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Isolated Toll-like Receptor Transmembrane Domains Are Capable of Oligomerization
James I. Godfroy et al.
PLOS ONE (2012)
A study of split-dose cisplatin-based neo-adjuvant chemotherapy in muscle-invasive bladder cancer
S. A. Hussain et al.
ONCOLOGY LETTERS (2012)
The role of TLR2 in infect on and immunity
Laura Oliveira-Nascimento et al.
FRONTIERS IN IMMUNOLOGY (2012)
Role of leukocytes in the pathogenesis of acute kidney injury
Gilbert R. Kinsey et al.
CRITICAL CARE (2012)
Membrane Transporters as Mediators of Cisplatin Effects and Side Effects
Giuliano Ciarimboli
SCIENTIFICA (2012)
Toll-Like Receptor 4 Inhibitor TAK-242 Attenuates Acute Kidney Injury in Endotoxemic Sheep
Johan Fenhammar et al.
ANESTHESIOLOGY (2011)
Imatinib treatment duration is related to decreased estimated glomerular filtration rate in chronic myeloid leukemia patients
M. S. Marcolino et al.
ANNALS OF ONCOLOGY (2011)
The pro- and anti-inflammatory properties of the cytokine interleukin-6
Juergen Scheller et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
Poly(ADP-ribose) polymerase-1 is a key mediator of cisplatin-induced kidney inflammation and injury
Partha Mukhopadhyay et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Dynamics of the Degradation of Ubiquitinated Proteins by Proteasomes and Autophagy ASSOCIATION WITH SEQUESTOSOME 1/p62
Natura Myeku et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Cellular pathophysiology of ischemic acute kidney injury
Joseph V. Bonventre et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
IL-33 Exacerbates Acute Kidney Injury
Ali Akcay et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2011)
Interleukin-6 plays a protective role in development of cisplatin-induced acute renal failure through upregulation of anti-oxidative stress factors
Satoru Mitazaki et al.
LIFE SCIENCES (2011)
Renal TLR4 mRNA Expression Correlates with Inflammatory Marker MCP-1 and Profibrotic Molecule TGF-beta(1) in Patients with Chronic Kidney Disease
Julia Lepenies et al.
NEPHRON CLINICAL PRACTICE (2011)
The Tumor Lysis Syndrome
Scott C. Howard et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Necrotic Concentrations of Cisplatin Activate the Apoptotic Machinery but Inhibit Effector Caspases and Interfere with the Execution of Apoptosis
Sandra M. Sancho-Martinez et al.
TOXICOLOGICAL SCIENCES (2011)
Organic Cation Transporter 2 Mediates Cisplatin-Induced Oto- and Nephrotoxicity and Is a Target for Protective Interventions
Giuliano Ciarimboli et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Disruption of multidrug and toxin extrusion MATE1 potentiates cisplatin-induced nephrotoxicity
Takanori Nakamura et al.
BIOCHEMICAL PHARMACOLOGY (2010)
Vascular Endothelial Function and Hypertension: Insights and Directions
Kodlipet Dharmashankar et al.
CURRENT HYPERTENSION REPORTS (2010)
Endoplasmic reticulum stress as a progression factor for kidney injury
Reiko Inagi
CURRENT OPINION IN PHARMACOLOGY (2010)
The Toll-like receptor 2 (TLR2) ligand FSL-1 is internalized via the clathrin-dependent endocytic pathway triggered by CD14 and CD36 but not by TLR2
Haque M. Shamsul et al.
IMMUNOLOGY (2010)
Regulation of the autophagy protein LC3 by phosphorylation
Salvatore J. Cherra et al.
JOURNAL OF CELL BIOLOGY (2010)
Human TLRs 10 and 1 Share Common Mechanisms of Innate Immune Sensing but Not Signaling
Yue Guan et al.
JOURNAL OF IMMUNOLOGY (2010)
Endogenous IL-10 Attenuates Cisplatin Nephrotoxicity: Role of Dendritic Cells
Raghu Kempegowda Tadagavadi et al.
