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Chronic lymphocytic leukemia B cells expressing AID display dissociation between class switch recombination and somatic hypermutation
P Oppezzo et al.
BLOOD (2003)
Constitutive expression of AID leads to tumorigenesis
I Okazaki et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells
KF Yu et al.
NATURE IMMUNOLOGY (2003)
Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand
AR Ramiro et al.
NATURE IMMUNOLOGY (2003)
Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas
J Greeve et al.
BLOOD (2003)
Transcription-targeted DNA deamination by the AID antibody diversification enzyme
J Chaudhuri et al.
NATURE (2003)
Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase
R Bransteitter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Class-switch recombination: after the dawn of AID
AL Kenter
CURRENT OPINION IN IMMUNOLOGY (2003)
Human activation-induced cytidine deaminase is induced by IL-4 and negatively regulated by CD45: Implication of CD45 as a Janus kinase phosphatase in antibody diversification
C Zhou et al.
JOURNAL OF IMMUNOLOGY (2003)
Do CLL B cells correspond to naive or memory B-lymphocytes? Evidence for an active Ig switch unrelated to phenotype expression and Ig mutational pattern in B-CLL cells
P Oppezzo et al.
LEUKEMIA (2002)
Ongoing in vivo immunoglobulin class switch DNA recombination in chronic lymphocytic leukemia B cells
A Cerutti et al.
JOURNAL OF IMMUNOLOGY (2002)
Measurement in vivo of proliferation rates of slow turnover cells by 2H2O labeling of the deoxyribose moiety of DNA
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice
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CURRENT BIOLOGY (2002)
Chronic lymphocytic leukemia B cells can undergo somatic hypermutation and intraclonal immunoglobulin VHDJH gene diversification
C Gurrieri et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line
A Faili et al.
NATURE IMMUNOLOGY (2002)
AID-GFP chimeric protein increases hypermutation of Ig genes with no evidence of nuclear localization
C Rada et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Distinct role of CD80 and CD86 in the regulation of the activation of B cell and B cell lymphoma
S Suvas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion
H Arakawa et al.
SCIENCE (2002)
Mechanisms of chromosomal translocations in B cell lymphomas
R Küppers et al.
ONCOGENE (2001)
The intrinsic hypermutability of antibody heavy and light chain genes decays exponentially
C Rada et al.
EMBO JOURNAL (2001)
Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas
L Pasqualucci et al.
NATURE (2001)
Genomic aberrations and survival in chronic lymphocytic leukemia.
H Döhner et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)
Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction
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JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Isolation, tissue distribution, and chromosomal localization of the human activation-induced cytidine deaminase (AID) gene
T Muto et al.
GENOMICS (2000)
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