Journal
JOURNAL OF PERSONALIZED MEDICINE
Volume 11, Issue 3, Pages -Publisher
MDPI
DOI: 10.3390/jpm11030216
Keywords
omics; personalized medicine; Precision Medicine; high-definition medicine
Funding
- AIRC IG [18599, 23190]
- AIRC5X1000 [9979]
- Italian Ministry of Education [2017L8FWY8]
- My First AIRC Grant Luigi Bonatti e Anna Maria Bonatti Rocca [23681]
- Sanofi Genzyme research
- ICPerMed Recognition 2020
- EU Commission
Ask authors/readers for more resources
The emergence of Precision Medicine has revolutionized translational research globally, emphasizing patient-centric therapeutic choices and digitizing individual health status. Real world data-based translational applications offer a promising alternative to traditional evidence-based medicine approaches.
The advent of Precision Medicine has globally revolutionized the approach of translational research suggesting a patient-centric vision with therapeutic choices driven by the identification of specific predictive biomarkers of response to avoid ineffective therapies and reduce adverse effects. The spread of multi-omics analysis and the use of sensors, together with the ability to acquire clinical, behavioral, and environmental information on a large scale, will allow the digitization of the state of health or disease of each person, and the creation of a global health management system capable of generating real-time knowledge and new opportunities for prevention and therapy in the individual person (high-definition medicine). Real world data-based translational applications represent a promising alternative to the traditional evidence-based medicine (EBM) approaches that are based on the use of randomized clinical trials to test the selected hypothesis. Multi-modality data integration is necessary for example in precision oncology where an Avatar interface allows several simulations in order to define the best therapeutic scheme for each cancer patient.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available