Related references
Note: Only part of the references are listed.The Pharmaceutical Industry in 2020. An Analysis of FDA Drug Approvals from the Perspective of Molecules
Beatriz G. de la Torre et al.
MOLECULES (2021)
Diet aid or aid to die: an update on 2,4-dinitrophenol (2,4-DNP) use as a weight-loss product
Daniela Sousa et al.
ARCHIVES OF TOXICOLOGY (2020)
Anilinopyrazines as potential mitochondrial uncouplers
Jacob H. Murray et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2020)
Artepillin C, a Key Component of Brazilian Propolis, Induces Thermogenesis in Inguinal White Adipose Tissue of Mice through a Creatine-Metabolism-Related Thermogenic Pathway
Sho Nishikawa et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2020)
Beta-1 and Not Beta-3 Adrenergic Receptors May Be the Primary Regulator of Human Brown Adipocyte Metabolism
Mette Ji Riis-Vestergaard et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2020)
Testing for GW501516 (cardarine) in human hair using LC/MS-MS and confirmation by LC/HRMS
Pascal Kintz et al.
DRUG TESTING AND ANALYSIS (2020)
The β3-adrenergic receptor agonist mirabegron improves glucose homeostasis in obese humans
Brian S. Finlin et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
Anabolic androgenic steroid abuse in young males
Willem de Ronde et al.
ENDOCRINE CONNECTIONS (2020)
No effect of resveratrol supplementation after 6 months on insulin sensitivity in overweight adults: a randomized trial
Marlies de Ligt et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2020)
Individuals with obesity and COVID-19: A global perspective on the epidemiology and biological relationships
Barry M. Popkin et al.
OBESITY REVIEWS (2020)
Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials
Karine Clement et al.
LANCET DIABETES & ENDOCRINOLOGY (2020)
Acute metabolic and cardiovascular effects of mirabegron in healthy individuals
Rebecca K. C. Loh et al.
DIABETES OBESITY & METABOLISM (2019)
Treatment with celastrol protects against obesity through suppression of galanin-induced fat intake and activation of PGC-1a/GLUT4 axis-mediated glucose consumption
Penghua Fang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2019)
Role of PPAR receptor in different diseases and their ligands: Physiological importance and clinical implications
Agha Zeeshan Mirza et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Hypothalamic Obesity: Prologue and Promise
M. Jennifer Abuzzahab et al.
HORMONE RESEARCH IN PAEDIATRICS (2019)
Obesity: global epidemiology and pathogenesis
Matthias Blueher
NATURE REVIEWS ENDOCRINOLOGY (2019)
EPA and DHA elicit distinct transcriptional responses to high-fat feeding in skeletal muscle and liver
Hawley E. Kunz et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2019)
Role of metformin in overweight and obese people without diabetes: a systematic review and network meta-analysis
Fuhai Hui et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2019)
Fish Oil Protects Wild Type and Uncoupling Protein 1-Deficient Mice from Obesity and Glucose Intolerance by Increasing Energy Expenditure
Tiago E. Oliveira et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2019)
The leptin sensitizer celastrol reduces age-associated obesity and modulates behavioral rhythms
Karthikeyani Chellappa et al.
AGING CELL (2019)
Thyroid hormone metabolites and analogues
Rosalba Senese et al.
ENDOCRINE (2019)
Metformin: Mechanisms in Human Obesity and Weight Loss
Armen Yerevanian et al.
CURRENT OBESITY REPORTS (2019)
Small Molecule Mitochondrial Uncouplers and Their Therapeutic Potential
Elizabeth S. Childress et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Targeting thermogenesis in brown fat and muscle to treat obesity and metabolic disease
Matthias J. Betz et al.
NATURE REVIEWS ENDOCRINOLOGY (2018)
Central regulation of brown adipose tissue thermogenesis and energy homeostasis dependent on food availability
Yoshiko Nakamura et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2018)
Treatment with Growth Hormone for Adults with Growth Hormone Deficiency Syndrome: Benefits and Risks
Juan J. Diez et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
INT-767 prevents NASH and promotes visceral fat brown adipogenesis and mitochondrial function
Paolo Comeglio et al.
JOURNAL OF ENDOCRINOLOGY (2018)
Effects of recombinant human growth hormone administration on cardiovascular risk factors in obese children with relative growth hormone deficiency
Shuang Liang et al.
LIPIDS IN HEALTH AND DISEASE (2018)
MC4R Agonists: Structural Overview on Antiobesity Therapeutics
Juliana Pereira Lopes Goncalves et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2018)
Sarcolipin Signaling Promotes Mitochondrial Biogenesis and Oxidative Metabolism in Skeletal Muscle
Santosh K. Maurya et al.
CELL REPORTS (2018)
Gamma-Aminobutyric Acid Signaling in Brown Adipose Tissue Promotes Systemic Metabolic Derangement in Obesity
Ryutaro Ikegami et al.
