Decarboxylative Hydroxylation of Benzoic Acids

Herein, we report the first decarboxylative hydroxylation to synthesize phenols from benzoic acids at 35 degrees C via photoinduced ligand-to-metal charge transfer (LMCT)-enabled radical decarboxylative carbometalation. The aromatic decarboxylative hydroxylation is synthetically promising due to its mild conditions, broad substrate scope, and late-stage applications.

Automated summary

In this study, a novel method for synthesizing phenols from benzoic acids via photoinduced radical decarboxylation was reported. The method offers mild conditions, broad substrate scope, and potential for late-stage applications.