Journal
AIDS PATIENT CARE AND STDS
Volume 35, Issue 7, Pages 255-262Publisher
MARY ANN LIEBERT, INC
DOI: 10.1089/apc.2021.0031
Keywords
HIV; preexposure prophylaxis; emergency medicine
Funding
- Alabama Department of Public Health [C00119100]
- CDC
- public health service award
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Through studying HIV seroconverters in the emergency department, it was revealed that certain populations are disproportionately affected by race, history of intravenous drug use, mental health comorbidities, and lack of social factors. The findings suggest that the emergency department could provide a unique opportunity for intervention before HIV exposure, particularly for vulnerable populations.
The emergency department (ED) may represent a missed opportunity to proactively intervene upon patients at high risk for HIV. We sought to describe characteristics of ED HIV seroconverters (individuals who screened positive in the ED for HIV who had either (1) a previous prior negative HIV test in the electronic health record (EHR) or who (2) self-reported a prior negative HIV test) to identify a high-risk phenotype for pre-infection engagement. A retrospective chart-review was performed of HIV seroconverters at an academic, urban ED. General demographics, mental health illness comorbidities, and Centers for Disease Control and Prevention (CDC)-identified high risk factors, including intravenous drug use (IVDU) and history of sexually transmitted infection (STI) were noted. One hundred thirty total patients were identified, 48 (36.9%) with prior HER-negative test and 82 (63.1%) with self-reported previous negative test. Of total seroconverters: 100 (76.9%) were male and 77 (59.2%) were between the ages of 13-34, comparable to national rates of new HIV diagnoses. Ninety-two patients (70.8%) were Black and 16 (12.3%) had a history of IVDU, significantly increased compared with regional and national new HIV rates (p < 0.05). Fifty-two patients (40%) had an STI within 1 year before HIV-positive screen, 67 (51.5%) had a history of mental health illness, and 77 (59.2%) were uninsured. This review revealed an HIV seroconversion population disproportionately affected by race, IVDU, mental health comorbidities, and additional social factors. The ED may represent a unique opportunity for at-risk, pre-HIV exposure intervention, particularly for vulnerable populations.
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