4.7 Article

An Approach to Investigate Content-Related Quality of Nutraceuticals Used by Slovenian Consumers: A Case Study with Folate and Vitamin D Supplements

Journal

FOODS
Volume 10, Issue 4, Pages -

Publisher

MDPI
DOI: 10.3390/foods10040845

Keywords

food supplements; dietary supplements; public health; safety; quality; vitamin D; cholecalciferol; folate; folic acid

Funding

  1. Nutrition Institute research fund (2020)
  2. Slovenian Research Agency [P3-0395, L7-1849]

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The study investigated the vitamin contents of selected food supplements to see if they aligned with labeling, finding some samples outside the 80-150% tolerance interval, particularly 5-MTHF. This highlights the need for better quality control, including during manufacturing and product shelf lifetimes, as well as external controls by authorities.
A predisposition for the efficiency of nutraceuticals is that the product contains a sufficient quantity of a vitamin. Several studies have highlighted different quality issues. Our objective was to investigate whether the contents of the vitamins in selected types of food supplements were in accordance with labeling. We focused on two types of food supplements where content-related quality issues could result in public health risks: food supplements for supplementation with (a) folic acid (as 5-methyltetrahydrofolate (5-MTHF)) in pregnancy and (b) with vitamin D in the general population. The study was done on supplements from the global supply that are typically used by Slovenian consumers. We sampled one production batch of 30 different food supplements-six and 24 samples with 5-MTHF and cholecalciferol, respectively. We found samples with vitamin contents outside the 80-150% tolerance interval in both sets. Particularly, 5-MTHF was found to be more problematic, probably due to its lower stability. This study shows the need for better quality control. Quality control is needed during both the manufacturing process and product shelf lifetimes. Content quality should be also subject to external controls by authorities. Voluntarily quality control schemes would also enable consumers to identify products of sufficient quality.

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