JOURNAL OF IMMUNOLOGY (2010)
Molecular mechanisms of necroptosis: an ordered cellular explosion
Peter Vandenabeele et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Expression of Toll-like receptor 9 in renal podocytes in childhood-onset active and inactive lupus nephritis
Hiroyuki Machida et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2010)
DAMPening Inflammation by Modulating TLR Signalling
A. M. Piccinini et al.
MEDIATORS OF INFLAMMATION (2010)
Mechanisms of Cisplatin Nephrotoxicity
Ronald P. Miller et al.
TOXINS (2010)
Urine interleukin-6 is an early biomarker of acute kidney injury in children undergoing cardiac surgery
Paula Dennen et al.
CRITICAL CARE (2010)
Role of the Unfolded Protein Response Regulator GRP78/BiP in Development, Cancer, and Neurological Disorders
Miao Wang et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
Protective effect of concomitant administration of imatinib on cisplatin-induced nephrotoxicity focusing on renal organic cation transporter OCT2
Yuko Tanihara et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Role of glutathione S-transferase Pi in cisplatin-induced nephrotoxicity
Danyelle M. Townsend et al.
BIOMEDICINE & PHARMACOTHERAPY (2009)
Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model
K. Takashima et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Chemokine/chemokine receptor-mediated inflammation regulates pathologic changes from acute kidney injury to chronic kidney disease
Kengo Furuichi et al.
CLINICAL AND EXPERIMENTAL NEPHROLOGY (2009)
Role of oxidative and nitrosative stress in cisplatin-induced nephrotoxicity
Yolanda I. Chirino et al.
EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY (2009)
Ligation of TLR9 induced on human IL-10-secreting Tregs by 1α,25-dihydroxyvitamin D3 abrogates regulatory function
Zoe Urry et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Multiple signaling pathways contribute to synergistic TLR ligand-dependent cytokine gene expression in human monocyte-derived macrophages and dendritic cells
Sanna M. Makela et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2009)
Glomerular expression of toll-like receptor-9 in lupus nephritis but not in normal kidneys: implications for the amplification of the inflammatory response
E. D. Papadimitraki et al.
LUPUS (2009)
RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
Duan-Wu Zhang et al.
SCIENCE (2009)
Cisplatin Ototoxicity and Protection: Clinical and Experimental Studies
Leonard P. Rybak et al.
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Interleukin-6 deficiency accelerates cisplatin-induced acute renal failure but not systemic injury
S. Mitazaki et al.
TOXICOLOGY (2009)
The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity
Navjotsingh Pabla et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2009)
Tumor necrosis factor and cancer, buddies or foes?
Xia Wang et al.
ACTA PHARMACOLOGICA SINICA (2008)
Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells
Ganna V. Kalayda et al.
BMC CANCER (2008)
Nebivolol:: A highly selective β1-adrenergic receptor blocker that causes vasodilation by increasing nitric oxide
Sandeep Gupta et al.
CARDIOVASCULAR THERAPEUTICS (2008)
Novel biologic mechanisms of levosimendan and its effect on the failing heart
John T. Parissis et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2008)
TLR4 signaling mediates inflammation and tissue injury in nephrotoxicity
Binzhi Zhang et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2008)
Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies
N. Pabla et al.
KIDNEY INTERNATIONAL (2008)
Acute kidney injury
Norbert Lameire et al.
LANCET (2008)
Expression of nucleic acid binding Toll-like receptors in control, lupus and transplanted kidneys - a preliminary pilot study
H. Ciferska et al.
LUPUS (2008)
Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling
Katja Farhat et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2008)
Increased macrophage infiltration and fractalkine expression in cisplatin-induced acute renal failure in mice
Lawrence H. Lu et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
The anticancer drug cisplatin induces an intrinsic apoptotic pathway inside the inner ear
J. R. Garcia-Berrocal et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
Functional outcome of B cell activation by chromatin immune complex engagement of the B cell receptor and TLR9
Liliana Busconi et al.
