4.6 Article

Rapid Generation of Neurospheres from Hippocampal Neurons Using Extracellular-Matrix-Mimetic Scaffolds

Related references

Note: Only part of the references are listed.
Article Materials Science, Biomaterials

Impact of the physico-chemical properties of polymeric microspheres functionalized with cell adhesion molecules on the behavior of mesenchymal stromal cells

Assia Rmaidi et al.

Summary: This study aimed to characterize the physicochemical properties of two polymeric microsphere (MS) systems and evaluate the effect of laminin and poly-n-lysine coatings on stem cell behavior. The results showed that PLGA microspheres promoted protein adsorption and cell adhesion, while PLGA-P188-PLGA microspheres had less protein adsorption and resulted in round cell morphology. However, the long-term cell behavior, including cell number, differentiation profile, and ECM secretion, were not significantly influenced by the type of microcarrier used. The study suggests that the ECM molecules surrounding the microcarrier/cell constructs play a role in converging cell behavior over time.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2021)

Article Chemistry, Multidisciplinary

ECM-Mimetic Nylon Nanofiber Scaffolds for Neurite Growth Guidance

Olga Y. Antonova et al.

Summary: Nanostructured synthetic scaffolds mimicking the natural extracellular matrix have been studied, with ultra-thin nylon-4,6 nanofibers showing enhanced efficiency in promoting neuron growth compared to thicker nanofibers. Both types of scaffolds improved synaptogenesis and cell connections, though with different mechanisms of interaction. The findings demonstrate the potential of ultra-thin nanofiber scaffolds for clinical applications in nervous tissue regeneration.

NANOMATERIALS (2021)

Review Biotechnology & Applied Microbiology

Electrospun Fiber Scaffolds for Engineering Glial Cell Behavior to Promote Neural Regeneration

Devan L. Puhl et al.

Summary: Electrospun fiber scaffolds mimic the structure of the nervous system extracellular matrix and provide contact guidance for regenerating axons. Glial cells respond differently to fiber alignment, diameter, surface nanotopography, and surface chemistry, offering potential for design and optimization of electrospun fiber scaffolds to target glial cell response in nerve injury and regeneration. Additionally, electrospun fibers can be loaded with therapeutics for local, sustained release to alter glial cell phenotype and support regeneration.

BIOENGINEERING-BASEL (2021)

Article Cell Biology

Tsukushi is essential for proper maintenance and terminal differentiation of mouse hippocampal neural stem cells

Shah Adil Ishtiyaq Ahmad et al.

DEVELOPMENT GROWTH & DIFFERENTIATION (2020)

Article Cell Biology

A brief history of organoids

Claudia Corro et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2020)

Review Biochemistry & Molecular Biology

3D Extracellular Matrix Mimics: Fundamental Concepts and Role of Materials Chemistry to Influence Stem Cell Fate

Julien Nicolas et al.

BIOMACROMOLECULES (2020)

Review Cell Biology

Mechanical Regulation of Nuclear Translocation in Migratory Neurons

Naotaka Nakazawa et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

Review Chemistry, Multidisciplinary

Maneuvering the Migration and Differentiation of Stem Cells with Electrospun Nanofibers

Jiajia Xue et al.

ADVANCED SCIENCE (2020)

Review Cell Biology

Forces to Drive Neuronal Migration Steps

Takunori Minegishi et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

Review Cell Biology

The Application of Brain Organoids: From Neuronal Development to Neurological Diseases

Yikai Shou et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)

Article Multidisciplinary Sciences

ECM-inspired micro/nanofibers for modulating cell function and tissue generation

Yun Xu et al.

SCIENCE ADVANCES (2020)

Article Cell & Tissue Engineering

3D brain tissue physiological model with co-cultured primary neurons and glial cells in hydrogels

Ilaria Raimondi et al.

JOURNAL OF TISSUE ENGINEERING (2020)

Review Developmental Biology

Brain organoids: advances, applications and challenges

Xuyu Qian et al.

DEVELOPMENT (2019)

Article Multidisciplinary Sciences

Generation of Neurospheres from Mixed Primary Hippocampal and Cortical Neurons Isolated from E14-E16 Sprague Dawley Rat Embryo

Gaurav Das et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2019)

Review Biotechnology & Applied Microbiology

Neural Lineage Differentiation From Pluripotent Stem Cells to Mimic Human Brain Tissues

Yean Ju Hong et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2019)

Article Nanoscience & Nanotechnology

The Effect of Electrospun Fiber Diameter on Astrocyte-Mediated Neurite Guidance and Protection

Christopher D. L. Johnson et al.

ACS APPLIED BIO MATERIALS (2019)

Article Medicine, Research & Experimental

Interaction of iPSC-derived neural stem cells on poly(L-lactic acid) nanofibrous scaffolds for possible use in neural tissue engineering

Chengkai Lin et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2018)

Article Cell Biology

Stem cell models of human synapse development and degeneration

Emily S. Wilson et al.

MOLECULAR BIOLOGY OF THE CELL (2018)

Article Nanoscience & Nanotechnology

Perspective: Aligned arrays of electrospun nanofibers for directing cell migration

Jiajia Xue et al.

APL MATERIALS (2018)

Article Medicine, General & Internal

β1 integrin signaling promotes neuronal migration along vascular scaffolds in the post-stroke brain

Teppei Fujioka et al.

EBIOMEDICINE (2017)

Article Polymer Science

Filtering and optical properties of free standing electrospun nanomats from nylon-4,6

Andrei Y. Mikheev et al.

EUROPEAN POLYMER JOURNAL (2016)

Article Neurosciences

Surface Topography During Neural Stem Cell Differentiation Regulates Cell Migration and Cell Morphology

Catherine Czeisler et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2016)

Article Multidisciplinary Sciences

Generation and transplantation of reprogrammed human neurons in the brain using 3D microtopographic scaffolds

Aaron L. Carlson et al.

NATURE COMMUNICATIONS (2016)

Article Cell Biology

Regulation of astrocyte activity via control over stiffness of cellulose acetate electrospun nanofiber

Seul Ki Min et al.

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL (2015)

Article Biochemical Research Methods

Quantitative and unbiased analysis of directional persistence in cell migration

Roman Gorelik et al.

NATURE PROTOCOLS (2014)

Article Multidisciplinary Sciences

Step-by-step quantitative analysis of focal adhesions

Utku Horzum et al.

METHODSX (2014)

Review Cell Biology

Mechanisms of cell migration in the nervous system

Jonathan A. Cooper

JOURNAL OF CELL BIOLOGY (2013)

Article Cell & Tissue Engineering

Nanofibrous Collagen Nerve Conduits for Spinal Cord Repair

Ting Liu et al.

TISSUE ENGINEERING PART A (2012)

Article Polymer Science

The Tensile Properties of Electrospun Nylon 6 Single Nanofibers

Mohamed Basel Bazbouz et al.

JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS (2010)

Article Chemistry, Multidisciplinary

Continuous electrospinning of aligned polymer nanofibers onto a wire drum collector

P Katta et al.

NANO LETTERS (2004)