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CRISPR/Cas9-mediated knockout of c-REL in HeLa cells results in profound defects of the cell cycle
Carsten Slotta et al.
PLOS ONE (2017)
Lentiviral CRISPR/Cas9 nickase vector mediated BIRC5 editing inhibits epithelial to mesenchymal transition in ovarian cancer cells
Guannan Zhao et al.
ONCOTARGET (2017)
Overexpression of the transcription factor ATF3 with a regulatory molecular signature associates with the pathogenic development of colorectal cancer
Feng Yan et al.
ONCOTARGET (2017)
PD-1 and PD-L1 Checkpoint Signaling Inhibition for Cancer Immunotherapy: Mechanism, Combinations, and Clinical Outcome
Hashem O. Alsaab et al.
FRONTIERS IN PHARMACOLOGY (2017)
Genome Editing for Cancer Therapy: Delivery of Cas9 Protein/sgRNA Plasmid via a Gold Nanocluster/Lipid Core-Shell Nanocarrier
Peng Wang et al.
ADVANCED SCIENCE (2017)
Exploring the Role of RGD-Recognizing Integrins in Cancer
Markus Nieberler et al.
CANCERS (2017)
Tumor-Targeted Accumulation of Ligand-Installed Polymeric Micelles Influenced by Surface PEGylation Crowdedness
Xi Yang et al.
ACS APPLIED MATERIALS & INTERFACES (2017)
Advances in Functionalized Mesoporous Silica Nanoparticles for Tumor Targeted Drug Delivery and Theranostics
Wenjia Zhang et al.
CURRENT PHARMACEUTICAL DESIGN (2017)
Targeted Delivery of CRISPR/Cas9-Mediated Cancer Gene Therapy via Liposome-Templated Hydrogel Nanoparticles
Zeming Chen et al.
ADVANCED FUNCTIONAL MATERIALS (2017)
Tumor cell-targeted delivery of CRISPR/Cas9 by aptamer-functionalized lipopolymer for therapeutic genome editing of VEGFA in osteosarcoma
Chao Liang et al.
BIOMATERIALS (2017)
Lipid nanoparticle-mediated efficient delivery of CRISPR/Cas9 for tumor therapy
Lingmin Zhang et al.
NPG ASIA MATERIALS (2017)
Porous Inorganic Drug Delivery Systems-a Review
E. Sayed et al.
AAPS PHARMSCITECH (2017)
Metal-Organic Framework (MOF)-Based Drug/Cargo Delivery and Cancer Therapy
Ming-Xue Wu et al.
ADVANCED MATERIALS (2017)
A Versatile Carbonic Anhydrase IX Targeting Ligand-Functionalized Porous Silicon Nanoplatform for Dual Hypoxia Cancer Therapy and Imaging
Agne Janoniene et al.
ACS APPLIED MATERIALS & INTERFACES (2017)
Stimuli-Responsive Polymersomes for Biomedical Applications
Xiuli Hu et al.
BIOMACROMOLECULES (2017)
Hyaluronic acid decorated pluronic P85 solid lipid nanoparticles as a potential carrier to overcome multidrug resistance in cervical and breast cancer
Fang Wang et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
Lung cancer combination therapy: co-delivery of paclitaxel and doxorubicin by nanostructured lipid carriers for synergistic effect
Yawei Wang et al.
DRUG DELIVERY (2016)
Polymeric Micelles: Recent Advancements in the Delivery of Anticancer Drugs
Avinash Gothwal et al.
PHARMACEUTICAL RESEARCH (2016)
pH-Sensitive ZnO Quantum Dots-Doxorubicin Nanoparticles for Lung Cancer Targeted Drug Delivery
Xiaoli Cai et al.
ACS APPLIED MATERIALS & INTERFACES (2016)
Extracellular vesicles for drug delivery
Pieter Vader et al.
ADVANCED DRUG DELIVERY REVIEWS (2016)
PEGylation as a strategy for improving nanoparticle-based drug and gene delivery
Jung Soo Suk et al.
ADVANCED DRUG DELIVERY REVIEWS (2016)
Ultrasensitive pH Triggered Charge/Size Dual-Rebound Gene Delivery System
Xiuwen Guan et al.
NANO LETTERS (2016)
Surface charge critically affects tumor penetration and therapeutic efficacy of cancer nanomedicines
Hong-Xia Wang et al.
NANO TODAY (2016)
EGCG/gelatin-doxorubicin gold nanoparticles enhance therapeutic efficacy of doxorubicin for prostate cancer treatment
Li-Chu Tsai et al.
