4.7 Article

Microsecond-timescale MD simulation of EGFR minor mutation predicts the structural flexibility of EGFR kinase core that reflects EGFR inhibitor sensitivity

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations

Shinnosuke Ikemura et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Biotechnology & Applied Microbiology

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

Daehwan Kim et al.

NATURE BIOTECHNOLOGY (2019)

Article Multidisciplinary Sciences

AXL confers intrinsic resistance to osimertinib and advances the emergence of tolerant cells

Hirokazu Taniguchi et al.

NATURE COMMUNICATIONS (2019)

Article Multidisciplinary Sciences

A secondary RET mutation in the activation loop conferring resistance to vandetanib

Takashi Nakaoku et al.

NATURE COMMUNICATIONS (2018)

Article Respiratory System

EGFR L747P mutation in one lung adenocarcinoma patient responded to afatinib treatment: a case report

Tong Zhou et al.

JOURNAL OF THORACIC DISEASE (2018)

Article Chemistry, Medicinal

The Effect of Conformational Flexibility on Binding Free Energy Estimation between Kinases and Their Inhibitors

Mitsugu Araki et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2016)

Article Respiratory System

Exon 19 L747P mutation presented as a primary resistance to EGFR-TKI: a case report

Yu-Ting Wang et al.

JOURNAL OF THORACIC DISEASE (2016)

Article Biotechnology & Applied Microbiology

The Ensembl Variant Effect Predictor

William McLaren et al.

GENOME BIOLOGY (2016)

Article Biochemical Research Methods

Trimmomatic: a flexible trimmer for Illumina sequence data

Anthony M. Bolger et al.

BIOINFORMATICS (2014)

Article Biotechnology & Applied Microbiology

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

Kristian Cibulskis et al.

NATURE BIOTECHNOLOGY (2013)

Letter Oncology

A Novel EGFR Mutation in Exon 19 Showed Stable Disease After TKI Treatment

Anthonie J. van der Wekken et al.

JOURNAL OF THORACIC ONCOLOGY (2012)

Article Genetics & Heredity

A framework for variation discovery and genotyping using next-generation DNA sequencing data

Mark A. DePristo et al.

NATURE GENETICS (2011)

Article Medicine, General & Internal

Treatment of Non-Small-Cell Lung Cancer with Erlotinib or Gefitinib

Vince D. Cataldo et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Biochemistry & Molecular Biology

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

Aaron McKenna et al.

GENOME RESEARCH (2010)

Article Biochemical Research Methods

The Sequence Alignment/Map format and SAMtools

Heng Li et al.

BIOINFORMATICS (2009)

Article Physics, Fluids & Plasmas

Massively parallel computation of absolute binding free energy with well-equilibrated states

Hideaki Fujitani et al.

PHYSICAL REVIEW E (2009)

Review Oncology

EGFR Signaling and Drug Discovery

Georg Lurje et al.

ONCOLOGY (2009)

Article Medicine, General & Internal

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

S Kobayashi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)