CELL REPORTS (2018)
The Role of Sarcolipin in Muscle Non-shivering Thermogenesis
Naresh C. Bal et al.
FRONTIERS IN PHYSIOLOGY (2018)
Safety assessment of combination therapies in the treatment of obesity: focus on naltrexone/bupropion extended release and phentermine-topiramate extended release
Bruno Halpern et al.
EXPERT OPINION ON DRUG SAFETY (2017)
The influence of AICAR - direct activator of AMP-activated protein kinase (AMPK) - on liver proteome in apoE-knockout mice
Maciej Suski et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2017)
Protective effects of various ratios of DHA/EPA supplementation on high-fat diet-induced liver damage in mice
Tingting Shang et al.
LIPIDS IN HEALTH AND DISEASE (2017)
Human brown adipose tissue as a target for obesity management; beyond cold-induced thermogenesis
R. K. C. Loh et al.
OBESITY REVIEWS (2017)
Caffeine inhibits hypothalamic A1R to excite oxytocin neuron and ameliorate dietary obesity in mice
Liufeng Wu et al.
NATURE COMMUNICATIONS (2017)
Beneficial effects of metformin on energy metabolism and visceral fat volume through a possible mechanism of fatty acid oxidation in human subjects and rats
Ichiro Tokubuchi et al.
PLOS ONE (2017)
Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia
Marcela Doktorova et al.
SCIENTIFIC REPORTS (2017)
The mechanisms of action of metformin
Graham Rena et al.
DIABETOLOGIA (2017)
Roles of Peroxisome Proliferator-Activated Receptor β/δ in skeletal muscle physiology
Ravikumar Manickam et al.
BIOCHIMIE (2017)
Sobetirome: the past, present and questions about the future
Jan Lammel Lindemann et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2016)
Bile acid receptor agonists. INT747 and INT777 decrease oestrogen deficiency-related postmenopausal obesity and hepatic steatosis in mice
Monique C. de Oliveira et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2016)
Magel2-null mice are hyper-responsive to setmelanotide, a melanocortin 4 receptor agonist
Jocelyn M. Bischof et al.
BRITISH JOURNAL OF PHARMACOLOGY (2016)
Renaissance of leptin for obesity therapy
Carmelo Quarta et al.
DIABETOLOGIA (2016)
Stress, cortisol, and obesity: a role for cortisol responsiveness in identifying individuals prone to obesity
S. D. Hewagalamulage et al.
DOMESTIC ANIMAL ENDOCRINOLOGY (2016)
Beta3-adrenoreceptor agonist mirabegron - a potential antiobesity drug?
Vojtech Hainer
EXPERT OPINION ON PHARMACOTHERAPY (2016)
Activation of Transmembrane Bile Acid Receptor TGR5 Modulates Pancreatic Islet Cells to Promote Glucose Homeostasis
Divya P. Kumar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Nuclear receptors and AMPK: can exercise mimetics cure diabetes?
Christopher E. Wall et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2016)
Anti-obesity effects of resveratrol: comparison between animal models and humans
Alfredo Fernandez-Quintela et al.
JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY (2016)
Artepillin C, a Typical Brazilian Propolis-Derived Component, Induces Brown-Like Adipocyte Formation in C3H10T1/2 Cells, Primary Inguinal White Adipose Tissue-Derived Adipocytes, and Mice
Sho Nishikawa et al.
PLOS ONE (2016)
Effect of DHA supplementation in a very low-calorie ketogenic diet in the treatment of obesity: a randomized clinical trial
Daniel de Luis et al.
ENDOCRINE (2016)
Resveratrol and obesity: Can resveratrol relieve metabolic disturbances?
Marlies de Ligt et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2015)
Brazilian propolis extract increases leptin expression in mouse adipocytes
Kohei Washio et al.
BIOMEDICAL RESEARCH-TOKYO (2015)
Treatment of Obesity with Celastrol
Junli Liu et al.
CELL (2015)
A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat
Lawrence Kazak et al.
CELL (2015)
Activation of Human Brown Adipose Tissue by a β3-Adrenergic Receptor Agonist
Aaron M. Cypess et al.
CELL METABOLISM (2015)
Chronic ephedrine administration decreases brown adipose tissue activity in a randomised controlled human trial: implications for obesity
Andrew L. Carey et al.
DIABETOLOGIA (2015)
Combination phentermine and topiramate extended release in the management of obesity
Nasreen Alfaris et al.
EXPERT OPINION ON PHARMACOTHERAPY (2015)
Sarcolipin Is a Key Determinant of the Basal Metabolic Rate, and Its Overexpression Enhances Energy Expenditure and Resistance against Diet-induced Obesity
Santosh K. Maurya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
RM-493, a Melanocortin-4 Receptor (MC4R) Agonist, Increases Resting Energy Expenditure in Obese Individuals
Kong Y. Chen et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2015)
Early controlled release of peroxisome proliferator-activated receptor β/δ agonist GW501516 improves diabetic wound healing through redox modulation of wound microenvironment
Xiaoling Wang et al.