NANOMEDICINE (2016)
Optimization of anti-cancer drugs and a targeting molecule on multifunctional gold nanoparticles
Nahla Rizk et al.
NANOTECHNOLOGY (2016)
Cdk5 disruption attenuates tumor PD-L1 expression and promotes antitumor immunity
R. Dixon Dorand et al.
SCIENCE (2016)
Targeting ABCB1 (MDR1) in multi-drug resistant osteosarcoma cells using the CRISPR-Cas9 system to reverse drug resistance
Tang Liu et al.
ONCOTARGET (2016)
Dual Receptor Recognizing Cell Penetrating Peptide for Selective Targeting, Efficient Intratumoral Diffusion and Synthesized Anti-Glioma Therapy
Yayuan Liu et al.
THERANOSTICS (2016)
Fabrication of dendrimer-releasing lipidic nanoassembly for cancer drug delivery
Qihang Sun et al.
BIOMATERIALS SCIENCE (2016)
Analysis of nanoparticle delivery to tumours
Stefan Wilhelm et al.
NATURE REVIEWS MATERIALS (2016)
Complete Regression of Xenograft Tumors upon Targeted Delivery of Paclitaxel via Π-Π Stacking Stabilized Polymeric Micelles
Yang Shi et al.
ACS NANO (2015)
Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing
Wujin Sun et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)
Bioapplications of hyperbranched polymers
Dali Wang et al.
CHEMICAL SOCIETY REVIEWS (2015)
Nanobody-based cancer therapy of solid tumors
Marta Kijanka et al.
NANOMEDICINE (2015)
Mesoporous silica nanoparticles in drug delivery and biomedical applications
Ying Wang et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2015)
Aptamers and Their Applications in Nanomedicine
Hongguang Sun et al.
SMALL (2015)
Anti-PEG immunity: emergence, characteristics, and unaddressed questions
Qi Yang et al.
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2015)
Advances and Challenges of Liposome Assisted Drug Delivery
Lisa Sercombe et al.
FRONTIERS IN PHARMACOLOGY (2015)
Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo
John A. Zuris et al.
NATURE BIOTECHNOLOGY (2015)
Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology
Nicolas Bertrand et al.
ADVANCED DRUG DELIVERY REVIEWS (2014)
In vitro and in vivo growth suppression of human papillomavirus 16-positive cervical cancer cells by CRISPR/Cas9
Shuai Zhen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Paclitaxel loaded liposomes decorated with a multifunctional tandem peptide for glioma targeting
Yayuan Liu et al.
BIOMATERIALS (2014)
Recent advances in non-ionic surfactant vesicles (niosomes): self-assembly, fabrication, characterization, drug delivery applications and limitations
Hamdy Abdelkader et al.
DRUG DELIVERY (2014)
Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA
Suresh Ramakrishna et al.
GENOME RESEARCH (2014)
Nano-niosomes as nanoscale drug delivery systems: An illustrated review
Saeid Moghassemi et al.
JOURNAL OF CONTROLLED RELEASE (2014)
Porous silicon nanoparticles for nanomedicine: preparation and biomedical applications
Helder A. Santos et al.
NANOMEDICINE (2014)
Targeted genome editing in human repopulating haematopoietic stem cells
Pietro Genovese et al.
NATURE (2014)
Self-assembled micellar nanocomplexes comprising green tea catechin derivatives and protein drugs for cancer therapy
Joo Eun Chung et al.
NATURE NANOTECHNOLOGY (2014)
Cationic Bovine Serum Albumin Based Self-Assembled Nanoparticles as siRNA Delivery Vector for Treating Lung Metastatic Cancer
Jianfeng Han et al.
SMALL (2014)
Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery
Steven Lin et al.
ELIFE (2014)
Bisphosphonate-Anchored PEGylation and Radiolabeling of Superparamagnetic Iron Oxide: Long-Circulating Nanoparticles for in Vivo Multimodal (T1 MRI-SPECT) Imaging
Lydia Sandiford et al.
ACS NANO (2013)
Functionalized, biodegradable hydrogels for control over sustained and localized siRNA delivery to incorporated and surrounding cells
Khanh Nguyen et al.
ACTA BIOMATERIALIA (2013)
Quantum dots as a platform for nanoparticle drug delivery vehicle design
Christine E. Probst et al.
ADVANCED DRUG DELIVERY REVIEWS (2013)
Folic Acid Modified Cationic γ-Cyclodextrin-oligoethylenimine Star Polymer with Bioreducible Disulfide Linker for Efficient Targeted Gene Delivery
Feng Zhao et al.
