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Thrombin regulates the expression of proangiogenic cytokines via proteolytic activation of protease-activated receptor-1
A Naldini et al.
GENERAL PHARMACOLOGY-THE VASCULAR SYSTEM (2000)
Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-κB
J Ryu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Potentiation of NMDA receptor function by the serine protease thrombin
MB Gingrich et al.
JOURNAL OF NEUROSCIENCE (2000)
The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations
F Striggow et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)