Journal
MOLECULAR CATALYSIS
Volume 505, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.mcat.2021.111462
Keywords
Alkylation of indole; Cu catalysis; Hydrogen borrowing; Indole functionalization; Sustainable process
Categories
Funding
- Vietnam National Foundation for Science and Technology Development (NAFOSTED) [104.012018.30]
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A highly efficient copper(II) catalyst system has been developed for alkylation of indoles with alcohols via hydrogen borrowing method, yielding C3-alkylated indoles in good to excellent yields. The combination of Cu(OAc)(2) with dppm ligand has been found to be the most suitable catalyst system for this alkylation reaction.
A highly efficient copper(II) catalyst system for alkylation of indoles with alcohols via hydrogen borrowing method has been developed to afford C3-alkylated indoles in good to excellent yields. Cu(OAc)(2) in the combination with dppm ligand has been found to be the most suitable catalyst system for this alkylation reaction.
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