4.6 Review

Bromelain a Potential Bioactive Compound: A Comprehensive Overview from a Pharmacological Perspective

Journal

LIFE-BASEL
Volume 11, Issue 4, Pages -

Publisher

MDPI
DOI: 10.3390/life11040317

Keywords

bromelain; Ananas comosus; pineapple; nanoparticles; proteolytic enzymes

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Bromelain, derived from pineapple stems, is an effective proteolytic enzyme commonly used as an anti-inflammatory agent. It has shown potential for anticancer and antimicrobial properties, and positive effects on various systems, especially in arthritis relief. Research suggests its low toxicity and relationship with nanoparticles, urging further exploration for its diverse healthcare applications.
Bromelain is an effective chemoresponsive proteolytic enzyme derived from pineapple stems. It contains several thiol endopeptidases and is extracted and purified via several methods. It is most commonly used as an anti-inflammatory agent, though scientists have also discovered its potential as an anticancer and antimicrobial agent. It has been reported as having positive effects on the respiratory, digestive, and circulatory systems, and potentially on the immune system. It is a natural remedy for easing arthritis symptoms, including joint pain and stiffness. This review details bromelain's varied uses in healthcare, its low toxicity, and its relationship to nanoparticles. The door of infinite possibilities will be opened up if further extensive research is carried out on this pineapple-derived enzyme.

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