BIOMACROMOLECULES (2013)
Nanostructured lipid carriers as multifunctional nanomedicine platform for pulmonary co-delivery of anticancer drugs and siRNA
Oleh Taratula et al.
JOURNAL OF CONTROLLED RELEASE (2013)
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali et al.
SCIENCE (2013)
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong et al.
SCIENCE (2013)
Delivery of Small Interfering RNA by Peptide-Targeted Mesoporous Silica Nanoparticle-Supported Lipid Bilayers
Carlee E. Ashley et al.
ACS NANO (2012)
Lipid nanoparticles: state of the art, new preparation methods and challenges in drug delivery
Luigi Battaglia et al.
EXPERT OPINION ON DRUG DELIVERY (2012)
Laminin receptor specific therapeutic gold nanoparticles (198AuNP-EGCg) show efficacy in treating prostate cancer
Ravi Shukla et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jinek et al.
SCIENCE (2012)
Uniformity of Drug Payload and Its Effect on Stability of Solid Lipid Nanoparticles Containing an Ester Prodrug
Jin-Ki Kim et al.
ACS NANO (2011)
Multifunctional Triblock Nanocarrier (PAMAM-PEG-PLL) for the Efficient Intracellular siRNA Delivery and Gene Silencing
Mahesh L. Patil et al.
ACS NANO (2011)
Synthesis and Characterization of Carboxylic Acid Conjugated, Hydrophobically Derivatized, Hyperbranched Polyglycerols as Nanoparticulate Drug Carriers for Cisplatin
Lucy Ye et al.
BIOMACROMOLECULES (2011)
Formulation of Docetaxel by folic acid-conjugated D-α-tocopheryl polyethylene glycol succinate 2000 (Vitamin E TPGS2k) micelles for targeted and synergistic chemotherapy
Yu Mi et al.
BIOMATERIALS (2011)
pH-Sensitive degradable polymersomes for triggered release of anticancer drugs: A comparative study with micelles
Wei Chen et al.
JOURNAL OF CONTROLLED RELEASE (2010)
Endocytosis of nanomedicines
Gaurav Sahay et al.
JOURNAL OF CONTROLLED RELEASE (2010)
Self versus non-self discrimination during CRISPR RNA-directed immunity
Luciano A. Marraffini et al.
NATURE (2010)
Rational design of cationic lipids for siRNA delivery
Sean C. Semple et al.
NATURE BIOTECHNOLOGY (2010)
Tissue-Penetrating Delivery of Compounds and Nanoparticles into Tumors
Kazuki N. Sugahara et al.
CANCER CELL (2009)
An efficient cell-targeting and intracellular controlled-release drug delivery system based on MSN-PEM-aptamer conjugates
Chun-Ling Zhu et al.
JOURNAL OF MATERIALS CHEMISTRY (2009)
Diversity, activity, and evolution of CRISPR loci in Streptococcus thermophilus
Philippe Horvath et al.
JOURNAL OF BACTERIOLOGY (2008)
Phage response to CRISPR-Encoded resistance in Streptococcus thermophilus
Helene Deveau et al.
JOURNAL OF BACTERIOLOGY (2008)
Dendritic polyamine architectures with lipophilic shells as nanocompartments for polar guest molecules:: A comparative study of their transport behavior
M. Kraemer et al.
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY (2007)
CRISPR provides acquired resistance against viruses in prokaryotes
Rodolphe Barrangou et al.
SCIENCE (2007)
Cationic lipids, lipoplexes and intracellular delivery of genes
Luc Wasungu et al.
JOURNAL OF CONTROLLED RELEASE (2006)
Folate receptor-mediated drug targeting: From therapeutics to diagnostics
AR Hilgenbrink et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2005)
Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin
A Bolotin et al.
MICROBIOLOGY-SGM (2005)
Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements
FJM Mojica et al.
JOURNAL OF MOLECULAR EVOLUTION (2005)
RNA interference: Biology, mechanism, and applications
N Agrawal et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2003)
pRB2/p130 target genes in non-small lung cancer cells identified by microarray analysis
G Russo et al.
ONCOGENE (2003)
Pharmacokinetics of pegylated liposomal doxorubicin - Review of animal and human studies
A Gabizon et al.
CLINICAL PHARMACOKINETICS (2003)
Therapeutic cancer targeting peptides
OH Aina et al.
BIOPOLYMERS (2002)
Identification of genes that are associated with DNA repeats in prokaryotes
R Jansen et al.
MOLECULAR MICROBIOLOGY (2002)