Journal
FRONTIERS IN ONCOLOGY
Volume 11, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fonc.2021.633827
Keywords
nano-radiosensitizer; radiotherapy; radiation sensitization; nanoparticles; glioma
Categories
Funding
- National Natural Science Foundation of China [81772665]
- Social Development Project of Jiangsu Department of Science and Technology [BE2020647, BE2020642]
- Jiangsu provincial Commission of Health and Family Planning [Q201608]
- Six Talents Peak Foundation of Jiangsu Province [2018-WSW-071]
- Youth Science and Technology Innovation Team of Xuzhou Medical University [TD202002]
- Social Development Project of Xuzhou Department of Science and Technology [KC20079]
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Glioma, the most common intracranial malignant tumor, remains a clinical challenge with limited therapeutic options. Nano-radiosensitizers show promise in improving the sensitivity of glioma to radiotherapy, offering a potential new treatment approach.
Glioma is the most common intracranial malignant tumor, and its specific pathogenesis has been unclear, which has always been an unresolved clinical problem due to the limited therapeutic window of glioma. As we all know, surgical resection, chemotherapy, and radiotherapy are the main treatment methods for glioma. With the development of clinical trials and traditional treatment techniques, radiotherapy for glioma has increasingly exposed defects in the treatment effect. In order to improve the bottleneck of radiotherapy for glioma, people have done a lot of work; among this, nano-radiosensitizers have offered a novel and potential treatment method. Compared with conventional radiotherapy, nanotechnology can overcome the blood-brain barrier and improve the sensitivity of glioma to radiotherapy. This paper focuses on the research progress of nano-radiosensitizers in radiotherapy for glioma.
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