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FDA drug approval summary: Pegaspargase (Oncaspar (R)) for the first-line treatment of children with acute lymphoblastic leukemia (ALL)
Patricia Anne Dinndorf et al.
ONCOLOGIST (2007)
Spleen plays an important role in the induction of accelerated blood clearance of PEGylated liposomes
Tatsuhiro Ishida et al.
JOURNAL OF CONTROLLED RELEASE (2006)
Accelerated blood clearance of PEGylated liposomes upon repeated injections: Effect of doxorubicin-encapsulation and high-dose first injection
Tatsuhiro Ishida et al.
JOURNAL OF CONTROLLED RELEASE (2006)
Injection of PEGylated liposomes in rats elicits PEG-specific IgM, which is responsible for rapid elimination of a second dose of PEGylated liposomes
T Ishida et al.
JOURNAL OF CONTROLLED RELEASE (2006)
Development of a highly active nanoliposomal irinotecan using a novel intraliposomal stabilization strategy
DC Drummond et al.
CANCER RESEARCH (2006)
Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease
EWM Ng et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Hypersensitivity and loss of disease site targeting caused by antibody responses to PEGylated liposomes
A Judge et al.
MOLECULAR THERAPY (2006)
Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase
NJ Ganson et al.
ARTHRITIS RESEARCH & THERAPY (2006)
PEGylation, successful approach to drug delivery
FM Veronese et al.
DRUG DISCOVERY TODAY (2005)
Safety assessment on polyethylene glycols (PEGs) and their derivatives as used in cosmetic products
C Fruijtier-Pölloth
TOXICOLOGY (2005)
Monoclonal antibody-based quantitation of poly(ethylene glycol-derivatized proteins, liposomes, and nanoparticles
TL Cheng et al.
BIOCONJUGATE CHEMISTRY (2005)
Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells
T Okada et al.
PLOS BIOLOGY (2005)
Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA
AD Judge et al.
NATURE BIOTECHNOLOGY (2005)
Immunogenicity and rapid blood clearance of liposomes containing polyethylene glycol-lipid conjugates and nucleic acid
SC Semple et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
TACI and BAFF-R mediate isotype switching in B cells
E Castigli et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Effect of the physicochemical properties of initially injected liposomes on the clearance of subsequently injected PEGylated liposomes in mice
T Ishida et al.
JOURNAL OF CONTROLLED RELEASE (2004)
Progress in modulating the RBC membrane to produce transfusable universal/stealth donor RBCs
G Garratty
TRANSFUSION MEDICINE REVIEWS (2004)
Immunogenicity of interferon beta: differences among products
A Bertolotto et al.
JOURNAL OF NEUROLOGY (2004)
Environmental and genetic factors influencing inhibitor development
J Oldenburg et al.
SEMINARS IN HEMATOLOGY (2004)
Complement activation following first exposure to pegylated liposomal doxorubicin (Doxil): possible role in hypersensitivity reactions
A Chanan-Khan et al.
ANNALS OF ONCOLOGY (2003)
Immunogenicity of therapeutic proteins: Clinical implications and future prospects
H Schellekens
CLINICAL THERAPEUTICS (2002)
DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL
MB Litinskiy et al.
NATURE IMMUNOLOGY (2002)
Bioequivalence and the immunogenicity of biopharmaceuticals
H Schellekens
NATURE REVIEWS DRUG DISCOVERY (2002)
Synthesis and release of B-lymphocyte stimulator from myeloid cells
B Nardelli et al.
BLOOD (2001)
Pharmacokinetics and safety of an anti-vascular endothelial growth factor aptamer (NX1838) following injection into the vitreous humor of rhesus monkeys
DW Drolet et al.
PHARMACEUTICAL RESEARCH (2000)
Pegylated interferon-α2b:: Pharmacokinetics, pharmacodynamics, safety, and preliminary efficacy data
P Glue et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2000)
Doxorubicin entrapped within liposome-associated antigens results in a selective inhibition of the antibody response to the linked antigen
C Oja et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2000)
Comparison of in vitro antibody-targeted cytotoxicity using mouse, rat and human effectors
I Bergman et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2000)
Efficient clearance of poly(ethylene glycol)modified immunoenzyme with anti-PEG monoclonal antibody for prodrug cancer therapy
TL Cheng et al.
BIOCONJUGATE CHEMISTRY (2000)
B cells extract and present immobilized antigen: implications for affinity discrimination
FD Batista et al.
EMBO JOURNAL (2000)