JOURNAL OF IMMUNOLOGY (2007)
Cisplatin, gentamicin, and p-aminophenol induce markers of endoplasmic reticulum stress in the rat kidneys
Mathieu Peyrou et al.
TOXICOLOGICAL SCIENCES (2007)
Cisplatin-induced nephrotoxicity is mediated by tumor necrosis factor-α produced by renal parenchymal cells
B. Zhang et al.
KIDNEY INTERNATIONAL (2007)
Endotoxin and cisplatin synergistically induce renal dysfunction and cytokine production in mice
Ganesan Ramesh et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2007)
Cisplatin-induced acute renal failure is associated with an increase in the cytokines interleukin (IL)-1β, IL-18, IL-6, and neutrophil infiltration in the kidney
Sarah Faubel et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate toll-like receptors
Norio Matsushima et al.
BMC GENOMICS (2007)
TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways
Alana A. Shigeoka et al.
JOURNAL OF IMMUNOLOGY (2007)
Inhibition of CXCL16 attenuates inflammatory and progressive phases of anti-glomerular basement membrane antibody-associated glomerulonephritis
Gabriela E. Garcia et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
Mechanisms of cisplatin-induced ototoxicity and prevention
Leonard P. Rybak et al.
HEARING RESEARCH (2007)
The role of toll-like receptor 4 in cisplatin-induced renal injury
M. A. Cenedeze et al.
TRANSPLANTATION PROCEEDINGS (2007)
CXCL16 is a marker of inflammation, atherosclerosis, and acute coronary syndromes in humans
Michael Lehrke et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2007)
MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists
Aranya Bagchi et al.
JOURNAL OF IMMUNOLOGY (2007)
Angiotensin-(1-7) through receptor Mas mediates endothelial nitric oxide synthase activation via Akt-dependent pathways
Walkyria Oliveira Sampaio et al.
HYPERTENSION (2007)
The roles of copper transporters in cisplatin resistance
Macus Tien Kuo et al.
CANCER AND METASTASIS REVIEWS (2007)
Influence of nebivolol and metoprolol on inflammatory mediators in human coronary endothelial or smooth muscle cells. Effects on neointima formation after balloon denudation in carotid arteries of rats treated with nebivolol
Sabine C. Wolf et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2007)
Cisplatin and oxaliplatin, but not carboplatin and nedaplatin, are substrates for human organic cation transporters (SLC22A1-3 and multidrug and toxin extrusion family)
Atsushi Yonezawa et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Dependence of cisplatin-induced cell death in vitro and in vivo on cyclin-dependent kinase 2
Peter M. Price et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
Regulation of PUMA-α by p53 in cisplatin-induced renal cell apoptosis
M. Jiang et al.
ONCOGENE (2006)
Turning point in apoptosis/necrosis induced by hydrogen peroxide
Yoshiro Saito et al.
FREE RADICAL RESEARCH (2006)
A pathophysiologic role for T lymphocytes in murine acute cisplatin nephrotoxicity
Manchang Liu et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
Pathogen recognition and innate immunity
S Akira et al.
CELL (2006)
Novel role of Toll-like receptor 3 in hepatitis C-associated glomerulonephritis
M Wörnle et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Toll-like receptor 9 signaling protects against murine lupus
XB Wu et al.
ARTHRITIS AND RHEUMATISM (2006)
Cisplatin nephrotoxicity is critically mediated via the human organic cation transporter 2
G Ciarimboli et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Discovery of novel and potent small-molecule inhibitors of NO and cytokine production as antisepsis agents: Synthesis and biological activity of alkyl 6-(N-substituted sulfamoyl)cyclohex-1-ene-1-carboxylate
M Yamada et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Oxalate toxicity in renal cells
JA Jonassen et al.
UROLOGICAL RESEARCH (2005)
Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney
JC Leemans et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Expression of Toll-like receptor 9 and response to bacterial CpG oligodeoxynucleotides in human intestinal epithelium
G Pedersen et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2005)
Severe neurotoxicity, ototoxicity and nephrotoxicity following high-dose cisplatin and amifostine
J Sastry et al.
