
- FCT/MEC (Fundacao para a Ciencia e a Tecnologia / Ministerio da Educacao e Ciencia)
- FEDER [UID/MULTI/04378/2013 - POCI/01/0145/FERDER/007728]
- Fundacao para a Ciencia e a Tecnologia [SFRH/BD/93091/2013]
- Fundação para a Ciência e a Tecnologia [SFRH/BD/93091/2013] Funding Source: FCT
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The mcr-1 gene was found in 11 isolates from a Portuguese Salmonella collection (n = 1,010; 58 serotypes; 2002-15) of clinical samples, foodstuff, food-animals and water. Mcr-1 has been located on different plasmids (IncX4/IncHI2) in pig-associated multidrug-resistant, copper-tolerant S.1,4,[5], 12: i:-/ST34 and S. Rissen/ST469 clones from human and pork products since at least 2011. Our data highlight dissemination of mcr-1 by successful resistant clones in Europe and raise questions about the efficacy of copper-based interventions to reduce colistin use.
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