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Intravitreal bevacizumab in active progressive proliferative diabetic retinopathy
Siamak Moradian et al.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY (2008)
Effect of candesartan on prevention (DIRECT-Prevent 1) and progression (DIRECT-Protect 1) of retinopathy in type 1 diabetes: randomised, placebo-controlled trials
Nish Chaturvedi et al.
LANCET (2008)
Cell-penetrating peptide for enhanced delivery of nucleic acids and drugs to ocular tissues including retina and cornea
Leslie N. Johnson et al.
MOLECULAR THERAPY (2008)
A randomized trial comparing intravitreal triamcinolone acetonide and focal/grid photocoagulation for diabetic macular edema
Michael S. Ip et al.
OPHTHALMOLOGY (2008)
Vitreous levels of bevackumab and vascular endothelial growth factor-A in patients with choroidal neovascularization
Qi Zhu et al.
OPHTHALMOLOGY (2008)
The Angio-Fibrotic Switch of VEGF and CTGF in Proliferative Diabetic Retinopathy
Esther J. Kuiper et al.
PLOS ONE (2008)
Tractional retinal detachment following intravitreal bevacizumab (Avastin) in patients with severe proliferative diabetic retinopathy
J. F. Arevalo et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2008)
Pharmacokinetics of intravitreal ranibizumab (Lucentis)
Sophie J. Bakri et al.
OPHTHALMOLOGY (2007)
Effect of VEGF-A on expression of profibrotic growth factor and extracellular matrix genes in the retina
Esther J. Kuiper et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2007)
Management of diabetic retinopathy - A systematic review
Quresh Mohamed et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2007)
Novel approaches to retinal drug delivery
Kumar G. Janoria et al.
EXPERT OPINION ON DRUG DELIVERY (2007)
Magnetic nanoparticles for drug delivery
Manuel Arruebo et al.
NANO TODAY (2007)
Pharmacokinetics of intravitreal bevackumab (avastin)
Sophie J. Bakri et al.
OPHTHALMOLOGY (2007)
Randomized controlled study of an intravitreous dexamethasone drug delivery system in patients with persistent macular edema
Baruch D. Kuppermann et al.
ARCHIVES OF OPHTHALMOLOGY (2007)
Topical administration of nepafenac inhibits diabetes-induced retinal microvascular disease and underlying abnormalities of retinal metabolism and physiology
Timothy S. Kern et al.
DIABETES (2007)
Arteriolar involvement in the microvascular lesions of diabetic retinopathy: Implications for pathogenesis
Tom A. Gardiner et al.
MICROCIRCULATION (2007)
Photodynamic therapy in subfoveal and juxtafoveal idiopathic and postinflammatory choroidal neovascularization
Jose M. Ruiz-Moreno et al.
ACTA OPHTHALMOLOGICA SCANDINAVICA (2006)
Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy
Prema Abraham et al.
OPHTHALMOLOGY (2006)
Intravitreal injection of bevacizumab (Avastin) as adjunctive treatment of proliferative diabetic retinopathy
John O. Mason et al.
AMERICAN JOURNAL OF OPHTHALMOLOGY (2006)
Association of connective tissue growth factor with fibrosis in vitreoretinal disorders in the human eye
Esther J. Kuiper et al.
ARCHIVES OF OPHTHALMOLOGY (2006)
Intravitreal bevacizumab (Avastin) in the treatment of proliferative diabetic retinopathy
Robert L. Avery et al.
OPHTHALMOLOGY (2006)
Intravitreal triamcinolone for refractory diabetic macular edema - Two-year results of a double-masked, placebo-controlled, randomized clinical trial
Mark C. Gillies et al.
OPHTHALMOLOGY (2006)
Pegaptanib as an adjunctive treatment for complicated neovascular diabetic retinopathy
MG Krzystolik et al.
ARCHIVES OF OPHTHALMOLOGY (2006)
Fluocinolone acetonide implant (Retisert) for noninfectious posterior uveitis - Thirty-four-week results of a multicenter randomized clinical study
GJ Jaffe et al.
OPHTHALMOLOGY (2006)
Chitosan nanoparticles as a potential drug delivery system for the ocular surface:: Toxicity, uptake mechanism and in vivo tolerance
AE de Salamanca et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)
Intravitreal bevacizumab (Avastin) treatment of proliferative diabetic retinopathy complicated by vitreous hemorrhage
Richard F. Spaide et al.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES (2006)
Hexosamines, insulin resistance, and the complications of diabetes: current status
MG Buse
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2006)
PKD at the crossroads of DAG and PKC signaling
Qiming J. Wang
TRENDS IN PHARMACOLOGICAL SCIENCES (2006)
Topical and systemic drug delivery to the posterior segments
PM Hughes et al.
