4.6 Review

Role of SHH in Patterning Human Pluripotent Cells towards Ventral Forebrain Fates

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment

Cleber A. Trujillo et al.

Summary: The evolutionarily conserved splicing regulator NOVA1 plays a crucial role in neural development and function, with a protein-coding difference between modern humans and Neanderthals. Reintroducing the archaic allele of NOVA1 into human induced pluripotent cells resulted in slower neural development and increased surface complexity, reflecting potential functional consequences for human evolution.

SCIENCE (2021)

Article Cell & Tissue Engineering

Cell-to-Cell Adhesion and Neurogenesis in Human Cortical Development: A Study Comparing 2D Monolayers with 3D Organoid Cultures

Soraya Scuderi et al.

Summary: In this study, transcriptome and cellular phenotypes of telencephalic organoids (ORGs) and monolayers (MONs) derived from induced pluripotent stem cells (iPSCs) were compared. The results revealed increased proliferation and altered cellular characteristics in MONs, suggesting potential differences in signaling pathways and developmental processes when compared to ORGs.

STEM CELL REPORTS (2021)

Review Cell Biology

Human organoids: model systems for human biology and medicine

Jihoon Kim et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)

Review Neurosciences

Challenges in Modeling Human Neural Circuit Formation via Brain Organoid Technology

Takeshi K. Matsui et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2020)

Article Multidisciplinary Sciences

The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon

Hikaru Eto et al.

NATURE COMMUNICATIONS (2020)

Article Biochemistry & Molecular Biology

Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution

Alex A. Pollen et al.

Article Biotechnology & Applied Microbiology

Specification of positional identity in forebrain organoids

Gustav Y. Cederquist et al.

NATURE BIOTECHNOLOGY (2019)

Review Biotechnology & Applied Microbiology

Engineering Organoid Vascularization

Sergei Grebenyuk et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2019)

Article Biochemistry & Molecular Biology

MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling

N. Mellios et al.

MOLECULAR PSYCHIATRY (2018)

Article Biotechnology & Applied Microbiology

An in vivo model of functional and vascularized human brain organoids

Abed AlFatah Mansour et al.

NATURE BIOTECHNOLOGY (2018)

Article Multidisciplinary Sciences

Transcriptome and epigenome landscape of human cortical development modeled in organoids

Anahita Amiri et al.

SCIENCE (2018)

Review Multidisciplinary Sciences

The rise of three-dimensional human brain cultures

Sergiu P. Pasca

NATURE (2018)

Article Multidisciplinary Sciences

Assembly of functionally integrated human forebrain spheroids

Fikri Birey et al.

NATURE (2017)

Article Multidisciplinary Sciences

Cell diversity and network dynamics in photosensitive human brain organoids

Giorgia Quadrato et al.

NATURE (2017)

Article Biochemical Research Methods

Fused cerebral organoids model interactions between brain regions

Joshua A. Bagley et al.

NATURE METHODS (2017)

Review Clinical Neurology

Human induced pluripotent stem cells for modelling neurodevelopmental disorders

Karthikeyan Ardhanareeswaran et al.

NATURE REVIEWS NEUROLOGY (2017)

Review Neurosciences

The use of brain organoids to investigate neural development and disease

Elizabeth Di Lullo et al.

NATURE REVIEWS NEUROSCIENCE (2017)

Article Neurosciences

Characterization of Induced Pluripotent Stem Cell-derived Human Serotonergic Neurons

Lining Cao et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2017)

Article Biotechnology & Applied Microbiology

Generation of serotonin neurons from human pluripotent stem cells

Jianfeng Lu et al.

NATURE BIOTECHNOLOGY (2016)

Article Biochemistry & Molecular Biology

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

Xuyu Qian et al.

Article Biochemistry & Molecular Biology

Role of Sonic Hedgehog Signaling in Oligodendrocyte Differentiation

Li-Chun Wang et al.

NEUROCHEMICAL RESEARCH (2016)

Article Biochemistry & Molecular Biology

Molecular Identity of Human Outer Radial Glia during Cortical Development

Alex A. Pollen et al.

Article Multidisciplinary Sciences

Human cerebral organoids recapitulate gene expression programs of fetal neocortex development

J. Gray Camp et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

Generation and expansion of highly pure motor neuron progenitors from human pluripotent stem cells

Zhong-Wei Du et al.

NATURE COMMUNICATIONS (2015)

Article Multidisciplinary Sciences

Cerebral organoids model human brain development and microcephaly

Madeline A. Lancaster et al.

NATURE (2013)

Review Pharmacology & Pharmacy

Serotonin receptors involved in antidepressant effects

Francesc Artigas

PHARMACOLOGY & THERAPEUTICS (2013)

Article Mathematical & Computational Biology

The emergence of two anti-phase oscillatory neural populations in a computational model of the Parkinsonian globus pallidus

Robert Merrison-Hort et al.

FRONTIERS IN COMPUTATIONAL NEUROSCIENCE (2013)

Article Biochemical Research Methods

Generation of human induced pluripotent stem cells from urine samples

Ting Zhou et al.

NATURE PROTOCOLS (2012)

Article Multidisciplinary Sciences

Modeling human cortical development in vitro using induced pluripotent stem cells

Jessica Mariani et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Biochemistry & Molecular Biology

Development and Evolution of the Human Neocortex

Jan H. Lui et al.

Article Urology & Nephrology

Generation of Induced Pluripotent Stem Cells from Urine

Ting Zhou et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2011)

Article Developmental Biology

The Relationship between Sonic Hedgehog Signaling, Cilia, and Neural Tube Defects

Jennifer N. Murdoch et al.

BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY (2010)

Article Cell & Tissue Engineering

Reprogramming of T Cells from Human Peripheral Blood

Yuin-Han Loh et al.

CELL STEM CELL (2010)

Article Cell & Tissue Engineering

Reprogramming of Human Peripheral Blood Cells to Induced Pluripotent Stem Cells

Judith Staerk et al.

CELL STEM CELL (2010)

Article Multidisciplinary Sciences

α-Synuclein gene duplication impairs reward learning

Szabolcs Keri et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biotechnology & Applied Microbiology

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

Stuart M. Chambers et al.

NATURE BIOTECHNOLOGY (2009)

Article Biochemistry & Molecular Biology

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

Kazutoshi Takahashi et al.

Article Genetics & Heredity

Dopaminergic polymorphisms in Tourette syndrome:: Association with the DAT gene (SLC6A3)

Dustin Y. Yoon et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2007)

Review Neurosciences

The floor plate: Multiple cells, multiple signals

M Placzek et al.

NATURE REVIEWS NEUROSCIENCE (2005)

Article Developmental Biology

Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon

M Backman et al.

DEVELOPMENTAL BIOLOGY (2005)