PEDIATRIC HEMATOLOGY AND ONCOLOGY (2005)
p38 MAP kinase inhibition ameliorates cisplatin nephrotoxicity in mice
G Ramesh et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2005)
Endoplasmic reticulum stress-associated caspase 12 mediates cisplatin-induced LLC-PK1 cell apoptosis
H Liu et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2005)
Relevance of Toll-like receptor-4 polymorphisms in renal transplantation
D Ducloux et al.
KIDNEY INTERNATIONAL (2005)
Toll-like receptor 4 contributes to efficient control of infection with the protozoan parasite Leishmania major
P Kropf et al.
INFECTION AND IMMUNITY (2004)
A toll-like receptor that prevents infection by uropathogenic bacteria
DK Zhang et al.
SCIENCE (2004)
Death by design: apoptosis, necrosis and autophagy
AL Edinger et al.
CURRENT OPINION IN CELL BIOLOGY (2004)
Toll-like receptor 4 expression and cytokine responses in the human urinary tract mucosa
P Samuelsson et al.
INFECTION AND IMMUNITY (2004)
Activation of TBK1 and IKKε kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity
BR tenOever et al.
JOURNAL OF VIROLOGY (2004)
Leucine-rich repeats and pathogen recognition in Toll-like receptors
JK Bell et al.
TRENDS IN IMMUNOLOGY (2003)
Tumour necrosis factor α:: a potential target for the therapy of solid tumours
PW Szlosarek et al.
LANCET ONCOLOGY (2003)
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
M Yamamoto et al.
SCIENCE (2003)
Cytochrome P450 2E1 null mice provide novel protection against cisplatin-induced nephrotoxicity and apoptosis
H Liu et al.
KIDNEY INTERNATIONAL (2003)
Cisplatin induces endoplasmic reticulum stress and nucleus-independent apoptotic signaling
A Mandic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Divergent roles of angiotensin II AT1 and AT2 receptors in modulating coronary microvascular function
CH Zhang et al.
CIRCULATION RESEARCH (2003)
Direct involvement of the receptor-mediated apoptotic pathways in cisplatin-induced renal tubular cell death
K Tsuruya et al.
KIDNEY INTERNATIONAL (2003)
Maturation of dendritic cell 2 phenotype by a helminth glycan uses a toll-like receptor 4-dependent mechanism
PG Thomas et al.
JOURNAL OF IMMUNOLOGY (2003)
Metabolism of cisplatin to a nephrotoxin in proximal tubule cells
DM Townsend et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2003)
The copper transporter CTR1 regulates cisplatin uptake in Saccharomyces cerevisiae
XJ Lin et al.
MOLECULAR PHARMACOLOGY (2002)
Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals
S Ishida et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
TNF-α mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity
G Ramesh et al.
JOURNAL OF CLINICAL INVESTIGATION (2002)
Angiotensin type 2 receptor antagonism confers renal protection in a rat model of progressive renal injury
ZM Cao et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2002)
Nitric oxide modulates superoxide release and peroxynitrite, formation in human blood vessels
TJ Guzik et al.
HYPERTENSION (2002)
Tissue expression of human toll-like receptors and differential regulation of toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
KA Zarember et al.
JOURNAL OF IMMUNOLOGY (2002)
Interleukin-10 inhibits ischemic and cisplatin-induced acute renal injury
JP Deng et al.
KIDNEY INTERNATIONAL (2001)
Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virus
LM Haynes et al.
JOURNAL OF VIROLOGY (2001)
The evolution and genetics of innate immunity
DA Kimbrell et al.
NATURE REVIEWS GENETICS (2001)
Induction of innate immune responses by Escherichia coli and purified lipopolysaccharide correlate with organ- and cell-specific expression of Toll-like receptors within the human urinary tract
F Bäckhed et al.
CELLULAR MICROBIOLOGY (2001)
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
EA Kurt-Jones et al.
NATURE IMMUNOLOGY (2000)
Toll-like receptors in the induction of the innate immune response
A Aderem et al.
NATURE (2000)
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