ADVANCED DRUG DELIVERY REVIEWS (2005)
Increased sorbitol pathway activity generates oxidative stress in tissue sites for diabetic complications
IG Obrosova
ANTIOXIDANTS & REDOX SIGNALING (2005)
Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study):: randomised controlled trial
A Keech et al.
LANCET (2005)
Intravitreal injection versus sub-Tenon's infusion of triamcinolone acetonide for refractory diabetic macular edema: A randomized clinical trial
MA Bonini et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Topically applied antibody fragments penetrate into the back of the rabbit eye
KA Williams et al.
EYE (2005)
The pathobiology of diabetic complications - A unifying mechanism
M Brownlee
DIABETES (2005)
Intravitreal injection of corticosteroid attenuates leukostasis and vascular leakage in experimental diabetic retina
H Tamura et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Accumulation of NH2-terminal fragment of connective tissue growth factor in the vitreous of patients with proliferative diabetic retinopathy
DR Hinton et al.
DIABETES CARE (2004)
Connective tissue growth factor is up-regulated in the diabetic retina: Amelioration by angiotensin-converting enzyme inhibition
C Tikellis et al.
ENDOCRINOLOGY (2004)
Studies of rat and human retinas predict a role for the polyol pathway in human diabetic retinopathy
Z Dagher et al.
DIABETES (2004)
Pharmacokinetic-pharmacodynamic modeling of the effect of triamcinolone acetonide on central macular thickness in patients with diabetic macular edema
F Audren et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2004)
Simvastatin inhibits leukocyte accumulation and vascular permeability in the retinas of rats with streptozotocin-induced diabetes
S Miyahara et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Retinal angiogenesis is mediated by an interaction between the angiotensin type 2 receptor, VEGF, and angiopoietin
S Sarlos et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
Diabetic retinopathy and diabetic macular edema - Pathophysiology, screening, and novel therapies
TA Ciulla et al.
DIABETES CARE (2003)
Intraocular concentration and pharmacokinetics of triamcinolone acetonide after a single intravitreal injection
PM Beer et al.
OPHTHALMOLOGY (2003)
Subconjunctival nano- and microparticles sustain retinal delivery of budesonide, a corticosteroid capable of inhibiting VEGF expression
UB Kompella et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2003)
The renin-angiotensin system influences ocular endothelial cell proliferation in diabetes - Transgenic and interventional studies
CJ Moravski et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
Intraocular pressure after intravitreal injection of triamcinolone acetonide
JB Jonas et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2003)
Statins have biphasic effects on angiogenesis
M Weis et al.
CIRCULATION (2002)
Angiotensin converting enzyme inhibiting therapy is associated with lower vitreous vascular endothelial growth factor concentrations in patients with proliferative diabetic retinopathy
IMH van Buggenum et al.
DIABETOLOGIA (2002)
Angiotensin II and vascular endothelial growth factor in the vitreous fluid of patients with proliferative diabetic retinopathy
H Funatsu et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2002)
Biochemistry and molecular cell biology of diabetic complications
M Brownlee
NATURE (2001)
Connective tissue growth factor binds vascular endothelial growth factor (VEGF) and inhibits VEGF-induced angiogenesis
I Inoki et al.
FASEB JOURNAL (2001)
Excessive hexosamines block the neuroprotective effect of insulin and induce apoptosis in retinal neurons
M Nakamura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Octreotide reduces vitreous hemorrhage and loss of visual acuity risk in patients with high-risk proliferative diabetic retinopathy
BO Boehm et al.
HORMONE AND METABOLIC RESEARCH (2001)
Effect of particle size of polymeric nanospheres on intravitreal kinetics
E Sakurai et al.
OPHTHALMIC RESEARCH (2001)
Pharmacokinetics and safety of an anti-vascular endothelial growth factor aptamer (NX1838) following injection into the vitreous humor of rhesus monkeys
DW Drolet et al.
PHARMACEUTICAL RESEARCH (2000)
Angiotensin converting enzyme inhibition reduces retinal overexpression of vascular endothelial growth factor and hyperpermeability in experimental diabetes
RE Gilbert et al.
DIABETOLOGIA (2000)
Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation
XL Du et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
T Nishikawa et al.
NATURE (2000)
The efficacy of octreotide in the therapy of severe nonproliferative and early proliferative diabetic retinopathy - A randomized controlled study
MB Grant et al.
DIABETES CARE (2000)