Journal
OPEN FORUM INFECTIOUS DISEASES
Volume 8, Issue 5, Pages -Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/ofid/ofab180
Keywords
breastfeeding; COVID-19; pregnancy; SARS-CoV-2; vaccine
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Despite the lack of data on vaccine safety in pregnant and breastfeeding individuals, the known risks of COVID-19 during pregnancy likely outweigh the potential risks of SARS-CoV-2 vaccines, which have demonstrated reassuring safety and efficacy profiles in nonpregnant populations.
As the first severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines passed UK and US regulatory milestones in late 2020 and early 2021, multiple professional societies offered recommendations to assist pregnant and breastfeeding people as they choose whether to undergo vaccination. Despite such guidance, the lack of data describing vaccine safety, immunogenicity, and efficacy in pregnant and breastfeeding people has made this decision challenging for many. However, even considering the paucity of data, the known risks of coronavirus disease 2019 during pregnancy likely outweigh the not yet fully elucidated risks of SARS-CoV-2 vaccines, which have reassuring safety and efficacy profiles among nonpregnant people.
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