Electrochemical biosensors for rapid pathogen detection

Rapid pathogen detection is an emerging issue in clinical, environmental, and food industry sectors. Biosensors can represent a solution to culture-based and molecular methods as they respond to sensitivity, specificity, and rapidity needs. Screen-printed electrodes have been used in association with nanoparticles to increase the signal and improve sensitivity reaching low numbers of the targets. Antibodies, DNA probes, and aptamers are mainly used to functionalize the working electrodes to ensure high specific pathogen detection by the use of voltammetry, impedance spectroscopy, amperometry, and conductivity. Electrochemical biosensors can be miniaturized to construct portable devices useful for in situ assays.

Automated summary

Electrochemical biosensors offer a rapid and accurate means of detecting pathogens, with applications in clinical, environmental, and food industry sectors. Utilizing screen-printed electrodes in conjunction with nanoparticles can enhance signal and sensitivity, while functionalizing the working electrodes ensures highly specific pathogen detection.