Journal
AMERICAN JOURNAL OF DERMATOPATHOLOGY
Volume 44, Issue 2, Pages E19-E22Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/DAD.0000000000002048
Keywords
Epstein-Barr virus; immunodeficiency; cutaneous T-cell lymphoma; adalimumab
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This is a rare case of EBV-positive T-cell lymphoma presenting in the skin of a 32-year-old woman using adalimumab for neurosarcoidosis.
Immunodeficiency-associated lymphoproliferative disorders are associated with latent infection by Epstein-Barr virus (EBV). Most cases of EBV-positive immunodeficiency-associated lymphoproliferative disorders arise from B cells, although some are of T-cell or natural killer origin. Cutaneous involvement is unusual and sporadically reported in the literature. We describe a rare case of an EBV-positive T-cell lymphoma presenting in the skin of a 32-year-old woman using adalimumab for neurosarcoidosis.
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