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FEBS JOURNAL (2009)
Gene mutations and response to treatment with all-trans retinoic acid in elderly patients with acute myeloid leukemia. Results from the AMLSG Trial AML HD98B
Richard F. Schlenk et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2009)
Apolipoprotein CIII Links Dyslipidemia with Atherosclerosis
Akio Kawakami et al.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS (2009)
A subset of patients with high-risk acute myelogenous leukemia shows improved peripheral blood cell counts when treated with the combination of valproic acid, theophylline and all-trans retinoic acid
Anita Ryningen et al.
LEUKEMIA RESEARCH (2009)
ASH evidence-based guidelines: is there a role for second allogeneic transplant after relapse?
M. S. Thakar et al.
Hematology-American Society of Hematology Education Program (2009)
High EVI1 levels predict adverse outcome in acute myeloid leukemia:: prevalence of EVI1 overexpression. and chromosome 3q26 abnormalities underestimated
Sanne Lugthart et al.
BLOOD (2008)
In vivo biological effects of ATRA in the treatment of AML
Anita Ryningen et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2008)
Expression and prognostic significance of different mRNA 5 ' - End variants of the oncogene EVII in 266 patients with de novo AML: EVII and MDSI/EVII overexpression both predict short remission duration
Katja Haas et al.
GENES CHROMOSOMES & CANCER (2008)
Impact of different post-remission strategies on quality of life in patients with acute myeloid leukemia
Doyle Messerer et al.
HAEMATOLOGICA (2008)
Deacetylase inhibition promotes the generation and function of regulatory T cells
Ran Tao et al.
NATURE MEDICINE (2007)
Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia
William Blum et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
MNI overexpression induces acute myeloid leukemia in mice and predicts ATRA resistance in patients with AML
Michael Heuser et al.
BLOOD (2007)
Histone deacetylase inhibitors affect dendritic cell differentiation and immunogenicity
Alessio Nencioni et al.
CLINICAL CANCER RESEARCH (2007)
Targeting AML1/ETO-histone deacetylase repressor complex: A novel mechanism for valproic acid-mediated gene expression and cellular differentiation in AML1/ETO-positive acute myeloid leukemia cells
Shujun Liu et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia
Francesco Fazi et al.
BLOOD (2007)
Effect of histone deacetylase inhibitor valproic acid on progenitor cells of acute myeloid leukemia
Gesine Bug et al.
HAEMATOLOGICA (2007)
Histone deacetylase inhibitors in cancer treatment:: A review of the clinical toxicity and the modulation of gene expression in cancer cells
O. Bruserud et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2007)
Valproic acid malignancies for the treatment of myeloid
Andrea Kuendgen et al.
CANCER (2007)
Phase 1/2 study of the combination of 5-aza-2′-deoxycytidine with valproic acid in patients with leukemia
Guillermo Garcia-Manero et al.
BLOOD (2006)
Sequential valproic acid/all-trans retinoic acid treatment reprograms differentiation in refractory and high-risk acute myeloid leukemia
Giuseppe Cimino et al.
CANCER RESEARCH (2006)
A phase I study of intravenous LBH589, a novel cinnamic hydroxamic acid analogue histone deacetylase inhibitor, in patients with refractory hematologic malignancies
Francis Giles et al.
CLINICAL CANCER RESEARCH (2006)
Btg2 enhances retinoic acid-induced differentiation by modulating histone H4 methylation and acetylation
Daniela Passeri et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Synergistic induction of folate receptor β by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells:: Mechanism and utility in enhancing selective growth inhibition by antifolates
Huiling Qi et al.
CANCER RESEARCH (2006)
Histone deacetylases as targets for dietary cancer preventive agents: Lessons learned with butyrate, diallyl disulfide, and sulforaphane
MC Myzak et al.
CURRENT DRUG TARGETS (2006)
The histone deacetylase (HDAC) inhibitor valproic acid as monotherapy or in combination moth all-trans retinoic acid in patients with acute myeloid leukemia
A Kuendgen et al.
CANCER (2006)
Clinical trial of valproic acid and all-trans retinoic acid in patients with poor-risk acute myeloid leukemia
G Bug et al.
CANCER (2005)
Results of a phase 2 study of valproic acid alone or in combination with all-trans retinoic acid in 75 patients with myelodysplastic syndrome and relapsed or refractory acute myeloid leukemia
A Kuendgen et al.
ANNALS OF HEMATOLOGY (2005)
Induction of osteogenic differentiation of human mesenchymal stem cells by histone deacetylase inhibitors
HH Cho et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2005)
Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors
C Bradbury et al.
LEUKEMIA (2005)
Regulation of the expression of the oncogene EVI1 through the use of alternative mRNA 5′-ends
M Aytekin et al.
GENE (2005)
The histone deacetylase inhibitor valproic acid alters sensitivity towards all trans retinoic acid in acute myeloblastic leukemia cells
MR Trus et al.
LEUKEMIA (2005)
Valproic acid stimulates proliferation and self-renewal of hematopoietic stem cells
G Bug et al.
CANCER RESEARCH (2005)
Phase III study of all-trans retinoic acid in previously untreated patients 61 years or older with acute myeloid leukemia
RF Schlenk et al.
LEUKEMIA (2004)
Impact of azacytidine on the quality of life of patients with myelodysplastic syndrome treated in a randomized phase III trial: A cancer and leukemia group B study
AB Kornblith et al.
JOURNAL OF CLINICAL ONCOLOGY (2002)
Hematologic toxicity of sodium valproate
S Acharya et al.
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY (2000)