JOURNAL OF CONTROLLED RELEASE (2015)
Leptin resistance and diet-induced obesity: central and peripheral actions of leptin
Neira Sainz et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2015)
The Chemical Uncoupler 2,4-Dinitrophenol (DNP) Protects against Diet-induced Obesity and Improves Energy Homeostasis in Mice at Thermoneutrality
Margalit Goldgof et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Peroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications - a review
Bogna Grygiel-Gorniak
NUTRITION JOURNAL (2014)
A novel chemical uncoupler ameliorates obesity and related phenotypes in mice with diet-induced obesity by modulating energy expenditure and food intake
Y. -Y. Fu et al.
DIABETOLOGIA (2013)
Obesity pharmacotherapy: What is next?
Francheska Colon-Gonzalez et al.
MOLECULAR ASPECTS OF MEDICINE (2013)
Lipid Effects of Peroxisome Proliferator-Activated Receptor-δ Agonist GW501516 in Subjects With Low High-Density Lipoprotein Cholesterol Characteristics of Metabolic Syndrome
Eric J. Olson et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2012)
Cellular and molecular mechanisms of metformin: an overview
Benoit Viollet et al.
CLINICAL SCIENCE (2012)
Discovery of a Potent, Selective, and Orally Bioavailable Acidic 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Inhibitor: Discovery of 2-[(3S)-1[5-(Cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl]-3-piperidyl]acetic Acid (AZD4017)
James S. Scott et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Metformin Inhibits Nuclear Receptor TR4-Mediated Hepatic Stearoyl-CoA Desaturase 1 Gene Expression With Altered Insulin Sensitivity
Eungseok Kim et al.
DIABETES (2011)
AICAR, an activator of AMPK, inhibits adipogenesis via the WNT/β-catenin pathway in 3T3-L1 adipocytes
Haeyong Lee et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2011)
Chronic AMP-kinase activation with AICAR reduces adiposity by remodeling adipocyte metabolism and increasing leptin sensitivity
Mandeep P. Gaidhu et al.
JOURNAL OF LIPID RESEARCH (2011)
Leptin Action in the Dorsomedial Hypothalamus Increases Sympathetic Tone to Brown Adipose Tissue in Spite of Systemic Leptin Resistance
Pablo J. Enriori et al.
JOURNAL OF NEUROSCIENCE (2011)
2,4-Dinitrophenol (DNP): A Weight Loss Agent with Significant Acute Toxicity and Risk of Death
Johann Grundlingh et al.
JOURNAL OF MEDICAL TOXICOLOGY (2011)
The 11-β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor INCB13739 Improves Hyperglycemia in Patients With Type 2 Diabetes Inadequately Controlled by Metformin Monotherapy
Julio Rosenstock et al.
DIABETES CARE (2010)
11 beta-Hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of type 2 diabetes
Stuart A. Morgan et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2010)
Cellular bioenergetics as a target for obesity therapy
Yu-Hua Tseng et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis
Charles Thomas et al.
CELL METABOLISM (2009)
Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation
Philippe Lefebvre et al.
PHYSIOLOGICAL REVIEWS (2009)
The efficiency of cellular energy transduction and its implications for obesity
Mary-Ellen Harper et al.
ANNUAL REVIEW OF NUTRITION (2008)
Activation of peroxisome proliferator-activated receptor (PPAR)δ promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatly acid oxidation in moderately obese men
Ulf Riserus et al.
DIABETES (2008)
Targeting thyroid hormone receptor-β agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index
Mark D. Erion et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Thyroid hormone receptor β-specific agonist GC-1 increases energy expenditure and prevents fat-mass accumulation in rats
Cassio M. Villicev et al.
JOURNAL OF ENDOCRINOLOGY (2007)
Long-term weight loss maintenance
RR Wing et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2005)
11β-hydroxysteroid dehydrogenase type 1 activity in lean and obese males with type 2 diabetes mellitus
G Valsamakis et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
KT Howitz et al.
NATURE (2003)
Selective thyroid hormone receptor-β activation:: A strategy for reduction of weight, cholesterol, and lipoprotein (a) with reduced cardiovascular liability
GJ Grover et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
A 6-month randomized, placebo-controlled, dose-ranging trial of topiramate for weight loss in obesity
GA Bray et al.
OBESITY RESEARCH (2003)
The function of the nuclear receptor perokisome proliferator-activated receptor delta in energy horneostasis
G Wolf
NUTRITION REVIEWS (2003)
Effect of a 28-d treatment with L-796568, a novel β3-adrenergic receptor agonist, on energy expenditure and body composition in obese men
TM Larsen et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2002)
Acute effect of L-796568, a novel β3-adrenergic receptor agonist, on energy expenditure in obese men
MA van Baak et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2002)
Topiramate as an inhibitor of carbonic anhydrase isoenzymes
SJ Dodgson et al.
EPILEPSIA (2000)
Share Paper
