4.5 Review

Metabolomics can provide new insights into perinatal nutrition

Journal

ACTA PAEDIATRICA
Volume 112, Issue 2, Pages 233-241

Publisher

WILEY
DOI: 10.1111/apa.16096

Keywords

breast milk; gestational diabetes; intrauterine growth restriction; metabolomics; perinatal nutrition

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Perinatal nutrition plays a crucial role in the developmental origins of health and disease. Metabolomics is a valuable tool for studying the impact of perinatal nutrition on both mothers and newborns. This review focuses on the main metabolites associated with gestational diabetes, intrauterine growth restriction, and breast milk.
Perinatal nutrition is a key factor related to the Developmental Origin of Health and Disease hypothesis, which states that each and every event that happens during the periconceptional period and pregnancy can affect the health status of an individual. Metabolomics can be a very useful tool for gathering information about the effect of perinatal nutrition on both mothers and newborn infants. This non-systematic review focuses on the main metabolites detected by this technique, with regard to gestational diabetes, intrauterine growth restriction and breast milk. Conclusion. Nutrition, metabolome and microbiome interactions are gaining interest in the scientific community.

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