Journal
BIOMEDICINES
Volume 9, Issue 5, Pages -Publisher
MDPI
DOI: 10.3390/biomedicines9050483
Keywords
optoacoustics; photoacoustics; imaging inflammation; MSOT; RSOM; PAI; acute inflammation; chronic inflammation; molecular imaging
Categories
Funding
- ELAN Fonds at the University Hospital of the Friedrich-Alexander-Universitat (FAU) Erlangen-Nurnberg [P055]
- Interdisciplinary Center for Clinical Research (IZKF) at the University Hospital of the Friedrich-Alexander-Universitat (FAU) ErlangenNurnberg, Clinician Scientist program
- Else Kroner-Fresenius-Stiftung [2018_EKMS.03]
- European Union's Horizon 2020 research and innovation programme [830965]
- Cancer Research UK [C9545/A29580]
- H2020 Societal Challenges Programme [830965] Funding Source: H2020 Societal Challenges Programme
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Optoacoustic or photoacoustic imaging technology allows non-invasive visualization of laser-illuminated tissue with high resolution and penetration depth, making it a versatile tool for biomedical research. When it comes to imaging inflammation, this technology offers advantages over current clinical methods in diagnosing and monitoring physiological and pathophysiological processes.
Optoacoustic or photoacoustic imaging (OAI/PAI) is a technology which enables non-invasive visualization of laser-illuminated tissue by the detection of acoustic signals. The combination of light in and sound out offers unprecedented scalability with a high penetration depth and resolution. The wide range of biomedical applications makes this technology a versatile tool for preclinical and clinical research. Particularly when imaging inflammation, the technology offers advantages over current clinical methods to diagnose, stage, and monitor physiological and pathophysiological processes. This review discusses the clinical perspective of using OAI in the context of imaging inflammation as well as in current and emerging translational applications.
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