4.6 Review

Therapeutic Strategies for Metastatic Triple-Negative Breast Cancers: From Negative to Positive

Related references

Note: Only part of the references are listed.
Editorial Material Medicine, General & Internal

Adjuvant Capecitabine in Triple-Negative Breast Cancer New Strategies for Tailoring Treatment Recommendations

Heather A. Parsons et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

Article Medicine, General & Internal

Effect of Capecitabine Maintenance Therapy Using Lower Dosage and Higher Frequency vs Observation on Disease-Free Survival Among Patients With Early-Stage Triple-Negative Breast Cancer Who Had Received Standard Treatment The SYSUCC-001 Randomized Clinical Trial

Xi Wang et al.

Summary: This study aimed to evaluate the efficacy and adverse effects of low-dose capecitabine maintenance therapy after standard adjuvant chemotherapy in early-stage triple-negative breast cancer. The results showed significantly improved 5-year disease-free survival in patients receiving capecitabine treatment.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

Article Oncology

A novel humanized Frizzled-7-targeting antibody enhances antitumor effects of Bevacizumab against triple-negative breast cancer via blocking Wnt/β-catenin signaling pathway

Wei Xie et al.

Summary: A novel humanized antibody targeting Fzd7, named SHH002-hu1, was developed and demonstrated potential anti-tumor activity. It showed high affinity with Fzd7, specifically targeted Fzd7(+) cells and tumor tissues, and enhanced the anti-TNBC capacity of Bevacizumab through inhibiting Wnt/beta-catenin signaling. SHH002-hu1 could be a promising candidate for synergistic therapy with Bevacizumab in preventing TNBC recurrence.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2021)

Article Oncology

Mutated p53 portends improvement in outcomes when bevacizumab is combined with chemotherapy in advanced/recurrent endometrial cancer: An NRG Oncology study

Kimberly K. Leslie et al.

Summary: The study suggests that mutations in the TP53 gene are associated with improved progression-free survival (PFS) and overall survival (OS) in advanced endometrial cancer patients receiving bevacizumab, compared to temsirolimus. This indicates that TP53 mutational status may serve as a potential biomarker for guiding treatment choices in endometrial cancer patients.

GYNECOLOGIC ONCOLOGY (2021)

Editorial Material Medicine, General & Internal

Precision Dosing A Clinical and Public Health Imperative

Kimberly Maxfield et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

Review Oncology

Emerging role of PTEN loss in evasion of the immune response to tumours

Thiago Vidotto et al.

BRITISH JOURNAL OF CANCER (2020)

Review Oncology

Triple-negative breast cancer therapy: Current and future perspectives (Review)

Kwang-Ai Won et al.

INTERNATIONAL JOURNAL OF ONCOLOGY (2020)

Article Medicine, General & Internal

Sacituzumab Govitecan-hziy in Refractory Metastatic Triple-Negative Breast Cancer

A. Bardia et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Biochemistry & Molecular Biology

Molecular profiling of cancer patients enables personalized combination therapy: the I-PREDICT study

Jason K. Sicklick et al.

NATURE MEDICINE (2019)

Article Medicine, General & Internal

Alpelisib for PIK3CA-Mutated, Hormone Receptor-Positive Advanced Breast Cancer

Fabrice Andre et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Oncology

Enzalutamide for the Treatment of Androgen Receptor-Expressing Triple-Negative Breast Cancer

Tiffany A. Traina et al.

JOURNAL OF CLINICAL ONCOLOGY (2018)

Article Medicine, General & Internal

Talazoparib in Patients with Advanced Breast Cancer and a Germline BRCA Mutation

Jennifer K. Litton et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Medicine, General & Internal

Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer

P. Schmid et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Medicine, General & Internal

Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation

Mark Robson et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Oncology

Selective activity of deguelin identifies therapeutic targets for androgen receptor-positive breast cancer

Andrew J. Robles et al.

BREAST CANCER RESEARCH AND TREATMENT (2016)

Review Oncology

Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease

Giampaolo Bianchini et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2016)

Article Biochemistry & Molecular Biology

The PARP1 inhibitor BMN 673 exhibits immunoregulatory effects in a Brca1-/- murine model of ovarian cancer

Jing Huang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)

Review Pharmacology & Pharmacy

Targeting the Wnt pathway in human cancers: Therapeutic targeting with a focus on OMP-54F28

Phuong N. Le et al.

PHARMACOLOGY & THERAPEUTICS (2015)

Review Pharmacology & Pharmacy

Targeting Basal-Like Breast Cancers

Nandini Dey et al.

CURRENT DRUG TARGETS (2012)

Article Multidisciplinary Sciences

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

Sohrab P. Shah et al.

NATURE (2012)

Article Multidisciplinary Sciences

Comprehensive molecular portraits of human breast tumours

Daniel C. Koboldt et al.

NATURE (2012)

Article Oncology

Antibody Conjugate Therapeutics: Challenges and Potential

Beverly A. Teicher et al.

CLINICAL CANCER RESEARCH (2011)

Article Medicine, Research & Experimental

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

Brian D. Lehmann et al.

JOURNAL OF CLINICAL INVESTIGATION (2011)

Article Oncology

Triple-Negative Breast Cancers: Unique Clinical Presentations and Outcomes

Julie A. Y. Billar et al.

ANNALS OF SURGICAL ONCOLOGY (2010)

Review Medicine, General & Internal

Triple-Negative Breast Cancer

William D. Foulkes et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Medicine, General & Internal

Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers.

Peter C. Fong et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Multidisciplinary Sciences

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

H Farmer et al.

NATURE (2005)

Article Multidisciplinary Sciences

Role of histone H3 lysine 27 methylation in polycomb-group silencing

R Cao et al.

SCIENCE (2002)