4.3 Article

A Randomized Trial of Home Blood-Pressure Reduction by Alcohol Guidance During Outpatient Visits: OSAKE Study

Journal

AMERICAN JOURNAL OF HYPERTENSION
Volume 34, Issue 10, Pages 1108-1115

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/ajh/hpab082

Keywords

alcohol guidance; blood pressure; home morning blood pressure; hypertension; outpatient

Funding

  1. Japan Heart Foundation
  2. Japanese Society of Cardiovascular Disease Prevention
  3. AstraZeneca K.K.
  4. Omron Healthcare

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The study showed that nurse-led alcohol guidance was effective in controlling home blood pressure in male patients with hypertension during outpatient visits, leading to a reduction in alcohol consumption.
BACKGROUND To evaluate the effectiveness of the nurse-led alcohol guidance to control home blood pressure (HBP) in the morning among male patients with hypertension during outpatient visits. METHODS We enrolled 53 male patients with an HBP of >= 135/85 mm Hg with excessive drinking (alcohol >= 210 g/week or >= 60 g/day habitually) among outpatients in a randomized trial. Patients were assigned to a nurse-led alcohol guidance intervention or to the control. The primary outcomes were the mean HBP of 5 consecutive days at 6 months and alcohol consumption. RESULTS Twenty-eight and 25 patients were randomized to intervention and control groups, respectively (mean age; 62.7 years old and 64.5, respectively). At baseline, the groups were well balanced across most characteristics. At 6 months, the mean HBP was 131/82 mm Hg in the intervention group vs. 145/87 mm Hg in the control group (SBP <0.001, DBP = 0.09). An HBP level of less than 135/85 mm Hg was achieved among 55.6% of the participants in the intervention group vs. 16.7% in the control group (P = 0.004). The alcohol consumption at 6 months was 256 206 g/w vs. 413 260 g/w, respectively (P = 0.020). CONCLUSIONS We confirmed the effectiveness of the nurse-led alcohol guidance to control the HBP in male patients with hypertension during outpatient visits.

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