Journal
EUROPEAN RADIOLOGY
Volume 27, Issue 7, Pages 2928-2933Publisher
SPRINGER
DOI: 10.1007/s00330-016-4651-5
Keywords
Breast; Biopsy; Ultrasound; Core; Needle
Funding
- NCI NIH HHS [P30 CA016672] Funding Source: Medline
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To compare the diagnostic accuracy of ultrasound (US)-guided core needle biopsy (CNB) of breast masses performed with 14-gauge, 16-gauge and 18-gauge needles. We retrospectively reviewed the charts of 1,112 patients who underwent US-guided breast CNB with 14-gauge, 16-gauge and 18-gauge needles. Cases with surgical excision or a minimum of 2 years of imaging follow-up were included. Rates of sample inadequacy, discordance with surgical or imaging findings and upgrade of DCIS to invasive cancer or high-risk lesion to in situ or invasive cancer were computed for each needle size. The study included 703 CNBs: 203 performed with 14-gauge, 235 with 16-gauge and 265 with 18-gauge needles. There were no significant differences between 14-gauge, 16-gauge and 18-gauge needles in rates of specimen inadequacy (0 %, 0.4 % and 1.9 %, respectively) (p = 0.084); surgical discordance (2.6 %, 2.9 % and 3.8 %) (p = 0.76); imaging discordance (0 %, 0 % and 2 %) (p = 1.0); DCIS upgrade (43 %, 43 % and 36 %) (p = 1.00) or high-risk lesion upgrade (38 %, 25 % and 55 %) (p = 0.49). There was no statistically significant difference in diagnostic accuracy of US-guided CNB of breast masses performed with 14-gauge, 16-gauge and 18-gauge needles. aEuro cent Percutaneous image-guided breast core needle biopsy (CNB) is the standard of care. aEuro cent Breast CNB with 14-gauge, 16-gauge and 18-gauge needles has similar diagnostic accuracy. aEuro cent Smaller gauge needles can be confidently used for ultrasound-guided breast CNB.
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