4.7 Review

Imaging cancer cells with nanostructures: Prospects of nanotechnology driven non-invasive cancer diagnosis

Journal

ADVANCES IN COLLOID AND INTERFACE SCIENCE
Volume 294, Issue -, Pages -

Publisher

ELSEVIER
DOI: 10.1016/j.cis.2021.102457

Keywords

Nanotechnology; Cancer detection; Diagnosis; Quantum dots; Graphene oxide; Biomarkers; MRI; CT; Ultrasound

Funding

  1. Qatar National Research Fund (a part of Qatar Foundation) [NPRP10-0120-170211, NPRP12S-0310-190276]

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The application of nanostructured materials in medicine, particularly in cancer diagnosis, shows great promise in aiding early detection, treatment, and patient follow-up. The tunable physical, chemical, and biological properties of nanomaterials make them highly desirable for diagnosing and treating various diseases, including cancers.
The application of nanostructured materials in medicine is a rapidly evolving area of research that includes both the diagnosis and treatment of various diseases. Metals, metal oxides and carbon-based nanomaterials have shown much promise in medical technological advancements due to their tunable physical, chemical and biological properties. The nanoscale properties, especially the size, shape, surface chemistry and stability makes them highly desirable for diagnosing and treating various diseases, including cancers. Major applications of nanomaterials in cancer diagnosis include in vivo bioimaging and molecular marker detection, mainly as image contrast agents using modalities such as radio, magnetic resonance, and ultrasound imaging. When a suitable targeting ligand is attached on the nanomaterial surface, it can help pinpoint the disease site during imaging. The application of nanostructured materials in cancer diagnosis can help in the early detection, treatment and patient follow-up. This review aims to gather and present the information regarding the application of nanotechnology in cancer diagnosis. We also discuss the challenges and prospects regarding the application of nanomaterials as cancer diagnostic tools.

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